Results 111 to 120 of about 3,750,719 (375)

New drugs on the Internet : the case of Camfetamine [PDF]

, 2014
Copyright © 2014 Eduardo Cinosi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Acciavatti, Tiziano, Cinosi, Eduardo, Corazza, Ornella, di Giannantonio, Massimo, Lupi, Matteo, Martinotti, Giovanni, Santacroce, Rita   +6 more
core   +2 more sources

NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES

ChemMedChem, Accepted Article.
Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti, Concetta Altamura, Simone Dell’Atti, Jean-François Desaphy, Ilaria Saltarella   +4 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

How safe are herbal products? [PDF]

, 2000
In the search for cures for his ailments, man discovered many healing and toxic properties of plants. Some were found to cure certain diseases while others were found to exert dramatic effects on the body.
Forte, John Stephen
core  

Acute and long-term effects of brivaracetam and brivaracetam-diazepam combinations in an experimental model of status epilepticus. [PDF]

, 2017
ObjectiveTo evaluate acute and long-term effects of intravenous brivaracetam (BRV) and BRV + diazepam (DZP) combination treatment in a rat model of self-sustaining status epilepticus (SSSE).MethodsRats were treated with BRV (10 mg/kg) 10 min after ...
Alldredge, Biton, Brophy, Chen, Coeytaux, DeLorenzo, FDA, Gezalian, Gillard, Glauser, Griffin, Klein, Klein, Klein, Klitgaard, Klitgaard, Matagne, Matagne, Mazarati, Mazarati, Mazarati, Naylor, Nicolas, Reagan-Shaw, Ryvlin, Sanchez, Silbergleit, Stockis, Suchomelova, Treiman, Trinka, Wasterlain, Wood   +32 more
core   +1 more source

Combined Immediate‐Release and Extended‐Release Formulation of Sodium Valproate Provides Stable Plasma Levels for Inhibition of Histone Deacetylation

Clinical Pharmacology in Drug Development, EarlyView.
Abstract A modified controlled‐release sodium valproate formulation (VAL001, test) was compared with an approved enteric‐coated tablet formulation (Absenor, reference). Pharmacokinetics and safety/tolerability were evaluated in healthy subjects to bridge with positive efficacy results from an early‐phase patient trial of valproate in combination with ...
Nikhil Ahuja, Susanna Kääriäinen, Zsófia Lovró, Mia Lundblad, Kristina Drott, Elsa Lilienberg, Marica T. Engström, Karla Saukkonen, Mika Scheinin   +8 more
wiley   +1 more source

Cannabis Influences the Putative Cytokines-Related Pathway of Epilepsy among Egyptian Epileptic Patients

Brain Sciences, 2019
The study aims to investigate: (1) the prevalence of cannabis among epileptic patients seen at Mansoura University Hospital, (2) serum levels and gene expression of cytokines in epilepsy patients and the controls.
Yasmeen M.Taalab, Wessam Fathi Mohammed, Manar A. Helmy, Alyaa A.A. Othman, Mohamed Darwish, Ibrahim Hassan, Mohammed Abbas   +6 more
doaj   +1 more source

Thin-Layer Chromatography of Anticonvulsant Drugs [PDF]

, 1969
C. E. Pippenger, J. E. Scott, H. W. Gillen   +2 more
openalex   +1 more source

Multigram‐Scale Organic Synthesis by Resonant Acoustic Mixing: Application to the Sustainable Preparation of Active Pharmaceutical Ingredients

ChemSusChem, EarlyView.
Knoevenagel condensation, Biginelli three‐component reaction and benzylic rearrangement are investigated at multi‐gram scale, by resonance acoustic mixing (RAM), to prepare biologically active molecules, also including the marketed Phenytoin (antiepileptic drug). Chem21 and DOZN 3.0 tools were used to assess the greenness of the RAM‐assisted syntheses,
Christos M. Chatzigiannis, Stefania M. Scalzullo, Evelina Colacino, Maria Elena Rivas   +3 more
wiley   +1 more source

Drug interchangeability: Clinical efficacy and safety

Неврология, нейропсихиатрия, психосоматика, 2017
The paper deals with the problem of the interchangeability of brand-name and generic drugs. Touching upon official terminology and the normative documents that govern the registration of generics in Russia and foreign countries, the authors state that ...
S. K. Zyryanov, S. B. Fitilev, I. I. Shkrebneva, A. V. Vozzhaev   +3 more
doaj   +1 more source