Results 151 to 160 of about 6,300,141 (198)

Effects of anticoagulants on the activity of gelatinases

Clinical Biochemistry, 2007
To identify the best procedure for preanalytical blood collection in the determination of matrix metalloproteinase (MMP)-2 and -9 by testing the effects of anticoagulants on their activity.Active forms of both gelatinases were measured by specific activity assay systems in serum, plasma EDTA, plasma-heparin and plasma-citrate obtained from 20 healthy ...
CASTELLAZZI, Massimiliano, TAMBORINO, Carmine, FAINARDI, Enrico, MANFRINATO, Maria Cristina, GRANIERI, Enrico Gavino Giuseppe, DALLOCCHIO, Franco Pasquale Filippo, BELLINI, Tiziana   +6 more
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THE ANTITHYROID ACTIVITY OF THE ANTICOAGULANT PHENYLINDANEDIONE

Journal of Endocrinology, 1961
SUMMARY 1. The anticoagulant drug phenylindanedione (PID) reduced the uptake of 131I by the rat thyroid as effectively as propylthiouracil (PTU) in a dosage of 0·3 m-mole/kg body weight. The effect of PID lasted for a shorter time, and at smaller doses PTU was much more effective than PID. 2.
E D, WILLIAMS, I, DONIACH
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Anticoagulant activities of persicarin and isorhamnetin

Vascular Pharmacology, 2013
Persicarin and isorhamnetin were isolated from Oenanthe javanica and their anticoagulant activities were examined by monitoring activated partial thromboplastin time (aPTT), prothrombin time (PT), and the activities of cell-based thrombin and activated factor X (FXa).
Sae-Kwang, Ku, Tae Hoon, Kim, Jong-Sup, Bae   +2 more
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The anticoagulant activity of dermatan sulphates

Thrombosis Research, 1980
Abstract The possible role of antithrombin III (AT III) in the ex vivo anticoagulant activity of dermatan sulphates was examined using four preparations of the glycosaminoglycan and normal and AT III-deficient plasmas. Two of the preparations, like heparin, were less potent anticoagulants in deficient plasma than in normal plasma.
W F, Long, F B, Williamson, G, Kindness, M, Edward   +3 more
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Anticoagulant activity of a bacterial glycopeptide

Thrombosis Research, 1990
The anticoagulant properties of myxalin, a glycopeptide secreted by a Gram negative bacterium strain (Myxococcus xanthus) are studied and compared to those of heparin. This soluble material exhibits an anticoagulant activity which implies the inhibition of some serine proteases, thrombin and factor Xa.
A, Akoum, J, Josefonvicz, M, Sigot
openaire   +2 more sources

Mechanisms of activity of lupus anticoagulants

Current Opinion in Hematology, 1997
Lupus anticoagulants comprise a heterogenous group of circulating immunoglobulins that are associated with an increased risk of thrombosis. It was believed earlier that these antibodies were directed against anionic phospholipids. Recent findings, however, establish that the autoantibodies in lupus anticoagulants are not directed against "native ...
openaire   +2 more sources

Anticoagulant Activity and Mechanism of Non-Anticoagulant Sulfated Polysaccharides

Blood, 2011
Abstract Abstract 1208 Fucoidans are sulfated polysaccharides which are extracted from brown seaweeds and echinoderms and have a wide variety of biological activities. Described as non-anticoagulant polysaccharides (NASPs), they have been demonstrated to improve clotting in FVIII- and FIX-deficient plasma (Liu et al., 2006)
Michael Dockal, Susanne Till, Sabine Knappe, Hartmut J. Ehrlich, Friedrich Scheiflinger   +4 more
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Anticoagulant activities of lung and mucous heparins

Thrombosis Research, 1978
Abstract It is generally assumed that heparins prepared from different tissues have equivalent actions. However, significant differences were found between lung and mucosal heparins when they were examined in an anti-Factor Xa assay, both in vivo and in vitro . These differences were not seen when the heparins were assayed by an APTT assay.
T W, Barrowcliffe, E A, Johnson, C A, Eggleton, D P, Thomas   +3 more
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Antiplatelet, anticoagulant, and profibrinolytic activities of withaferin A

Vascular Pharmacology, 2014
Withaferin A (WFA), an active compound from Withania somnifera, is widely researched for its anti-inflammatory, cardioactive and central nervous system effects. However, antiplatelet, anticoagulant, and profibrinolytic properties of WFA have not been studied.
Sae-Kwang, Ku, Jong-Sup, Bae
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Anticoagulant activity and pleiotropic effects of heparin

JMV-Journal de Médecine Vasculaire, 2020
The recognized therapeutic effect of heparins is an anticoagulant activity (anti-Xa and anti-IIa) acting in an indirect manner (cofactor of antithrombin) but which is carried by only 20% at best of the glycan chains composing any commercial preparation of heparin, whether unfractionated or low molecular weight.
C, Bal Dit Sollier, J-G, Dillinger, L, Drouet   +2 more
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