Developmental pathways to autism in tuberous sclerosis complex: Evidence from a longitudinal cohort
Abstract The association between autism spectrum disorder (hereafter referred to as autism) and tuberous sclerosis complex (TSC) is well established, yet the developmental pathways linking genetic mutation, cortical pathology, and epilepsy with autism remain unclear. The Tuberous Sclerosis 2000 Study recruited children newly diagnosed with TSC (N = 125)
Fiona S. McEwen +12 more
wiley +1 more source
CAQ Corner: Basic concepts of transplant immunology
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Anticonvulsant activity of aza-Biginelli derivatives related to JM-II-43A and HSAB-based rationalization of their pharmacological profile. [PDF]
Ríos-Guerra H +8 more
europepmc +1 more source
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source
From molecular design to antiepileptic evaluation: sulfonamide-pyrazole derivatives as promising neuroactive agents. [PDF]
Elgohary MK +9 more
europepmc +1 more source
Practice parameter: Anticonvulsant prophylaxis in patients with newly diagnosed brain tumors
Michael Glantz +12 more
semanticscholar +1 more source
New insights into epileptic spasm generation and treatment from the TTX animal model
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann +2 more
wiley +1 more source
Medicinal compounds with antiepileptic/anticonvulsant activities
HuiCong Zhu +6 more
semanticscholar +1 more source
Frontiers in EEG as a tool for the management of pediatric epilepsy: Past, present, and future
Abstract Electroencephalography (EEG) has evolved into an indispensable tool in pediatric epilepsy, fundamentally transforming the diagnosis, classification, and management of this condition. This review chronicles the historical journey of EEG from its groundbreaking inception to its current pivotal role in delineating distinct pediatric epilepsy ...
Hiroki Nariai
wiley +1 more source
Studies on the anticonvulsant potential of 6-gingerol, an active ingredient of ginger rhizome. [PDF]
Nieoczym D +11 more
europepmc +1 more source

