Results 81 to 90 of about 143,207 (265)

A Hydrogen Sulfide–Releasing Dynamic Hydrogel Modulates Coordinated Neurovascular, Immune, and Angiogenic Responses for Scar‐Suppressed Diabetic Wound Repair

open access: yesAdvanced Science, EarlyView.
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning   +7 more
wiley   +1 more source

Novel pharmacological approaches of anticoagulant therapy

open access: yes, 2014
Warfarin and heparin are the traditional anticoagulants used for over 60 years. Their most common applications are for the prevention of thromboembolic diseases that may arise from atrial fibrillation and deep vein thrombosis which may cause stroke and ...
Straker, Sina
core  

Novel oral anticoagulants.

open access: yes, 2009
Summary Oral anticoagulants have been used widely for the treatment of venous thromboembolism and stroke prevention. The vitamin K antagonists (VKAs), such as warfarin, have been around for the last 65 years and its efficacy as thromboprophylaxis ...
Khoo, Chee-Wah   +7 more
core   +1 more source

Selected attributes of oral anticoagulants.

open access: yes, 2021
Selected attributes of oral anticoagulants.
Yang Hu (315392)   +11 more
core   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

open access: yesAdvanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang   +10 more
wiley   +1 more source

Anticoagulants and extracorporeal circuits

open access: yes, 1997
Anticoagulants are pivotal to achieve circulation in extracorporeal circuits. In this review we discuss several anticoagulants in clinical use or in the preclinical phase.
Nurmohamed, M T   +3 more
core   +1 more source

Influence of anticoagulants on determination of H2O2 levels in blood: Comparison of citrate and EDTA [PDF]

open access: yes, 2018
Background H2O2 is supposed to be part of the laboratory test panel for assessment of oxidative stress. This molecule contributes to oxidative stress by reacting with Fe2+ ions to produce hydroxyl radicals.
Bwititi, P., Chalada, MJ, Nwose, EU
core   +1 more source

Biomimetic Nanoplatform for Dual Target Nano‐Metabolic Therapy in Diabetes‐Associated Biofilm Infections

open access: yesAdvanced Science, EarlyView.
A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li   +13 more
wiley   +1 more source

Spontaneous suprachoroidal hemorrhage due to the excessive anticoagulation therapy. Case report

open access: yesOftalʹmologiâ, 2014
Anticoagulant therapy is often used to treat various conditions. This often can deviate in the hemostatic system in the direction of hypocoagulation and increase risk of hemostatic complications. The article describes suprachoroidal hemorrhage in the eye
A. Stepanov,   +4 more
doaj   +1 more source

Intracranial haemorrhage in patients with atrial fibrillation on anticoagulants

open access: yes, 2018
Anticoagulants increase the risk of bleeding. Rarely, they become devastating instead of preventing thrombosis and embolism. Intracranial haemorrhagic complications in particular can be disabling or fatal.
Arnold, Marcel   +5 more
core   +1 more source

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