Abstract Background Hypoxia modulates inflammation and oxidative stress through hypoxia‐inducible factor‐1α (HIF‐1α). Ferroptosis, an iron‐dependent cell death process, is regulated by glutathione peroxidase‐4 (GPX4) and involves lipid peroxidation markers like malondialdehyde (MDA).
Büşra Yılmaz +5 more
wiley +1 more source
Anticonvulsant Potential of the Essential Oil of <i>Croton Heliotropiifolius</i> Kunth: In Vivo and In Silico Approach. [PDF]
da Cunha MES +8 more
europepmc +1 more source
Peptic ulcer disease: Insights and risk factors
Abstract Objectives Peptic ulcer disease (PUD), affects adults and children, with Helicobacter pylori (H. pylori) infection being the most frequent cause. Diagnosis requires an upper gastrointestinal endoscopy (UGE) and invasive tests. However, besides H. pylori, risk factors for PUD in children remain unclear.
Haidar Houmani +6 more
wiley +1 more source
Epilepsy Therapy Screening From 1975 to 2026 and Beyond: Merging Established and New Approaches to Develop Novel Therapies. [PDF]
Metcalf CS +3 more
europepmc +1 more source
Abstract Hepatitis C virus (HCV) remains a significant global health burden, with vertical transmission being the primary route of infection in children. Direct‐acting antivirals (DAAs) have transformed HCV treatment in pediatrics, but limited data exist on their administration in medically complex children who are dependent on enteral tubes. We report
Connie Chen, Leah Gibson, James Squires
wiley +1 more source
Serotonin Associated Mechanisms in Sudden Unexpected Death in Epilepsy: A Review. [PDF]
Li B +6 more
europepmc +1 more source
Excretion of organic acids associated with biotin deficiency in chronic anticonvulsant therapy [PDF]
Berlit, Peter +3 more
core
Hidradenitis suppurativa (HS) is often diagnosed late, complicating management. In this nationwide Danish study including 10,196 patients with dermatologist‐verified HS, we examined treatment patterns before and after referral to specialised hospital care.
Nana A. L. Rosenø +8 more
wiley +1 more source
Anticonvulsant Use in Older Age Bipolar Disorder in a Global Sample from the Global Aging and Geriatric Experiments in Bipolar Disorder Project: Utilisation d'anticonvulsivants pour le traitement des troubles bipolaires du sujet âgé auprès d'un échantillon mondial provenant du projet GAGE-BD. [PDF]
Bodenstein KC +36 more
europepmc +1 more source
ABSTRACT This study aimed to compare efficacy and safety of ultrasound‐guided erector spinae plane block (ESPB) using liposomal (LB) versus conventional bupivacaine (CB), each plus standardized gabapentin, in patients with postherpetic neuralgia (PHN). A total of 116 PHN patients were randomized to ESPB‐LB or ESPB‐CB; both groups received standardized ...
Xia‐Jing Xu +3 more
wiley +1 more source

