Results 151 to 160 of about 3,277,334 (211)
Novel coumarins as potential anticarcinogenic agents
The potential anticarcinogenic properties of several novel coumarin derivatives whose structures are based on polycyclic aromatic hydrocarbons (PAHs) were examined in the multistage model of mouse skin tumorigenesis. The test compounds were evaluated for their affinity to bind competitively with rat cytosolic Ah-receptor in rat hepatic cytosol, their ...
Raghunathan V. Nair +5 more
semanticscholar +4 more sources
Naturally Occurring Phenolics as Antimutagenic and Anticarcinogenic Agents
Epidemiological evidence points to an inverse relationship between the consumption of vegetables and the incidence of cancer at various sites (Hirayama, 1979, 1981; Graham et al., 1978; Mettlin et al., 1981). The search for the protective components in these vegetables has focused on B-carotene and vitamin A (e.g., Bjelke, 1975; Shekelle et al., 1981 ...
H. F. Stich, Miriam P. Rosin
semanticscholar +4 more sources
A large body of evidence indicates that lignans as polyphenolic compounds are beneficial against life-threatening diseases such as cancer. Plant lignans have the potential to induce cancer cell death and interfere with carcinogenesis, tumor growth, and metastasis.
Sayeh Mottaghi, Hassan Abbaszadeh
semanticscholar +4 more sources
Sesquiterpenes from Clove (Eugenia caryophyllata) as Potential Anticarcinogenic Agents
Bioassay-directed fractionation of clove terpenes from the plant Eugenia caryophyllata has led to the isolation of the following five active known compounds: beta-caryophyllene [1], beta-caryophyllene oxide [2], alpha-humulene [3], alpha-humulene epoxide I [4], and eugenol [5]. Their structures were determined on the basis of spectral analysis (hreims,
Guo-Qiang Zheng +2 more
semanticscholar +4 more sources
Plant lignans constitute an important group of polyphenols, which have been demonstrated to significantly induce cancer cell death and suppress cancer cell proliferation with minimal toxicity against non-transformed cells. Numerous epidemiological studies have shown that the intake of lignans is associated with lower risk of several cancers.
Sayeh Mottaghi, Hassan Abbaszadeh
semanticscholar +4 more sources
Recent studies have demonstrated that nitroso chemical carcinogens markedly activate guanylate cyclase, which catalyzes the production of guanosine 3',5'-monophosphate (cyclic GMP). We therefore examined the effect of inhibitors of carcinogenic compounds on guanylate cyclase activation by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
万里子 秋山
semanticscholar +5 more sources
Searches for the natural compounds that determine the anticarcinogenic properties of a cruciferous-vegetable diet, revealed the products of alkaloid glucobrassicin biotransformations; among these, ascorbigen, an indole-containing derivative of L-ascorbic acid, was found to be the most abundant.
M. N. Preobrazhenskaya +3 more
semanticscholar +4 more sources
Immunologic Unresponsiveness Induced by Anticarcinogenic Agents and Steroid Hormone
Yoshimi Okada +3 more
semanticscholar +4 more sources
Comparison of 3 Upper Tract Anticarcinogenic Agent Delivery Techniques in an Ex Vivo Porcine Model
To evaluate the degree of urothelial exposure using 3 upper tract delivery techniques in an ex vivo porcine model, to determine the optimal modality to locally deliver topical anticarcinogenic agents in patients with upper tract urothelial carcinoma.An indigo carmine solution was infused into en bloc porcine urinary tracts to test the 3 techniques ...
Matthew Pollard +7 more
openalex +3 more sources
Implications of DNA-acting Agents as Anticarcinogenic Potential in Breast Cancer Therapeutics
Breast cancer is the most prevalent neoplasm diagnosed in women worldwide. There are many factors responsible for breast cancer susceptibility. Mutation in tumor suppressor genes BRCA1 and BRCA2 predispose women to the early onset of breast cancer.
Lovely Sinha, Ujjwal Kumar
openalex +2 more sources

