Results 11 to 20 of about 227,135 (339)
Background Anticoagulants are the cornerstone therapy for the management of venous thromboembolism (VTE) and atrial fibrillation (AF). Pharmacists should be confident and equipped with the skill and updated knowledge in managing anticoagulation therapy ...
Sze Ling Tan +4 more
doaj +1 more source
Outcomes Associated With Oral Anticoagulants Plus Antiplatelets in Patients With Newly Diagnosed Atrial Fibrillation. [PDF]
Importance: Patients with nonvalvular atrial fibrillation at risk of stroke should receive oral anticoagulants (OAC). However, approximately 1 in 8 patients in the Global Anticoagulant Registry in the Field (GARFIELD-AF) registry are treated with ...
Bassand, J-P +17 more
core +2 more sources
Brainstem stroke in a Nigerian male with prosthetic heart valves—A case report
Stroke following cardiac surgery particularly valvular implantation is an anticipated complication. This is due to the prosthetic valve as well as possible associated comorbid conditions. There is dearth of published data on stroke post valve replacement
Ralph C Anakwue +3 more
doaj +1 more source
How we treat bleeding associated with direct oral anticoagulants [PDF]
Direct oral anticoagulants are at least as effective as vitamin K antagonists for the prevention and treatment of thromboembolism. Unfortunately, differently from vitamin K antagonists, they have the great drawback of lacking specific antidotes in the ...
Franchini, Massimo +4 more
core +1 more source
Patient safety and estimation of renal function in patients prescribed new oral anticoagulants for stroke prevention in atrial fibrillation [PDF]
OBJECTIVE: In clinical trials of dabigatran and rivaroxaban for stroke prevention in atrial fibrillation (AF), drug eligibility and dosing were determined using the Cockcroft-Gault equation to estimate creatine clearance as a measure of renal function ...
Ashman, N +6 more
core +2 more sources
Background Risks of antithrombotic switching is not investigated in elderly atrial fibrillation patients. Objectives To investigate the effectiveness and safety of antithrombotic treatment and switching of antithrombotic treatment in elderly patients ...
Hanne Ehrlinder +4 more
doaj +1 more source
Anticoagulants for acute ischaemic stroke [PDF]
Peer reviewedPublisher ...
Counsell, Carl +2 more
core +1 more source
Introduction The activated partial thromboplastin time (aPTT) and the prothrombin time (PT) are widely available coagulation parameters which are however poor predictors of the anticoagulant effect of direct oral anticoagulants (DOACs).
Jonathan Evrard +8 more
doaj +1 more source
Improving treatment for acute ischemic stroke—Clot busting innovation in the pipeline
Acute ischemic stroke is a consequence of disrupted blood flow to the brain, caused by thrombosis—the pathological formation of occlusive clots within blood vessels, which can embolize distally to downstream tissues and microvasculature.
Joanna Shu Ting Liu +6 more
doaj +1 more source
Abstract The processes that underly the clotting of blood are still far from adequately understood, in spite of the many facts uncovered by generations of patient investigators. The classical scheme associated with the name of Morawitz1, although neither complete nor universally accepted, is still useful as a summary of the main events ...
openaire +2 more sources

