Results 101 to 110 of about 3,750,719 (375)

Effects of arachidonyl-2'-chloroethylamide (ACEA) on the protective action of various antiepileptic drugs in the 6-Hz corneal stimulation model in mice.

open access: yesPLoS ONE, 2017
Accumulating evidence indicates that cannabinoid CB1 receptor ligands play a pivotal role in seizures, not only in preclinical studies on animals, but also in clinical settings.
Jarogniew J Luszczki   +8 more
doaj   +1 more source

Headaches [PDF]

open access: yes, 2006
A 30 year old lady was seen by her family doctor during a busy clinic complaining of three episodes of left-sided headache over the previous four months.
Camilleri, Myriam
core   +1 more source

Antiprotozoal Activity of Highly Substituted Pyrazole and Pyrimidine Derivatives

open access: yesChemMedChem, EarlyView.
Based on previously identified antimalarial agents, a series of highly substituted pyrazole and pyrimidines derivatives has been synthesized and tested for antiplasmodial and antileishmanial activity. Selected derivatives show promising antiplasmodial effect with a predicted favorable pharmacokinetic profile.
Matteo Lusardi   +7 more
wiley   +1 more source

Brain pathology caused in the neonatal macaque by short and prolonged exposures to anticonvulsant drugs. [PDF]

open access: yesNeurobiol Dis, 2021
Noguchi KK   +12 more
europepmc   +1 more source

Drug-drug interactions in repeat prescriptions at village dispensaries (bereg) in Malta [PDF]

open access: yes, 2013
Inappropriate treatments and drug-drug interactions (DDIs) are known to occur in settings where repeat prescriptions are issued. In view of this, a study was carried out to document any such problematic drug prescribing and propose changes that would
Bugeja, Anton
core  

Antiepileptic drugs’ tolerability and safety – a systematic review and meta-analysis of adverse effects in dogs [PDF]

open access: yes, 2016
Various anti-epileptic drugs (AEDs) are used for the management of idiopathic epilepsy (IE) in dogs. Their safety profile is an important consideration for regulatory bodies, owners and prescribing clinicians.
A Stabile   +105 more
core   +3 more sources

Novel 4,5‐Dihydrothiazole‐phenylpiperazine Derivatives: Synthesis, Docking Studies and Pharmacological Evaluation as Serotonergic Agents

open access: yesChemMedChem, Accepted Article.
We have described the synthesis of a new series of LCAPs (long‐chain arylpiperazine) as serotoninergic ligands (FG 1‐18). The combination of structural elements including heterocyclic nucleus, propyl chain and 4,5‐dihydrothiazol‐2‐ylphenylpiperazines, led to the preparation of different derivatives tested for their affinity toward 5‐HT1A, 5‐HT2A and 5 ...
Giorgia Andreozzi   +18 more
wiley   +1 more source

Determination of Topiramate and Carbamazepine in Plasma by Combined Dispersive Liquid–Liquid Microextraction and Gas Chromatography–Mass Spectrometry

open access: yesSeparations
Dispersive liquid–liquid microextraction, an environmentally friendly extraction technique, followed by gas chromatography–mass spectrometry operating in selected ion monitoring (SIM) mode, is here presented for the simultaneous determination of two ...
Pamela Cabarcos-Fernández   +3 more
doaj   +1 more source

Postnatal onset of severe growth retardation after in utero exposure to carbamazepine and phenobarbital: a case report

open access: yesJournal of Medical Case Reports, 2009
Introduction Anticonvulsant drugs taken by pregnant women to prevent seizures are among the most common causes of potential harm to the fetus. While the immediate harmful effects manifesting as congenital abnormalities are well known, the long-term ...
Liguori Alice, Cianfarani Stefano
doaj   +1 more source

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