Benefit-risk profile of cytoreductive drugs along with antiplatelet and antithrombotic therapy after transient ischemic attack or ischemic stroke in myeloproliferative neoplasms [PDF]
We analyzed 597 patients with myeloproliferative neoplasms (MPN) who presented transient ischemic attacks (TIA, n = 270) or ischemic stroke (IS, n = 327). Treatment included aspirin, oral anticoagulants, and cytoreductive drugs.
Arellano-Rodrigo, Eduardo+41 more
core +5 more sources
Engineering Highly Cellularized Living Materials via Mechanical Agitation
A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani+9 more
wiley +1 more source
On improving the safety of new direct acting oral anticoagulants
One of the main causes of death and disability in the world are the thrombotic complications. Using of anticoagulants is the effective method of preventing of these life-threatening conditions.
N. Yu. Velts+6 more
doaj
High frequency of inadequate test requests for antiphospholipid antibodies in daily clinical practice [PDF]
Background: We have empirically noted that many physicians routinely request anti-phospholipid antibodies (aPL) without a correct clinical indication. The aim of this study was to evaluate retrospectively whether aPL testing at our Thrombosis Centre was ...
Barcellona D+3 more
core +1 more source
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren+13 more
wiley +1 more source
Anticoagulant therapy for ischemic stroke: A review of literature
For many years, anticoagulants have been used in the emergent treatment of patients with acute ischemic stroke. Anticoagulants are prescribed in an effort to prevent first or recurrent stroke, especially among patients with cardioembolism due to arterial
Mohammad Mehdi Shahpouri+4 more
doaj
Large-scale structure of brown rat (Rattus norvegicus) populations in England: effects on rodenticide resistance [PDF]
The brown rat (Rattus norvegicus) is a relatively recent (
Adams, Sally+6 more
core +2 more sources
Tannic acid‐selenocystamine (TA‐SeCA) nanocoating enables stable, sustained catalytic nitric oxide (NO) release on catheter surfaces. This one‐step phenol‐amine coating improves catheter functionality by enhancing endogenous NO production, supporting vascular function, and reducing inflammation.
Qingqing Fan+7 more
wiley +1 more source
BackgroundDespite higher thromboembolism risk, women with atrial fibrillation have lower oral anticoagulation (OAC) use compared to men. The influence of the CHA2DS2‐VASc score or the introduction of non–vitamin K OACs on this relationship is not known ...
Lauren E. Thompson+11 more
doaj +1 more source
Rivaroxaban for venous thromboembolism prophylaxis in abdominoplasty after massive weight loss: 396 cases [PDF]
Introduction: Abdominoplasty is one of the most popular aesthetic procedures performed in Brazil. Postbariatric patients present a challenge to the plastic surgeon as not only do they have complex reconstructive challenges but also they have residual ...
Guilherme Berto Roça+2 more
doaj +1 more source