Results 221 to 230 of about 158,411 (308)

Identification of Coagulation Phenotypes Using Viscoelastic and Conventional Assays During Veno‐Venous Extracorporeal Membrane Oxygenation: A Hierarchical Clustering Analysis

open access: yesArtificial Organs, EarlyView.
Hierarchical clustering of viscoelastic and conventional coagulation parameters identified three distinct phenotypes in V‐V ECMO patients, revealing substantial APTT–CK‐R discordance and highlighting the value of TEG‐derived markers for detecting coagulopathy not captured by standard monitoring.
Daisuke Irimada   +9 more
wiley   +1 more source

Anticoagulation Strategies in Adults Undergoing Extracorporeal Membrane Oxygenation: A Systematic Review and Meta‐Analysis

open access: yesArtificial Organs, EarlyView.
In this meta‐analysis of 2 775 adult ECMO patients from non‐randomized studies, direct thrombin inhibitors and low‐molecular‐weight heparins demonstrated a favorable efficacy and safety profile over unfractionated heparin. These findings suggest them to be effective alternatives to unfractionated heparin, underscoring the urgent need for randomized ...
Vincenz Scharner   +7 more
wiley   +1 more source

The impact of systemic long‐term medications for the development of age‐related macular degeneration

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of central vision loss in the elderly; however, the systemic factors that modulate its incidence and progression remain unclear. We sought to determine whether long‐term use of systemic medications, including diabetes and antithrombotic medications, corticosteroids and ...
Hanna Heloterä   +3 more
wiley   +1 more source

Cardiotoxicity of BRAF/MEK inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe   +4 more
wiley   +1 more source

Anticoagulation therapy and related outcomes among Asian patients after bioprosthetic valve replacement. [PDF]

open access: yesBMC Cardiovasc Disord
Liu TY   +9 more
europepmc   +1 more source

Agrimoniin Alleviates Ferroptosis in Cold‐Stored DCD Liver Grafts Through Activation of the Nrf‐2 Pathway

open access: yesCell Proliferation, EarlyView.
Supplementing the liver preservation solution with agrimoniin protects donation after cardiac death (DCD) grafts by activating the Nrf‐2 pathway. This reduces ferroptosis, oxidative stress, and inflammation during cold storage, significantly improving graft viability.
Enqiang Chang   +5 more
wiley   +1 more source

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