Results 231 to 240 of about 241,274 (262)

Toward Nano‐Nutritional Medicine: A Remotely Activated Trans‐Vaccenic Acid‐Based Lipid Nanoparticles for Enhancing Immune Checkpoint Blockade Therapy

Advanced Science, EarlyView.
Eutectic mixtures from trans‐vaccenic acid (TVA) and stearic acid, which served as phase‐change material to encapsulate IR780, forming NIR‐responsive nanoparticles. IR780@TVA LNPs induce photothermal therapy and initiate adaptive anti‐tumor immunity.
Kang Liu, Yunlong Li, Hanmeng Liu, Peng Zhang, Mingjing Wang, Quanwei Sun, Wenshuo Yang, Zhengwei Song, Song Tan, Ye Yang, Peng She, Dengke Yin, Wei Shen   +12 more
wiley   +1 more source

<i>Dendrophthoe pentandra</i> (L.) Miq. as a Source of Anticancer Agents: A Review of Phytochemical Constituents and Preclinical Efficacy. [PDF]

Drug Des Devel Ther
Anggraini L, Febriyanti RM, Muhaimin M, Endrini S.   +3 more
europepmc   +1 more source

Tumor‐Specific Delivery of CD28 siRNA via Lyso‐PC C‐16 Modified Lipid Nanoparticles Overcomes Anti‐PD‐1 Resistance by Remodeling Tumor Microenvironment

Advanced Science, EarlyView.
This study develops 16:0 LPC‐modified lipid nanoparticles (LPC‐LNPs) with cancer cell specificity by exploiting altered tumor lipid metabolism. LPC‐LNPs encapsulating Cd28 small interfering RNA (LPC‐LNP‐Cd28) knock down cancer cell CD28 without affecting T cells, inflame the tumor microenvironment, and overcome anti‐PD‐1 resistance.
Yangyang Chai, Keyu Wang, Jiali Fang, Shaorui Jia, Yansong Shi, Wanfeng Gao, Xinpeng Liu, Jiaqiang Li, Zenghui Cui, Yazhi Qian, Xiaosu Chen, Dan Ding, Xuetao Cao   +12 more
wiley   +1 more source

A two-decade overview of oxadiazole derivatives as promising anticancer agents. [PDF]

RSC Adv
Salem M, El-Adl K, El-Morsy A, Abulkhair HS.   +3 more
europepmc   +1 more source

Coumarin Derivatives as Anticancer Agents: Mechanistic Landscape with an Emphasis on Breast Cancer. [PDF]

Molecules
Hacholli VB, R SM, H PB, M L, S P, Kumar A, Szeleszczuk Ł, Gackowski M.   +7 more
europepmc   +1 more source

Mitochondria-targeting symmetric diiminoguanidines: potent and selective anticancer agents against pancreatic tumors. [PDF]

RSC Med Chem
Lacaille S, Schmitzer AR.
europepmc   +1 more source

Design and Pictet-Spengler enabled synthesis of carboxamide-substituted imidazo[1,2-<i>a</i>]quinoxalines as dual EGFR and tubulin targeting anticancer agents. [PDF]

J Enzyme Inhib Med Chem
Chatterjee J, Joshi G, Jha V, Bhujbal SM, Rathour S, Majumdar S, Wahajuddin M, Bharatam PV, Kumar R.   +8 more
europepmc   +1 more source

Multi-omics and pan-cancer analysis revealed common molecular signatures to disclose multitargeted anticancer agents through network pharmacology approach. [PDF]

PLoS One
Sarker H, Farid FB, Kamrun M, Masud E, Ahmed A, Miah M, Roy NS, Kumar N, Ali MA.   +8 more
europepmc   +1 more source

Improving the Dosing Schedules of Targeted Anticancer Agents. [PDF]

Pharmaceuticals (Basel)
Levêque D.
europepmc   +1 more source