Transcriptional signatures of cortical morphometric variability in temporal lobe epilepsy
Abstract Objective Widespread cognitive deficits in temporal lobe epilepsy (TLE) are associated with macroscale brain structural changes. However, the correlation between the changes in the cortical morphological similarity of the TLE and gene expression remains unclear.
Yaping Dong +5 more
wiley +1 more source
<i>Caenorhabditis</i> Intervention Testing Program: the anticonvulsant levetiracetam does not extend lifespan in nematodes. [PDF]
Akella JS +11 more
europepmc +1 more source
Cumulative electroconvulsive therapy sessions and focal epilepsy: A nationwide cohort study in Japan
Abstract Objective Electroconvulsive therapy (ECT) is widely used for severe psychiatric disorders, yet concerns remain regarding possible epileptogenic effects associated with prolonged or repeated exposure. We examined the association between cumulative ECT sessions and focal epilepsy in a nationwide Japanese cohort.
Masahiro Hata +4 more
wiley +1 more source
"Adverse event reports of seizure for insomnia medication from 1967 to 2023". The challenge of using hypnotic medication in people with epilepsy. [PDF]
Di Mauro G, Liguori C.
europepmc +1 more source
Abstract Objective Epilepsy affects approximately 50 million people worldwide and, although primarily attributed to neuronal dysfunction, increasing evidence highlights a critical role of glial cells, particularly astrocytes, in the pathophysiological mechanisms.
Chiara Lötzsch +5 more
wiley +1 more source
Lithium prescription patterns for bipolar disorder at a psychiatric hospital in KwaZulu-Natal. [PDF]
Motebele NN +3 more
europepmc +1 more source
Recent Advancement in Synthesis of Isatin as Anticonvulsant Agents: A Review
G. Mathur, S. Nain
semanticscholar +1 more source
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar +4 more
wiley +1 more source
GABAergic Modulation and Neurobehavioral Effects of Arjunolic Acid, a Pentacyclic Triterpene Isolated From Combretum Mellifluum Eichler: In Vivo and Molecular Docking Evaluation. [PDF]
Freitas YJDS +11 more
europepmc +1 more source

