Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, EarlyView.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
On improving the safety of new direct acting oral anticoagulants
Безопасность и риск фармакотерапии, 2018 One of the main causes of death and disability in the world are the thrombotic complications. Using of anticoagulants is the effective method of preventing of these life-threatening conditions.
N. Yu. Velts +6 more
doaj
Benefit-risk profile of cytoreductive drugs along with antiplatelet and antithrombotic therapy after transient ischemic attack or ischemic stroke in myeloproliferative neoplasms [PDF]
, 2018 We analyzed 597 patients with myeloproliferative neoplasms (MPN) who presented transient ischemic attacks (TIA, n = 270) or ischemic stroke (IS, n = 327). Treatment included aspirin, oral anticoagulants, and cytoreductive drugs.
Arellano-Rodrigo, Eduardo +41 more
core +5 more sources
Smart Catheters for Diagnosis, Monitoring, and Therapy
Advanced Healthcare Materials, EarlyView.This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman +12 more
wiley +1 more source
Anticoagulant therapy for ischemic stroke: A review of literature
Journal of Research in Medical Sciences, 2012 For many years, anticoagulants have been used in the emergent treatment of patients with acute ischemic stroke. Anticoagulants are prescribed in an effort to prevent first or recurrent stroke, especially among patients with cardioembolism due to arterial
Mohammad Mehdi Shahpouri +4 more
doaj
Short runs of atrial arrhythmia and stroke risk: a European-wide online survey among stroke physicians and cardiologists [PDF]
, 2016 Methods: An online survey of cardiologists and stroke physicians was carried out to assess current management of patients with short runs of atrial arrhythmia within Europe. Results: Respondents included 311 clinicians from 32 countries.
Abdul-Rahim, A.H. +5 more
core +1 more source
Microfluidic Simulation and Optimization of Blood Coagulation Factors and Anticoagulants in Polymethyl Methacrylate Microchannels [PDF]
, 2021 Philip Nathaniel Immanuel +2 more
openalex +1 more source
Magnetic Milli‐Spinner for Robotic Endovascular Surgery
Advanced Materials, EarlyView.The magnetic milli‐spinner, with its unique structural design, achieves rapid and stable navigation through complex vasculature at speeds up to 23 cm·s−1. It further enables multifunctional treatment, including localized suction and shear for efficient clot removal, targeted drug delivery, and in situ embolization for aneurysm therapy, establishing it ...
Shuai Wu +7 more
wiley +1 more source
International Digestive Endoscopy Network consensus on the management of antithrombotic agents in patients undergoing gastrointestinal endoscopy [PDF]
Clinical EndoscopyAntithrombotic agents, including antiplatelet agents and anticoagulants, are widely used in Korea because of the increasing incidence of cardiocerebrovascular disease and the aging population. The management of patients using antithrombotic agents during
Seung Joo Kang +16 more
doaj +1 more source
Shear viscosity and nonlinear behaviour of whole blood under large amplitude oscillatory shear [PDF]
, 2013 We investigated experimentally the rheological behavior of whole human blood subjected to large amplitude oscillatory shear under strain control to assess its nonlinear viscoelastic response.
Alves, M.A. +6 more
core +1 more source