Advanced Science, EarlyView.After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin +6 more
wiley +1 more source
Blood collection technique, anticoagulants and storing temperature have minor effects on the isolation of polymorphonuclear neutrophils [PDF]
, 2020 Julia Krabbe +7 more
openalex +1 more source
Cancer and thrombosis: Managing the risks and approaches to thromboprophylaxis [PDF]
, 2006 Patients with cancer are at increased risk of venous thromboembolism (VTE) compared with patients without cancer. This results from both the prothrombotic effects of the cancer itself and iatrogenic factors, such as chemotherapy, radiotherapy, indwelling
Altinbas M +36 more
core +1 more source
Advanced Science, EarlyView.This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao +5 more
wiley +1 more source
Role of Physical Therapists in the Management of Individuals at Risk for or Diagnosed With Venous Thromboembolism: Evidence-Based Clinical Practice Guideline [PDF]
, 2016 The American Physical Therapy Association (APTA), in conjunction with the Cardiovascular & Pulmonary and Acute Care sections of APTA, have developed this clinical practice guideline to assist physical therapists in their decision-making process when ...
Auten, Beth +5 more
core +1 more source
Global Thrombosis Test - a possible monitoring system for the effects and safety of dabigatran [PDF]
, 2015 © Otsui et al. 2015BACKGROUND: Dabigatran is an alternative to warfarin (WF) for the thromboprophylaxis of stroke in patients with non-valvular atrial fibrillation (NVAF). The advantage of dabigatran over WF is that monitoring is not required; however, a
Gorog, Diana A +8 more
core +2 more sources
Advanced Science, EarlyView.In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou +13 more
wiley +1 more source
Spontaneous suprachoroidal hemorrhage due to the excessive anticoagulation therapy. Case report
Oftalʹmologiâ, 2014 Anticoagulant therapy is often used to treat various conditions. This often can deviate in the hemostatic system in the direction of hypocoagulation and increase risk of hemostatic complications. The article describes suprachoroidal hemorrhage in the eye
A. Stepanov, +4 more
doaj +1 more source
Balancing ischemic and hemorrhagic risk after ICH - Re-starting antiplatelets and anticoagulants? [PDF]
, 2023 Rustam Al‐Shahi Salman
openalex +1 more source
Dipyridamole plus aspirin versus aspirin alone in the secondary prevention after TIA or stroke: a meta-analysis by risk [PDF]
, 2008 Objectives: Our aim was to study the effect of combination therapy with aspirin and dipyridamole (A+D) over aspirin alone (ASA) in secondary prevention after transient ischemic attack or minor stroke of presumed arterial origin and to perform subgroup ...
A Algra +6 more
core +2 more sources