Results 311 to 320 of about 3,750,719 (375)
Some of the next articles are maybe not open access.
Drugs, 1984
A considerable amount of information is now available concerning the clinical pharmacology of the anticonvulsant drugs. Some of the more important data are reviewed in this article. In recent years, valproic acid (or sodium valproate) has found a place as a major anticonvulsant agent, while older drugs such as troxidone and sulthiame seem to be ...
openaire +4 more sources
A considerable amount of information is now available concerning the clinical pharmacology of the anticonvulsant drugs. Some of the more important data are reviewed in this article. In recent years, valproic acid (or sodium valproate) has found a place as a major anticonvulsant agent, while older drugs such as troxidone and sulthiame seem to be ...
openaire +4 more sources
Update on Anticonvulsant Drugs
Current Neurology and Neuroscience Reports, 2010In 2009, the US Food and Drug Administration approved three medications for the treatment of epilepsy: rufinamide, lacosamide, and vigabatrin. In addition, extended-release formulations of lamotrigine and levetiracetam were approved recently. When added to the dozen medications for treating epilepsy, the choice is a luxury in terms of additional ...
Carl W. Bazil, Derek J. Chong
openaire +3 more sources
Teratogenicity of anticonvulsant drugs. II: A prospective study.
American journal of medical genetics, 1984To 468 women with epilepsy enrolled in the study, 171 children were born and evaluated prospectively. The mothers in this group were characterized by low socioeconomic status, high frequency of tonic-clonic generalized seizures, and use of combinations ...
Thaddeus E. Kelly +4 more
semanticscholar +1 more source
Interaction of quinidine with anticonvulsant drugs.
New England Journal of Medicine, 1976Drug-disposition studies of orally administered quinidine in four normal healthy volunteers indicated that phenobarbital and phenytoin reduced the half-life of quinidine by approximately 50 per cent (control, 3.0 to 6.1 hours, and with anticonvulsants, 1.
J. Data, G. Wilkinson, A. Nies
semanticscholar +1 more source
1989
Publisher Summary This chapter discusses the biological uses of anticonvulsant drugs. The principal use for anticonvulsant drugs is in the treatment of epilepsy although not all seizures or convulsive states necessarily indicate the presence of epilepsy. Epileptic seizures consist of spontaneous, paroxysmal.
openaire +3 more sources
Publisher Summary This chapter discusses the biological uses of anticonvulsant drugs. The principal use for anticonvulsant drugs is in the treatment of epilepsy although not all seizures or convulsive states necessarily indicate the presence of epilepsy. Epileptic seizures consist of spontaneous, paroxysmal.
openaire +3 more sources
TERATOGENIC EFFECT OF ANTICONVULSANT DRUGS
Obstetrical & Gynecological Survey, 1976Multiple malformations in all four children of a mother taking anticonvulsant drugs are reported, along with the extended family pedigree.
Hans Zellweger +2 more
openaire +4 more sources
A NEW SERIES OF ANTICONVULSANT DRUGS TESTED BY EXPERIMENTS ON ANIMALS
, 1938A method for the determination of the convulsive threshold by means of graded electrical stimulation has been described by Spiegel1and has been employed for comparing the action of certain drugs.
H. Merritt, T. J. Putnam
semanticscholar +1 more source
JAMA: The Journal of the American Medical Association, 1979
THE PAST decade has seen considerable changes in epilepsy management, to which the introduction of new anticonvulsant drugs has contributed. Unfortunately, the ideal drug, one that is long-acting, nonsedative, well-tolerated, useful against various types of seizures, and without a substantive effect on vital organs, while at the same time restoring the
openaire +3 more sources
THE PAST decade has seen considerable changes in epilepsy management, to which the introduction of new anticonvulsant drugs has contributed. Unfortunately, the ideal drug, one that is long-acting, nonsedative, well-tolerated, useful against various types of seizures, and without a substantive effect on vital organs, while at the same time restoring the
openaire +3 more sources
Anticonvulsant Drugs and Cognitive Functions
Epilepsia, 1982Summary: Thirty‐five patients with epilepsy were seen before and 3 and 6 months following changes in their anticonvulsant regimes. Patients either underwent a reduction in the number of different drugs prescribed (n = 20) or had at least one drug changed to carbamazepine (n = 15).
M. R. Trimble, P. J. Thompson
openaire +3 more sources
Plasma 1,25-dihydroxyvitamin D levels in patients receiving anticonvulsant drugs.
Journal of Clinical Endocrinology and Metabolism, 1977Recent evidence has linked altered plasma vitamin D metabolite levels to the reported occurrence of hypocalcemia and other metabolic abnormalities in patients receiving anticonvulsant drugs. We have measured plasma levels of 25-hydroxyvitamin D (25-(OH)D)
W. Jubiz +3 more
semanticscholar +1 more source