Results 191 to 200 of about 346,610 (333)

Oral anticoagulant reversal and mortality in trauma patients: a multicentre propensity score-matched cohort study. [PDF]

open access: yesEClinicalMedicine
Lang E   +17 more
europepmc   +1 more source

Design, Synthesis, and Molecular Docking of Triazole‐Coumarin Hybrids as Potent Breast Cancer Inhibitors Targeting Cell Cycle and Apoptosis

open access: yesChemistry &Biodiversity, EarlyView.
Triazole‐coumarin hybrids were synthesized as breast cancer inhibitors. Derivative 5f induced S‐phase arrest and apoptosis in cancer cells, with minimal toxicity to healthy cells, showing promise for anticancer drug development. ABSTRACT Breast cancer continues to pose a significant global health burden, highlighting the urgent need for novel ...
Murat Keser   +4 more
wiley   +1 more source

Glycosaminoglycans as Polyelectrolytes: Charge, Interactions, and Applications

open access: yesChemBioChem, EarlyView.
Glycosaminoglycans (GAGs) are linear, anionic biopolymers with their functions tightly linked to their charge. This review approaches GAGs from a polyelectrolyte perspective, shedding light on how the distribution of sulfate groups and, thus, negative charges, governs their interactions with other biomolecules.
Gergo Peter Szekeres   +7 more
wiley   +1 more source

A Novel Cardiac Computed Tomography‐Based Calcium Scoring System for Predicting the Use of Atherectomy Devices in Severely Calcified Coronary Lesions

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Cardiac computed tomography (CT) is a well‐established process used to diagnose coronary artery disease; however, its specific advantages in predicting the use of atherectomy devices during percutaneous coronary intervention (PCI) for moderate to severe calcified lesions remain to be determined.
Yasuhiro Nakano   +19 more
wiley   +1 more source

Coronary Ectasia and ST Elevation Myocardial Infarction Patients: Does Atherosclerosis Influence Periprocedural Management and Long‐Term Prognosis?

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary artery ectasia (CAE) influences procedural outcomes in the context of ST‐elevation myocardial infarction (STEMI); however, its relationship with atherosclerotic coronary artery disease (ACAD) remains unclear. Aims This study aimed to compare clinical and procedural characteristics, as well as outcomes, in patients with ...
Victorine Fraichot   +6 more
wiley   +1 more source

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