Results 51 to 60 of about 11,626 (181)

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

open access: yesChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci   +5 more
wiley   +1 more source

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

open access: yesAdvanced Science, Volume 13, Issue 26, 8 May 2026.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He   +18 more
wiley   +1 more source

Molecular Stratification of Antiphospholipid Syndrome Through Integrative Analysis of the Whole‐Blood RNA Transcriptome

open access: yesArthritis &Rheumatology, Volume 78, Issue 5, Page 1124-1133, May 2026.
Objective Antiphospholipid syndrome (APS) is a thromboinflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)–positive patients using whole‐blood transcriptomics.
Amala Ambati   +13 more
wiley   +1 more source

Anticardiolipin antibody in recurrent spontaneous aborting and fertile women

open access: yesSão Paulo Medical Journal
OBJECTIVE: To determine the association between the presence of anticardiolipin antibody and a history of recurrent spontaneous abortion. STUDY DESIGN: clinical controlled study LOCATION: Department of Gynecology and Obstetrics - University of Campinas ...
Egle Couto   +4 more
doaj   +1 more source

A case of pulmonary tuberculosis presenting as diffuse alveolar haemorrhage: is there a role for anticardiolipin antibodies?

open access: yesBMC Infectious Diseases, 2010
Background Diffuse alveolar haemorrhage (DAH) has been rarely reported in association with pulmonary infections. Case Presentation We report the case of a 43 year old immunocompetent man presenting with dyspnoea, fever and haemoptysis.
Lauria Francesco N   +4 more
doaj   +1 more source

Thrombembolic events in patients with non-hodgkin's lymphoma And anticardiolipin antibodies

open access: yesHematology Reports, 2020
Patients with non-Hodgkin's lymphoma (NHL) have an increased risk of thromboembolic events. It is important to identify NHL patients at increased risk of developing thromboembolic complications in order to apply prophylactic treatment.
S. Buruiana   +3 more
doaj  

Gestation in patients with high levels of anticardiolipin antibodies, a history of deep venous thrombosis and miscarriages

open access: yesArchives of Medical Science, 2006
The aim is to stress the importance of prophylaxis against deep venous thrombosis in gravidas with high levels of anticardiolipin antibodies with or without a history of repetitive miscarriages.
José Maria Pereira de Godoy   +4 more
doaj  

Advances in the Research on Anticardiolipin Antibody

open access: yesJournal of Immunology Research, 2019
Anticardiolipin antibody (ACA) is a kind of autoantibody and is one of the antiphospholipid antibodies (aPLs). Phospholipids with a negative charge on platelets and endothelial cell membranes are ACA target antigens.
Dan Wang   +3 more
doaj   +1 more source

Incidence of Anticardiolipin Antibodies Level in Patients with Recurrent Abortion

open access: yesDiyala Journal of Medicine, 2019
Background: Antiphospholipid syndrome is a major reproductive complication in women, that is characterized by recurrent abortion, thrombosis and thrombocytopenia in association with antiicardiolipin antibodies .
Farhan A. Risan
doaj   +2 more sources

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