Results 111 to 120 of about 189,595 (350)

Red Blood Cell‐Derived Exosomal miR‐93‐5p Promotes Lung Cancer Progression through PTEN Suppression

Advanced Science, EarlyView.
Red blood cell (RBC)‐derived exosomal miR‐93‐5p is elevated in lung cancer patients and correlates with poor outcomes. Exosomal miR‐93‐5p suppresses PTEN in cancer cells, enhancing proliferation, migration, and invasion. In mouse models, therapeutic inhibition with ASO‐miR‐93 5p reduces tumor growth, highlighting a bidirectional tumor‐RBC‐tumor axis ...
Ning Li, Pushpa Dhilipkannah, Van K Holden, Ashutosh Sachdeva, Feng Jiang   +4 more
wiley   +1 more source

Use of Different Tissue Thromboplastins in the Control of Anticoagulant Therapy [PDF]

, 1957
Marc Verstraete, Patricia A. Clark, Irving S. Wright   +2 more
openalex   +1 more source

Bimetal‐Phenolic Framework to Combat Bacterial Infections via Synergistic Biofilm Dispersal, Bacterial Killing and Immune Modulation

Advanced Science, EarlyView.
A bimetal‐phenolic framework (Que‐Fe‐CeMPF) is developed by direct self‐assembly through the coordination of Fe3+ and Ce4+ with quercetin. Que‐Fe‐CeMPF exhibits multimodal activity, including cleaving matrix eDNA within biofilm, generating hydroxyl radicals via catalytic H2O2 to kill bacteria, and alleviating inflammation by stimulating macrophage ...
Yaran Wang, Fan Wu, Lei Hua, Chang Gao, Siran Wang, Yong Liu, Yijin Ren, Linqi Shi, Henny C. van der Mei, Yuanfeng Li   +9 more
wiley   +1 more source

Prolonged Anticoagulant Therapy with Heparin [PDF]

, 1952
A. Wynn, J. F. Goodwin, A. Birbeck
openalex   +1 more source

Syncope in Elderly People: A Threatening Presentation of Pulmonary Embolism: A Case Report [PDF]

, 2015
age. Its prognosis is largely unpredictable, pending the origin of the sudden loss of consciousness. We report a case of an old woman affected by severe chronic heart failure, who died soon after the development of an episode of syncope, which was ...
Bilora, Franca, Lucia, Sarolo, Pomerri, Fabio, Prandoni, Paolo   +3 more
core  

Enhancing Anti‐Tumor Effects of Engineered Extracellular Vesicles via Endocytosis Route Switching and Interferon Response Suppression

Advanced Science, EarlyView.
CD19‐293‐EV can switch the CD19 endocytosis pathway from clathrin‐mediated endocytosis to aggregation‐dependent endocytosis, leading to lysosomal degradation of the CD19/EVs complex. Degradation of the EVs leads to impairment in the IFN response and enhancement in EV uptake by target cells, creating a potent feedback cycle.
Zixuan Huang, Chaoqun Lu, Yixin Wang, Huajian Xian, Yuling Zheng, Ting Kang, Rufang Xiang, Shufeng Xie, Minghui Wang, Zeyi Li, Xiaoli Xia, Yaoyifu Yu, Wenjie Zhang, Huijian Zheng, Renyao Pan, Dan Li, Chunjun Zhao, Han Liu   +17 more
wiley   +1 more source

Anticoagulant versus antiplatelet treatment for secondary stroke prevention in patients with active cancer

Frontiers in Neurology
BackgroundApproximately 5–10% of patients with acute ischemic stroke (AIS) have known active cancer. These patients are at high risk for both recurrent AIS and major bleeding.
Moritz C. Kielkopf, Jayan Göcmen, Selina B. Venzin, Fabienne Steinauer, Mattia Branca, Anna Boronylo, Martina B. Göldlin, Johannes Kaesmacher, Adnan Mujanovic, Gianluca Costamagna, Gianluca Costamagna, Thomas R. Meinel, David J. Seiffge, Philipp Bücke, Mirjam R. Heldner, Ava L. Liberman, Hooman Kamel, Urs Fischer, Marcel Arnold, Thomas Pabst, Martin D. Berger, Simon Jung, Adrian Scutelnic, Babak B. Navi, Morin Beyeler, Morin Beyeler, Morin Beyeler   +26 more
doaj   +1 more source

Post-Thrombotic Sequelae Preventable with Anticoagulant Therapy [PDF]

, 1959
H Zilliacus
openalex   +1 more source

Design and implementation of a federated health record server [PDF]

, 2001
This paper describes the practical implementation of a federated health record serverbased on a generic and comprehensive public domain architecture and deployed in alive clinical setting.The authors, working at the Centre for Health Informatics and ...
Austin, A, Ingram, D, Kalra, D, Lloyd, D, O'Connor, A, Patterson, D   +5 more
core  

Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives

Advanced Science, EarlyView.
Micro/nanorobots (MNRs) offer a transformative approach for precision therapy in brain disorders. By overcoming biological barriers and enabling controlled propulsion, targeted delivery, and real‐time imaging/tracking, MNRs pave the way toward effective, minimally invasive treatments. This review outlines the interplay between brain disease challenges,
Qi Zhang, Dong Sun
wiley   +1 more source