Results 81 to 90 of about 9,682 (179)

Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole-3-carbinol-Certain health supplements may cause both carcinogenic and anticarcinogenic effects [PDF]

Carcinogenesis, 2002
Stoner et al. (1) described a multi-organ rat model, following earlier work (2,3), and analyzed the effects of indole-3carbinol (I-3-C) on 7,12-dimethylbenz[a]anthracene (DMBA)-, azoxymethane (AOM)and aflatoxin B1 (AFB1)-induced tumor development in colon, mammary gland and liver.
openaire   +1 more source

PLGA-based herb Toosendanin delivery system for efficient therapy of oral squamous cell carcinoma

BMC Complementary Medicine and Therapies
Oral squamous cell carcinoma (OSCC) is a significant public health issue worldwide. Conventional chemotherapeutic agents do not adequately meet the treatment demands because of their low efficacy and adverse side effects.
Lingling Chen, Cheng Feng, Zhenyu Shi, Jianzhe Wang, Tao Wang, Yibing Wang, Lisong Lin, Ye Wu   +7 more
doaj   +1 more source

Antioxidant and Anti-Breast Cancer from Uncaria gambir Roxb Leaves: In Silico & In Vitro Study

Majalah Obat Tradisional
Uncaria gambir Roxb (URG) is one of the plants from West Kalimantan predicted to contain antioxidant and anti-breast cancer. This study aims to test the antioxidant and anti-breast cancer potential.
Dodi Iskandar, Rollando Rollando, Susana Susana, Suharyani Amperawati, Y Erning Indrastuti, Muhammad Hilmi Afthoni   +5 more
doaj   +1 more source

Regulation of Autophagy by Non-Steroidal Anti-Inflammatory Drugs in Cancer

Cancer Management and Research, 2020
Xiangjie Fu,1 Tan Tan,2 Peijun Liu3 1Cholestatic Liver Diseases Center and Department of Gastroenterology, Southwest Hospital, Third Military Medical University, Chongqing, People’s Republic of China; 2Translational Medicine Institute, The First ...
Fu X, Tan T, Liu P
doaj  

Analysis of the Phytochemical Composition of Papaya Root (Carica papaya L.) and Its Potential as an Anticarcinogenic Agent: A Preliminary Study

Glosains: Jurnal Sains Global Indonesia
Background: Cancer remains a major global health problem with high morbidity and mortality. Conventional treatments often cause serious side effects and require high costs, encouraging the exploration of natural products as alternative anticarcinogenic agents. Carica papaya L.
Shabila Rizka Azzahra, Elman Boy, Yulia Afrina Nasution   +2 more
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Can Mecsina Hemostopper, which has a Cytotoxic Effect on Mcf-7 Cells, be Considered an Anticarcinogenic Agent due to its Immunological Properties?

Medical Records
Aim: Mecsina is used as a hemostatic agent such as Ankaferd and Tranexamic acid. To struggle with breast cancer, which is a serious public health issue, new, effective, and less toxic therapeutic agents are needed. Hence, it is aimed to compare and evaluate the effects of Mecsina and Ankaferd, both of which contain natural biomolecules in their ...
Mustafa ÇİÇEK, Mehmet Kemal TÜMER, Alpgiray TURGUT   +2 more
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Inhibition of MMP-2 and MMP-9 by Dietary Antioxidants in THP-1 Macrophages and Sera from Patients with Breast Cancer

Molecules
Polyphenols, the main antioxidants of diet, have shown anti-inflammatory, antioxidant and anticarcinogenic activities. Here, we compared the effects of four polyphenolic compounds on ROS production and on the levels of matrix metalloproteinase (MMP)-2 ...
Tiziana Latronico, Tania Petraglia, Carmela Sileo, Domenico Bilancia, Rocco Rossano, Grazia Maria Liuzzi   +5 more
doaj   +1 more source

3-1) Usefulness of Medium-Term Bioassay Determining Formations of Pulmonary Adenoma in NIH (GP) Mice for Finding Anticarcinogenic Agents from Natural Products

The Journal of Toxicological Sciences, 1991
Various long-term bioassay methods have been used to determine the carcinogenicity of chemical substances. Among them, a long-term method developed by Toth (1968), which scores the incidence of pulmonary adenoma formation at 28 to 56 weeks following subcutaneous administration of chemical carcinogens to new-born mice is used widely.
openaire   +2 more sources

Investigation of antioxidant, antimicrobial, cytotoxic, wound-healing properties, bio element levels and phytochemical profiles of aqueous extracts of Verbascum splendidum leaf and aboveground parts. [PDF]

BMC Complement Med Ther
Büyükben A.
europepmc   +1 more source

Investigation on the Cytotoxicity of Hydroxycinnamic and Hydroxybenzoic Acid-Based Natural Antioxidant Conjugated Terpyridine Analogues toward Triple-Negative Breast Cancer. [PDF]

ACS Med Chem Lett
Roy A, Beniwal N, Shome A, Rengan AK, Chinta JP.   +4 more
europepmc   +1 more source