Results 91 to 100 of about 269,235 (359)

Surface Engineering of Thrombus‐Targeting Nanocarriers for Cardiovascular Diseases: A Short Review

Advanced Materials Interfaces, EarlyView.
This paper systematically introduces surface modification strategies for thrombus‐targeting nanocarriers, highlights the clinical significance of nanocarrier‐based thrombolysis therapies, and prospects the synergy of combing thrombolysis and anti‐inflammatory therapies for enhanced therapeutic effect.
Xinyue Ge, Lei Ding, Wenjun Zhao, Bohan Cui, Xiang Guan, Mingfei Pan, Qingguo Li, Ning Gu   +7 more
wiley   +1 more source

Perioperative management of patients on direct oral anticoagulants

Thrombosis Journal, 2017
Direct oral anticoagulants (DOACs) have been licensed worldwide for several years for various indications. Each year, 10–15% of patients on oral anticoagulants will undergo an invasive procedure and expert groups have issued several guidelines on ...
Virginie Dubois, A. Dincq, J. Douxfils, B. Ickx, C. Samama, J. Dogné, M. Gourdin, B. Châtelain, F. Mullier, S. Lessire   +9 more
semanticscholar   +1 more source

A Wireless Soft Optical Blood Sensor for Colonoscopy

Advanced Sensor Research, EarlyView.
This works presents an “add‐on” wireless soft optical blood sensor for the traditional colonoscopy. It can reliably detect bleeding behind the colonoscope's distal tip camera via optical absorption, without optical fibers, and wirelessly transmit data to the processor.
Kamin Palkawong‐Na‐Ayuddhaya, Arincheyan Gerald, Addison Chu, Johann Pang, Arnav Mankad, Hiroyuki Aihara, Sheila Russo   +6 more
wiley   +1 more source

Direct Oral Anticoagulants: A Quick Guide.

European Cardiology, 2017
Vitamin K antagonists, such as warfarin, have been the anticoagulants of choice for many years for patients with AF and other thrombotic conditions. The introduction of direct oral anticoagulants (DOACs) as alternatives represents a major advance in ...
Sikorska Julia, Uprichard James
semanticscholar   +1 more source

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

Advanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu, Guoqing Jing, Shujuan Wu, Min Yuan, Yingyue Dong, Xue Chen, Huimin Zhou, Hailong Gong, Jing Zuo, Xiaojing Wu, Xuemin Song   +10 more
wiley   +1 more source

New classification‐oriented treatment strategy for portal vein thrombosis after hepatectomy

Annals of Gastroenterological Surgery, 2020
Aim This study sought to evaluate the incidence, risk factors, and clinical outcomes of portal vein thrombosis after hepatectomy. Furthermore, we proposed a novel classification and treatment strategy for portal vein thrombosis after hepatectomy. Methods
Shinji Onda, Kenei Furukawa, Yoshihiro Shirai, Ryoga Hamura, Takashi Horiuchi, Jungo Yasuda, Hironori Shiozaki, Takeshi Gocho, Hioaki Shiba, Toru Ikegami   +9 more
doaj   +1 more source

Management of thrombosis in children and neonates: practical use of anticoagulants in children.

Hematology. American Society of Hematology. Education Program, 2018
Venous thrombosis (VTE) in children and neonates presents numerous management challenges. Although increasing in frequency, VTE in children and neonates is still uncommon compared with adults.
P. Monagle, F. Newall
semanticscholar   +1 more source

Optogenetic‐Controlled iPSC‐Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice

Advanced Science, EarlyView.
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao, Lingxue Niu, Zhihao Wang, Di Dai, Shasha Tang, Xiaoding Ma, Zhenqiang Deng, Guiling Yu, Yang Zhou, Tao Yan, Xingwan Liu, Deqiang Kong, Linfeng Hu, Xiang Li, Junwei Zhao, Fengfeng Cai, Meiyan Wang, Haifeng Ye   +17 more
wiley   +1 more source

Pharmacology of anticoagulants used in the treatment of venous thromboembolism

Journal of Thrombosis and Thrombolysis, 2016
Anticoagulant drugs are the foundation of therapy for patients with VTE. While effective therapeutic agents, anticoagulants can also result in hemorrhage and other side effects.
E. Nutescu, Allison E. Burnett, J. Fanikos, S. Spinler, A. Wittkowsky   +4 more
semanticscholar   +1 more source

Maximizing Efficacy of Cancer Nanovaccines and Immune Cells Landscape in Responders and Non‐Responders to Immunotherapy

Advanced Science, EarlyView.
To maximize the efficacy of cancer vaccines, adjuvants, collection, lysis, purification, oxidation, loading sites, and sizes, etc., are investigated. The optimized cancer nanovaccines loading whole tumor antigens can cure all or most tumor‐bearing mice in multiple mouse cancer models.
Xiangxiang Xu, Lu Diao, Jin Wang, Ao Zhu, Xianlan Chen, Yan Zheng, Yuhan Liu, Kang Hu, Jiashan Zhu, Cheng Ding, Chang Li, Yunzhi Pan, Jun Zhao, Mi Liu   +13 more
wiley   +1 more source