Results 161 to 170 of about 6,300,141 (198)

Anticoagulant activity of sulfoalkyl derivatives of curdlan

Archives of Pharmacal Research, 2001
Curdlan is a natural beta-1,3-glucan produced by Agrobacterium biovar 1. In this study, the anticoagulant activity of sulfoalkyl derivatives of curdlan was investigated by carrying out activated partial thromboplastin time (APTT) assay and compared with that of o-sulfonated curdlan.
K B, Lee, J H, Bae, J S, Kim, Y C, Yoo, B S, Kim, S T, Kwak, Y S, Kim   +6 more
openaire   +2 more sources

Antiplatelet, anticoagulant, and profibrinolytic activities of cudratricusxanthone A

Archives of Pharmacal Research, 2013
Cudratricusxanthone A (CTXA), a natural bioactive compound extracted from the roots of Cudrania tricuspidata Bureau, is known to possess hepatoprotective, antiproliferative and anti-inflammatory activities. However, antiplatelet, anticoagulant, and profibrinolytic properties have not been studied.
Hayoung, Yoo, Sae-Kwang, Ku, Wonhwa, Lee, Soyoung, Kwak, Young-Doo, Baek, Byung-Woon, Min, Gil-Saeng, Jeong, Jong-Sup, Bae   +7 more
openaire   +2 more sources

Anticoagulant activity of select dietary supplements

Nutrition Reviews, 2012
This review considers the potential of certain dietary supplements, including garlic, Ginkgo biloba, ginger, ginseng, fish oil, and vitamin E, to interfere with hemostasis. Dietary supplements are common components of the diet in the United States, with about half the US adult population taking some type of dietary supplement regularly.
Michael J, Stanger, Lauren A, Thompson, Andrew J, Young, Harris R, Lieberman   +3 more
openaire   +2 more sources

Sulfated polysaccharides and their anticoagulant activity: A review

Applied Biochemistry and Microbiology, 2010
Published data on the sulfated polysaccharides of various origins that display an anticoagulant activity are summarized and analyzed. The methods used for producing semisynthetic derivatives are considered. A key role of the polysaccharide structure in the mechanisms of specific interaction with various blood plasma proteinases is discussed.
N M, Mestechkina, V D, Shcherbukhin
openaire   +2 more sources

Bioengineered human heparin with anticoagulant activity

Metabolic Engineering, 2016
Heparin is a carbohydrate anticoagulant used clinically to prevent thrombosis, however impurities can limit its efficacy. Here we report the biosynthesis of heparin-like heparan sulfate via the recombinant expression of human serglycin in human cells. The expressed serglycin was also decorated with chondroitin/dermatan sulfate chains and the relative ...
Megan S, Lord, Bill, Cheng, Fengying, Tang, J Guy, Lyons, Jelena, Rnjak-Kovacina, John M, Whitelock   +5 more
openaire   +2 more sources

Anticoagulant and antiheparin activities of a pentosan polysulphate

Thrombosis Research, 1983
Pentosan polysulphate (PPS, Hemoclar, MW 6,700) was observed to have a low affinity for ATIII-Sepharose eluting at 0.3M NaCl. Tested in vitro it had, as previously reported, a low potency as an anticoagulant, about 10 times less than heparin on a weight for weight basis.
M F, Scully, K M, Weerasinghe, V, Ellis, B, Djazaeri, V V, Kakkar   +4 more
openaire   +2 more sources

[The anticoagulant activity of fucoidans].

Eksperimental'naia i klinicheskaia farmakologiia, 1997
The influence of the degree of fucoidan macromolecules sulfation on their ability to induce an anticoagulant effect was studied. In in vitro experiments with the basic stain and in in vivo experiments on rabbits with performance of Quick's test, APTT, and spectrophotometric determination of antithrombin III (AT-III) activity a direct dependence of the ...
E A, Gavrilova, I I, Barbanova, A I, Usov, V S, Efimov, A I, Smirnov   +4 more
openaire   +1 more source

Synthesis of sulfated pectins and their anticoagulant activity

Biochemistry (Moscow), 2010
The following pectins were sulfated: bergenan BC (the pectin of Bergenia crassifolia L), lemnan LM (the pectin of Lemna minor L), and galacturonan as a backbone of pectins. Pyridine monomethyl sulfate, pyridine sulfotrioxide, and chlorosulfonic acid were used as reagents for sulfation.
F V, Vityazev, V V, Golovchenko, O A, Patova, N N, Drozd, V A, Makarov, A S, Shashkov, Yu S, Ovodov   +6 more
openaire   +2 more sources

Anticoagulant activity of dog hookworm

American Journal of Physiology-Legacy Content, 1971
G G, Spellman, H L, Nossel
openaire   +2 more sources

Anticoagulant Activities of Heparin and Fragments

Annals of the New York Academy of Sciences, 1989
T W, Barrowcliffe, D P, Thomas
openaire   +2 more sources