Results 11 to 20 of about 189,241 (266)
International Journal of Medical Toxicology and Forensic Medicine, 2020 Background: The Novel Oral Anticoagulants (NOACs), despite numerous benefits, such as the ease of use and less drug involvement, provide extensive adverse effects.
Abbas Ghaysouri +2 more
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Journal of Pharmacy and Pharmacology, 1949 Abstract The processes that underly the clotting of blood are still far from adequately understood, in spite of the many facts uncovered by generations of patient investigators. The classical scheme associated with the name of Morawitz1, although neither complete nor universally accepted, is still useful as a summary of the main events ...
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Heparin Mimetics: Their Therapeutic Potential
Pharmaceuticals, 2017 Heparin mimetics are synthetic and semi-synthetic compounds that are highly sulfated, structurally distinct analogues of glycosaminoglycans. These mimetics are often rationally designed to increase potency and binding selectivity towards specific ...
Shifaza Mohamed, Deirdre R. Coombe
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Veterinary and Animal Science, 2020 Vitamin K epoxide reductase (VKOR) is a target enzyme for anticoagulants, such as warfarin, that are used as medicines or rodenticides. Assessing VKOR activity is required to ensure the proper usage of these drugs.
Kazuki Takeda +4 more
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Life‐threatening extrapleural hematoma in an anticoagulated patient 2 weeks after lobectomy
Thoracic Cancer, 2021 We report a case of an anticoagulated patient with sudden onset pleural hematoma after straining at defecation to cardiac arrest on 2 weeks after lobectomy for lung cancer.
Masanori Shimomura +3 more
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Molecular Therapy: Nucleic Acids, 2017 The long blood circulatory property of human serum albumin, due to engagement with the cellular recycling neonatal Fc receptor (FcRn), is an attractive drug half-life extension enabling technology. This work describes a novel site-specific albumin double-
Matthias Kuhlmann +12 more
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Lung India, 2021 Hemostatic derangement is a hallmark in severe COVID-19. Markedly elevation of D-dimer and fibrinogen degradation product levels were observed in patients with severe COVID-19 higher and 71.4% of nonsurvivors met the International Society of Thrombosis ...
Ka U Lio, Parth Rali
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Venous thromboembolism in COVID 19 infection: Prevalence and practice of prophylaxis - A narrative
Indian Journal of Vascular and Endovascular Surgery, 2021 The aims of this review are to ascertain the true prevalence of venous thromboembolism (VTE) in critically ill COVID 19 patients, to explore the strategy regarding prophylaxis and whether intensified prophylaxis is required for critically ill patients ...
U Vasudeva Rao, M D Wasim
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Pharmacogenetics of Anticoagulants [PDF]
Human Genomics and Proteomics, 2010 Warfarin, acenocoumarol, and phenprocoumon are among the major anticoagulant drugs worldwide. Because of their low therapeutic index and serious adverse reactions (ADRs), their wide use, and their varying kinetics and pharmacogenetic dependence, it is of great importance to explore further possibilities to forecast the dose beyond conventional INR ...
Rane, Anders, Lindh, Jonatan D.
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Anticoagulant Rodenticides, Islands and Animal Welfare Accountancy
Animals, 2019 Anticoagulant rodenticides are used to manage rodents in domestic, municipal, agricultural, and conservation settings. In mammals and birds, anticoagulant poisoning causes extensive hemorrhagic disruption, with the primary cause of death being severe ...
Penny Fisher +3 more
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