Results 151 to 160 of about 156,819 (199)

The anticoagulant activity of dermatan sulphates

Thrombosis Research, 1980
Abstract The possible role of antithrombin III (AT III) in the ex vivo anticoagulant activity of dermatan sulphates was examined using four preparations of the glycosaminoglycan and normal and AT III-deficient plasmas. Two of the preparations, like heparin, were less potent anticoagulants in deficient plasma than in normal plasma.
W F, Long, F B, Williamson, G, Kindness, M, Edward   +3 more
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Anticoagulant activity of a bacterial glycopeptide

Thrombosis Research, 1990
The anticoagulant properties of myxalin, a glycopeptide secreted by a Gram negative bacterium strain (Myxococcus xanthus) are studied and compared to those of heparin. This soluble material exhibits an anticoagulant activity which implies the inhibition of some serine proteases, thrombin and factor Xa.
A, Akoum, J, Josefonvicz, M, Sigot
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Anticoagulant Activity and Mechanism of Non-Anticoagulant Sulfated Polysaccharides

Blood, 2011
Abstract Abstract 1208 Fucoidans are sulfated polysaccharides which are extracted from brown seaweeds and echinoderms and have a wide variety of biological activities. Described as non-anticoagulant polysaccharides (NASPs), they have been demonstrated to improve clotting in FVIII- and FIX-deficient plasma (Liu et al., 2006)
Michael Dockal, Susanne Till, Sabine Knappe, Hartmut J. Ehrlich, Friedrich Scheiflinger   +4 more
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Anticoagulant activities of lung and mucous heparins

Thrombosis Research, 1978
Abstract It is generally assumed that heparins prepared from different tissues have equivalent actions. However, significant differences were found between lung and mucosal heparins when they were examined in an anti-Factor Xa assay, both in vivo and in vitro . These differences were not seen when the heparins were assayed by an APTT assay.
T W, Barrowcliffe, E A, Johnson, C A, Eggleton, D P, Thomas   +3 more
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Mechanisms of activity of lupus anticoagulants

Current Opinion in Hematology, 1997
Lupus anticoagulants comprise a heterogenous group of circulating immunoglobulins that are associated with an increased risk of thrombosis. It was believed earlier that these antibodies were directed against anionic phospholipids. Recent findings, however, establish that the autoantibodies in lupus anticoagulants are not directed against "native ...
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Antiplatelet, anticoagulant, and profibrinolytic activities of withaferin A

Vascular Pharmacology, 2014
Withaferin A (WFA), an active compound from Withania somnifera, is widely researched for its anti-inflammatory, cardioactive and central nervous system effects. However, antiplatelet, anticoagulant, and profibrinolytic properties of WFA have not been studied.
Sae-Kwang, Ku, Jong-Sup, Bae
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Anticoagulant activity of sulfoalkyl derivatives of curdlan

Archives of Pharmacal Research, 2001
Curdlan is a natural beta-1,3-glucan produced by Agrobacterium biovar 1. In this study, the anticoagulant activity of sulfoalkyl derivatives of curdlan was investigated by carrying out activated partial thromboplastin time (APTT) assay and compared with that of o-sulfonated curdlan.
K B, Lee, J H, Bae, J S, Kim, Y C, Yoo, B S, Kim, S T, Kwak, Y S, Kim   +6 more
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Antiplatelet, anticoagulant, and profibrinolytic activities of cudratricusxanthone A

Archives of Pharmacal Research, 2013
Cudratricusxanthone A (CTXA), a natural bioactive compound extracted from the roots of Cudrania tricuspidata Bureau, is known to possess hepatoprotective, antiproliferative and anti-inflammatory activities. However, antiplatelet, anticoagulant, and profibrinolytic properties have not been studied.
Hayoung, Yoo, Sae-Kwang, Ku, Wonhwa, Lee, Soyoung, Kwak, Young-Doo, Baek, Byung-Woon, Min, Gil-Saeng, Jeong, Jong-Sup, Bae   +7 more
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Anticoagulant activity of select dietary supplements

Nutrition Reviews, 2012
This review considers the potential of certain dietary supplements, including garlic, Ginkgo biloba, ginger, ginseng, fish oil, and vitamin E, to interfere with hemostasis. Dietary supplements are common components of the diet in the United States, with about half the US adult population taking some type of dietary supplement regularly.
Michael J, Stanger, Lauren A, Thompson, Andrew J, Young, Harris R, Lieberman   +3 more
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Sulfated polysaccharides and their anticoagulant activity: A review

Applied Biochemistry and Microbiology, 2010
Published data on the sulfated polysaccharides of various origins that display an anticoagulant activity are summarized and analyzed. The methods used for producing semisynthetic derivatives are considered. A key role of the polysaccharide structure in the mechanisms of specific interaction with various blood plasma proteinases is discussed.
N M, Mestechkina, V D, Shcherbukhin
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