Results 141 to 150 of about 40,585 (248)

Improving Medication Management in Indonesian Aged Care Homes: Research Priority Setting With Stakeholders

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Indonesia and other Southeast Asian nations are experiencing rapidly aging populations. The Indonesian Government recently announced a national initiative of aged care homes to support older people not able to live independently or receive family care.
Yulisna Mutia Sari, J. Simon Bell, Surya Adhi, Uswa Alhamid, Esthika Dewiasty, Annisa Dhanira, Clara M. Kusharto, Evi Dwi Novriany, Dion Notario, Imran Pambudi, Rocksy Situmeang, Sri Soenarti, M. Rizky Widodo, Grace Wangge   +13 more
wiley   +1 more source

Japanese Anticholinergic Risk Scale and Domain-Specific Functional Outcomes in Older Poststroke Patients. [PDF]

Geriatr Gerontol Int
Matsumoto A, Yoshimura Y.
europepmc   +1 more source

Dualsteric and dual‐acting modulation of muscarinic receptors by antagonist KH‐5

British Journal of Pharmacology, Volume 183, Issue 19, Page 5769-5790, October 2026.
Abstract Background and purpose Muscarinic acetylcholine receptors are key therapeutic targets, and ligands engaging both orthosteric and allosteric sites may offer improved selectivity and efficacy. Here, we investigated whether the muscarinic antagonist KH‐5 acts as a dualsteric antagonist and defined its mode of interaction with muscarinic receptors.
Alena Janoušková‐Randáková, Eva Dolejší, Nikolai Chetverikov, Jan Jakubík   +3 more
wiley   +1 more source

Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm

British Journal of Pharmacology, Volume 183, Issue 19, Page 5701-5731, October 2026.
Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley   +1 more source

Prevalence of Psychotropic Use and Psychotropic Polypharmacy in a Finnish National Cohort of Persons With Intellectual Disabilities

Journal of Intellectual Disability Research, Volume 70, Issue 10, Page 1112-1124, October 2026.
ABSTRACT Background Psychotropic use and psychotropic polypharmacy are common in people with intellectual disabilities, but representative population‐based studies on this topic are scarce. We evaluated the prevalence of psychotropic use and psychotropic polypharmacy in a Finnish nationwide cohort of people with intellectual disabilities aged 0–97 ...
Ville Virtanen, Leena Saastamoinen, Maria Arvio, Hannu T. Vesala, Sonja Miettinen, Antti Teittinen, Anna‐Maija Tolppanen   +6 more
wiley   +1 more source

The Feasibility and Acceptability of a Collaborative Deprescribing Intervention to Reduce Anticholinergic Burden Among Hospitalised Older Patients. [PDF]

Basic Clin Pharmacol Toxicol
Ibrahim K, Radcliffe E, Hewertson E, Bates A, Fox A, Smith E, Mckenzie C, Jones L, Mckelvie S, Kandala NI, McCloskey S, Sach T, Lim S.   +12 more
europepmc   +1 more source

ANTICHOLINERGIC PREMEDICATION

British Journal of Anaesthesia, 1979
openaire   +2 more sources

Editorial: Deprescribing and Minimizing Use of Anticholinergic Medications

Frontiers in Pharmacology, 2021
Roy L. Soiza, Malaz A. Boustani, Noll L. Campbell, Arduino A. Mangoni   +3 more
doaj   +1 more source

Correction: Anticholinergic burden and health‑related quality of life among adult patients in a resource‑limited setting: a cross‑sectional study. [PDF]

Int J Clin Pharm
Gebreyohannes EA, Shibe BS, Taye WA, Lee K, Abdela OA, Ayele EM, Belachew EA, Mengistu SB, Myint PK, Soiza RL.   +9 more
europepmc   +1 more source

Anticholinergic burden in older adults

Introduction The world’s older population, often defined as people aged ≥65, is growing rapidly. With advancing age, there is an increased likelihood of adverse effects from medicines.

core   +1 more source