Results 1 to 10 of about 322,983 (366)

Anticoagulant activity of a synthetic heparinoid in relation to molecular weight and N-sulfate content [PDF]

open access: yes, 1981
Addition of chlorosulfonyl isocyanate to C=C bonds in cis-1,4-polyisoprene and reaction of the adduct with NaOH resulted in the formation of a water-soluble polyelectrolyte with N-sulfate and carboxylate groups.
Beugeling   +13 more
core   +16 more sources

Antiviral anticoagulation [PDF]

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel envelope virus that causes coronavirus disease 2019 (COVID-19). Hallmarks of COVID-19 are a puzzling form of thrombophilia that has elevated D-dimer but only modest effects on other parameters of coagulopathy.
Pryzdial, Edward L. G.   +3 more
openaire   +3 more sources

Verification of selective and individual pulmonary thromboembolism prophylaxes for cesarean delivery [PDF]

open access: yesObstetrics & Gynecology Science, 2023
Objective This study aimed to verify the utility of simple, safe, and effective venous thromboembolism (VTE) prophylaxis and implement it with few adverse events during cesarean delivery.
Ryuji Kawaguchi   +5 more
doaj   +1 more source

Optimizing Warfarin Dosing using Deep Reinforcement Learning [PDF]

open access: yesJournal of Biomedical Informatics, 137 (2023) 104267, 2022
Warfarin is a widely used anticoagulant, and has a narrow therapeutic range. Dosing of warfarin should be individualized, since slight overdosing or underdosing can have catastrophic or even fatal consequences. Despite much research on warfarin dosing, current dosing protocols do not live up to expectations, especially for patients sensitive to ...
arxiv   +1 more source

Necrotizing Pancreatitis: To Anticoagulate or Not to Anticoagulate?

open access: yesCureus, 2022
Necrotizing pancreatitis is an inflammatory process that poses a strong risk of systemic venous thromboembolism. However, it is often challenging to opt for systemic anticoagulation since the disease is also associated with an increased risk of hemorrhage.
Abi-Saleh, Simon P   +3 more
openaire   +1 more source

Anticoagulants and Osteoporosis [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Anticoagulant agents are widely used in the treatment of thromboembolic events and in stroke prevention. Data about their effects on bone tissue are in some cases limited or inconsistent (oral anti-vitamin K agents), and in others are sufficiently strong (heparins) to suggest caution in their use in subjects at risk of osteoporosis.
Signorelli S. S.   +5 more
openaire   +3 more sources

Concomitant Use of Single Antiplatelet Therapy With Edoxaban or Warfarin in Patients With Atrial Fibrillation: Analysis From the ENGAGE AF‐TIMI48 Trial

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundWe studied the concomitant use of single antiplatelet therapy (SAPT) on the efficacy and safety of the anti‐Xa agent edoxaban in patients with atrial fibrillation (AF). Methods and ResultsENGAGE AF‐TIMI 48 was a randomized trial that compared 2
Haiyan Xu   +9 more
doaj   +1 more source

In vivo examination of the anticoagulant effect of the Brassica oleracea methanol extract [PDF]

open access: yesArchives of Biological Sciences, 2015
The anticoagulant effect of the methanol extract of Brassica oleracea var. capitata (MEB) was examined in rabbits. The animals were divided into five groups, each comprising seven animals.
Khan Rafeeq Alam   +3 more
doaj   +1 more source

Shear viscosity and nonlinear behaviour of whole blood under large amplitude oscillatory shear [PDF]

open access: yes, 2013
We investigated experimentally the rheological behavior of whole human blood subjected to large amplitude oscillatory shear under strain control to assess its nonlinear viscoelastic response.
Alves, M.A.   +6 more
core   +1 more source

Synthesis and in Vitro and in Vivo Anticoagulant and Antiplatelet Activities of Amidino- and Non-Amidinobenzamides

open access: yesMolecules, 2016
Three amidino- and ten non-amidinobenzamides were synthesized as 3-aminobenzoic acid scaffold-based anticoagulant and antiplatelet compounds. The anticoagulant activities of thirteen synthesized compounds 1–13, and 2b and 3b as prodrugs were preliminary ...
Soo Hyun Lee   +3 more
doaj   +1 more source

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