Results 51 to 60 of about 83,224 (354)

Anticholinergic drugs and risk of dementia: case-control study

British medical journal, 2018
Objectives To estimate the association between the duration and level of exposure to different classes of anticholinergic drugs and subsequent incident dementia. Design Case-control study.
K. Richardson, C. Fox, I. Maidment, N. Steel, Y. Loke, A. Arthur, P. Myint, Carlota M. Grossi, K. Mattishent, K. Bennett, N. Campbell, M. Boustani, L. Robinson, C. Brayne, F. Matthews, G. Savva   +15 more
semanticscholar   +1 more source

Anticholinergic Exposure During Rehabilitation: Cognitive and Physical Function Outcomes in Patients with Delirium Superimposed on Dementia [PDF]

, 2015
OBJECTIVES: We examined the association between anticholinergic medication exposure and subsequent cognitive and physical function in patients with delirium superimposed on dementia during rehabilitation.
Behrens, Liza, Boustani, Malaz, Campbell, Noll, Clare, Linda, Colancecco, Elise, Fick, Donna M., Hill, Nikki, Kolanowski, Ann, Mogle, Jacqueline, Mulhall, Paula   +9 more
core   +1 more source

Quality of anticholinergic burden scales and their impact on clinical outcomes: a systematic review

European Journal of Clinical Pharmacology, 2020
Older people are at risk of anticholinergic side effects due to changes affecting drug elimination and higher sensitivity to drug’s side effects. Anticholinergic burden scales (ABS) were developed to quantify the anticholinergic drug burden (ADB). We aim
Angela Lisibach, Valérie Benelli, M. Ceppi, K. Waldner-Knogler, C. Csajka, M. Lutters   +5 more
semanticscholar   +1 more source

The Influence of Patient Characteristics on Anticholinergic Events in Older People

Dementia and Geriatric Cognitive Disorders Extra, 2016
Aims: To examine patient characteristics that predict adverse anticholinergic-type events in older people. Methods: This retrospective population-level study included 2,248 hospitalised patients.
Mohammed Saji Salahudeen, Prasad S. Nishtala, Stephen B. Duffull   +2 more
doaj   +1 more source

Anticholinergic drugs and incident dementia, mild cognitive impairment and cognitive decline: a meta-analysis

Age and Ageing, 2020
Background the long-term effect of the use of drugs with anticholinergic activity on cognitive function remains unclear. Methods we conducted a systematic review and meta-analysis of the relationship between anticholinergic drugs and risk of dementia ...
Nina T. Pieper, Carlota M. Grossi, Wei-Yee Chan, Y. Loke, G. Savva, Clara Haroulis, N. Steel, C. Fox, I. Maidment, A. Arthur, P. Myint, T. Smith, L. Robinson, F. Matthews, C. Brayne, K. Richardson   +15 more
semanticscholar   +1 more source

Clozapine, Fluoxetine, and Benztropine- associated Ileus: Case Report [PDF]

, 2007
Gastrointestinal complications of anticholinergic medications are prevalent, potentially life-threatening, and could be more actively prevented. We present a case report of an ileus that required surgical intervention and developed in the context of ...
Bourgeois, James A., O.D., M.D., Pajouhi, Pegah, M.D. (PGY1)   +1 more
core   +2 more sources

An Evidence-Based Update on Anticholinergic Use for Drug-Induced Movement Disorders

CNS Drugs
Drug-induced movement disorders (DIMDs) are associated with use of dopamine receptor blocking agents (DRBAs), including antipsychotics. The most common forms are drug-induced parkinsonism (DIP), dystonia, akathisia, and tardive dyskinesia (TD).
Nora Vanegas-Arroyave, Stanley N Caroff, L. Citrome, Jovita Crasta, R. McIntyre, Jonathan M Meyer, Amita R Patel, J. M. Smith, Khody Farahmand, Rachel Manahan, L. Lundt, Samantha A. Cicero   +11 more
semanticscholar   +1 more source

Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease

Respiratory Research, 2011
Background The long-term efficacy and safety of aclidinium bromide, a novel, long-acting muscarinic antagonist, were investigated in patients with moderate to severe chronic obstructive pulmonary disease (COPD).
Bateman Eric D, Donohue James F, Fabbri Leonardo, Magnussen Helgo, Chanez Pascal, Agusti Alvar, Jones Paul W, Rennard Stephen I, Gross Nicholas J, Lamarca Rosa, Caracta Cynthia, Gil Esther   +11 more
doaj   +1 more source

Cost–effectiveness of overactive bladder treatments from a US commercial and payer perspective

Journal of Comparative Effectiveness Research, 2023
Aim: The cost–effectiveness of treatment options (anticholinergics, β3-adrenoceptor agonists, onabotulinumtoxinA, sacral nerve stimulation and percutaneous tibial stimulation [the latter two including new rechargeable neurostimulators]) for the ...
Brian Murray, Jennifer Miles-Thomas, Amy J Park, Victor B Nguyen, Amy Tung, Patrick Gillard, Anjana Lalla, Victor W Nitti, Christopher J Chermansky   +8 more
doaj   +1 more source

Associations Between Anticholinergic Medication Exposure and Adverse Health Outcomes in Older People with Frailty: A Systematic Review and Meta-analysis

Drugs - Real World Outcomes, 2021
There are robust associations between use of anticholinergic medicines and adverse effects in older people. However, the nature of these associations for older people living with frailty is yet to be established. The aims were to identify and investigate
D. Mehdizadeh, M. Hale, O. Todd, H. Zaman, I. Marques, D. Petty, David P Alldred, O. Johnson, M. Faisal, Peter H Gardner, A. Clegg   +10 more
semanticscholar   +1 more source