Results 111 to 120 of about 53,577 (300)
Journal of Medicinal Plants, 2005 Background: Thymoquinone, the major constituent of Nigella sativa seeds, is a biologically active compound, which possesses several pharmacological effects. Objective: The aim of the present study was to evaluate the anticonvulsant effect of thymoquinone
S Parvardeh +3 more
doaj
Substitution of anticonvulsant drugs
, 2009 Bernhard J Steinhoff1, Uwe Runge2, Otto W Witte3, Hermann Stefan4, Andreas Hufnagel5, Thomas Mayer6, Günter Krämer71Epilepsy Center, Kehl-Kork, Germany; 2Department of Neurology, University of Greifswald, Greifswald, Germany ...
Hermann Stefan +4 more
core
SYNTHESIS AND ANTICONVULSANT ACTIVITIES OF SMALL N-SUBSTITUTED 2, 5-DIMETHYL PYRROLE AND BIPYRROLE [PDF]
, 2020 A series of N-substituted 2, 5-dimethyl pyrrole and bipyrrole derivatives were synthesized by Paal-Knorr method and evaluated for anticonvulsant activity at NIH.
Reema Sinha +3 more
core
Dosing HIV integrase inhibitors with enzyme inducers: Convenience vs. control?
British Journal of Clinical Pharmacology, EarlyView.
Catia Marzolini, Saye Khoo
wiley +1 more source
Monthly or menstrual? A scoping review of catamenial epilepsy and non‐menstrual seizure rhythms
Epilepsia, EarlyView.Abstract Objective Despite the reported high prevalence of catamenial epilepsy (CE), the condition remains poorly defined, with lack of consensus on what entails a menstrual‐related seizure exacerbation. Emerging evidence of multiday cycles of seizure activity, including about‐monthly cycles, present in both men and women, further confound the ...
Victoria Wong +4 more
wiley +1 more source
Altered cortical synchronization in photosensitive idiopathic generalized epilepsy
Epilepsia, EarlyView.Abstract Objective To characterize cortical excitability and synchronization dynamics in patients with idiopathic generalized epilepsy (IGE) and photosensitivity by assessing steady‐state visual evoked potentials (SSVEPs) elicited by intermittent photic stimulation.
Alessandro Benedetto +5 more
wiley +1 more source
Recent developments on triazole nucleus in anticonvulsant compounds: a review
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 Epilepsy is one of the common diseases seriously threatening life and health of human. More than 50 million people are suffering from this condition and anticonvulsant agents are the main treatment.
Ming-Xia Song, Xian-Qing Deng
doaj +1 more source
Регуляторные исследования и экспертиза лекарственных средств, 2018 Optimization of pharmacotherapy (selection of optimal doses and dosing intervals) is a major objective of clinical pharmacology. This objective may be achieved, in part, by implementation of modern pharmacokinetic approaches and the use of therapeutic ...
V. V. Arkhipov +4 more
doaj
Statin use and risk of remote seizure after first new onset status epilepticus
Epilepsia, EarlyView.Abstract Objective Preclinical evidence supports the role of statins as antiepileptogenic agents. In this study, we investigated the risk of remote unprovoked seizures (RS) according to the use of statin therapy in a cohort of first‐ever status epilepticus (SE) survivors. Methods Retrospective analysis was made of adult patients (age ≥ 14 years) with a
Niccolò Orlandi +12 more
wiley +1 more source