Results 181 to 190 of about 72,257 (246)

High-dose Vitamin D may Have No Effect on Mortality in Vitamin D-deficient Pediatric ICU Patients because the Study Design is Inappropriate. [PDF]

Indian J Crit Care Med
Scorza FA, Scorza CA, Finsterer J.
europepmc   +1 more source

Toxicological analyses of the bone matrix: Successes and challenges

Archaeometry, EarlyView.
Abstract This study aimed to conduct an in‐depth and systematic literature review dealing with toxicological analyses on human bone tissue and focusing on the forensic toxicological and archaeotoxicological field. Several studies have focused their research on medical drugs, drugs of abuse, and trace elements on both human cadavers and skeletal remains,
Gaia Giordano, Lucie Biehler‐Gomez, Cristina Cattaneo, Domenico Di Candia   +3 more
wiley   +1 more source

The Oxidative Stress in Epilepsy-Focus on Melatonin. [PDF]

Int J Mol Sci
Kamieniak M, Kośmider K, Miziak B, Czuczwar SJ.   +3 more
europepmc   +1 more source

Recommended approaches for integration of population pharmacokinetic modelling with precision dosing in clinical practice

British Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 1064-1079, April 2025.
Current methods of dose determination have contributed to suboptimal and inequitable health outcomes in underrepresented patient populations. The persistent demand to individualise patient treatment, alongside increasing technological feasibility, is leading to a growing adoption of model‐informed precision dosing (MIPD) at point of care.
Monika Berezowska, Isaac S. Hayden, Andrew M. Brandon, Arsenii Zats, Mehzabin Patel, Shelby Barnett, Kayode Ogungbenro, Gareth J. Veal, Alaric Taylor, Jugal Suthar   +9 more
wiley   +1 more source

Multimodal Machine Learning Prediction of 12‐Month Suicide Attempts in Bipolar Disorder

Bipolar Disorders, EarlyView.
ABSTRACT Introduction Bipolar disorder (BD) patients present an increased risk of suicide attempts. Most current machine learning (ML) studies predicting suicide attempts are cross‐sectional, do not employ time‐dependent variables, and do not assess more than one modality.
Alessandro Pigoni, Isidora Tesic, Cecilia Pini, Paolo Enrico, Lorena Di Consoli, Francesca Siri, Guido Nosari, Adele Ferro, Letizia Squarcina, Giuseppe Delvecchio, Paolo Brambilla   +10 more
wiley   +1 more source

In Vitro Antioxidant Activity and Anticonvulsant Properties on Zebrafish PTZ-Induced Seizure Model of a Tilia viridis Aqueous Extract. [PDF]

J Pharmacopuncture
Martin EMS, Sosa AM, Martinez CS, Prieto J, Marrassini C, Dobrecky CB, Alonso MR, Anesini C.   +7 more
europepmc   +1 more source

Impact of Activation Therapy for Inpatients With Major Depression: Primary and Secondary Outcomes From a Randomised Controlled Trial

Bipolar Disorders, EarlyView.
ABSTRACT Introduction Inpatient depression is associated with high morbidity and significant cognitive impairment. Inpatient treatment often focuses on short‐term stabilization with medication. Readmission rates are high. We examined the impact of a novel psychological intervention, activation therapy (AT, Behavioural Activation combined with Cognitive
Katie M. Douglas, Zoe A. Odering, Jennifer Jordan, Marie T. Crowe, Cameron J. Lacey, Christopher M. Frampton, Ian R. E. Averill, Cecilia Smith Hamel, Christopher R. Bowie, Richard J. Porter   +9 more
wiley   +1 more source

Sinapinic acid as a potential therapeutic agent for epilepsy through targeting NMDA receptors and nitrite level. [PDF]

Sci Rep
Ghasemi M, Amini-Khoei H, Bijad E, Rafieian-Kopaei M, Sureda A, Lorigooini Z.   +5 more
europepmc   +1 more source

Twenty-four years of prescription patterns in bipolar disorder inpatients with vs without lithium: a pharmacoepidemiological analysis of 8,707 cases in German-speaking countries. [PDF]

Int J Bipolar Disord
Greil W, de Bardeci M, Nievergelt N, Erfurth A, Hasler G, Bridler R, Toto S, Grohmann R, Seifert J, Schoretsanitis G.   +9 more
europepmc   +1 more source

Patient experiences of behavioural therapy for bipolar depression: A qualitative study

British Journal of Clinical Psychology, EarlyView.
Abstract Background Although multiple qualitative studies have explored participants' experiences of behavioural activation (BA) for unipolar depression, none have investigated the experiences of BA in people with bipolar depression. This is of particular interest because qualitative studies concerning the experience of receiving therapy can help ...
Sakir Yilmaz, Anna Hancox, Molly Price, Jemma Regan, Barney Dunn, Heather O'Mahen, Kim Wright   +6 more
wiley   +1 more source