Results 281 to 290 of about 10,319,593 (322)

Specific anti-antibody in transplantation

Experientia, 1968
Durch ein immunologisches Dreieck-System (Hund-Kaninchen-Hund) wurde ein Anti-Antikorper bei Hunden erzeugt und seine Wirkung in vitro und in vivo demonstriert. Die Anti-Antikorper-Methode bietet neue Moglichkeiten, dem Problem der Transplantat-Abstossung und der Therapie der Krankheiten immunologischen Ursprungs naherzukommen.
N, Radoiu, F A, Zydeck, E T, Konno, P L, Wolf   +3 more
openaire   +2 more sources

Engineering antibody affinity and specificity

International Journal of Cancer, 1988
A combination of ab initio calculations, "knowledge-based prediction", molecular graphics and site-directed mutagenesis has enabled us to probe the molecular details of antibody:antigen recognition and binding and to alter the affinity and specificity of an antibody for its antigen.
D M, Webster, S, Roberts, J C, Cheetham, R, Griest, A R, Rees   +4 more
openaire   +2 more sources

Specificity of Antibodies

Nature, 1968
The Structural Basis of Antibody Specificity By David Pressman and Allan L. Grossberg. (Microbial and Molecular Biology Series.) Pp. xvii + 279. (Benjamin: New York and Amsterdam, 1968.) $16.75.
openaire   +1 more source

Purification and specificity of antibodies to adenosine

Biochimie, 1977
Antibodies to adenosine were elicited in rabbits by immunization with bovine serum albumin-adenosine conjugate. The antibodies were purified and fractionated on two affinity columns (Sepharose-oligo(A) and Sepharose-AMP). Two families of antibodies have been obtained.
J, Lavayre, M, Leng
openaire   +2 more sources

Phospho-specific antibodies by design

Nature Biotechnology, 2013
Antibodies specific to phosphorylated peptides are readily generated through structure-based engineering and in vitro selection.
Oda Stoevesandt, Michael J Taussig
openaire   +2 more sources

On the structure of a specific antibody site

Journal of Theoretical Biology, 1963
Abstract The specific combining region of an antibody molecule has been assumed to be a fixed property of the molecule. However, this assumption is unlikely if the antigen plays an instructive role in antibody formation. A simpler model of the specific site must be considered.
openaire   +2 more sources

Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning

Nature Biomedical Engineering, 2021
Derek M. Mason, Simon Friedensohn, Cédric R. Weber, Christian Jordi, Bastian Wagner, Simon M Meng, R. Ehling, Lucia Bonati, J. Dahinden, P. Gainza, B. Correia, S. Reddy   +11 more
semanticscholar   +1 more source

Anti-DNA Antibodies: Specificity?

Annals of Internal Medicine, 1973
Excerpt To the editor: I read with interest the review on recent advances in rheumatoid diseases (Ann Intern Med77:455-464, 1972).
openaire   +2 more sources

Development of an S-bioallethrin specific antibody

Journal of Agricultural and Food Chemistry, 1978
Residue analysis of the pyrethrins and allethrin as well as newer pyrethroid insecticides not containing halogens such as resmethrin and phenothrin is expensive, tedious, and/or of poor sensitivity. The structure of such pyrethroids suggests that they can be analyzed quickly, inexpensively, and at low levels by radioimmunoassay.
K D, Wing, B D, Hammock, D A, Wustner
openaire   +2 more sources

SPECIFICITY OF TRANSPLANTATION HETEROPHILE ANTIBODIES

Transplantation, 1984
Sera of 154 recipients of renal allografts were studied for transplantation heterophile (T-H) antibodies by means of immunodiffusion, mixed agglutination (MA) and enzyme immunoassay (EIA). T-H antibodies were found by immunodiffusion against bovine red blood cell (BRBC) extracts (15%) and sheep red blood cell (SRBC) extracts (12%): The specificity of ...
T, Tamura, K, Kano, F, Milgrom
openaire   +2 more sources