Results 31 to 40 of about 3,859,657 (248)

Phenotype-Based Screening of Synthetic Cannabinoids in a Dravet Syndrome Zebrafish Model. [PDF]

open access: yes, 2020
Dravet syndrome is a catastrophic epilepsy of childhood, characterized by cognitive impairment, severe seizures, and increased risk for sudden unexplained death in epilepsy (SUDEP).
Anvar, Mana   +3 more
core   +1 more source

Nootropics use in the workplace. Psychiatric and ethical aftermath towards the new frontier of bioengineering [PDF]

open access: yes, 2020
OBJECTIVE: The authors have sought to expound upon and shed a light on the rise of nootropics, which have gradually taken on a more and more relevant role in workplaces and academic settings.
Bersani, G   +5 more
core   +1 more source

Posterior Reversible Encephalopathy Syndrome and Azathioprine [PDF]

open access: yes, 2019
Posterior reversible encephalopathy syndrome (PRES) is a rare syndrome that presents with neurological manifestations, often associated with arterial hypertension.
Corte-Real, A, Vilas-Boas, S
core   +2 more sources

Anticonvulsant Activity of Halogen-Substituted Cinnamic Acid Derivatives and Their Effects on Glycosylation of PTZ-Induced Chronic Epilepsy in Mice

open access: yesMolecules, 2017
Epilepsy is a common chronic neurological disorder disease, and there is an urgent need for the development of novel anticonvulsant drugs. In this study, the anticonvulsant activities and neurotoxicity of 12 cinnamic acid derivatives substituted by ...
Ye Cuan   +9 more
doaj   +1 more source

Practical considerations in the pharmacological treatment of bipolar disorder

open access: yesSichuan jingshen weisheng, 2023
Bipolar disorder is one of the most common mood disorders characterized by an early age of onset and high prevalence rate, and patients tent to have poor prognosis due to high misdiagnosis rate and incomplete diagnosis rate.
Liu Tiebang
doaj   +1 more source

Design, synthesis, molecular docking and anticonvulsant evaluation of novel 6-iodo-2-phenyl-3-substituted-quinazolin-4(3H)-ones

open access: yesBulletin of Faculty of Pharmacy Cairo University, 2015
A new series of 6-iodo-2-phenyl-3-substituted-quinazolin-4(3H)-one (5–12a–b) derivatives were synthesized, evaluated for their anticonvulsant activity against pentylenetetrazole (PTZ)-induced seizures and maximal electroshock test and compared with the ...
Mohamed-Kamal Ibrahim   +2 more
doaj   +1 more source

Optimal management of seizures associated with tuberous sclerosis complex: current and emerging options. [PDF]

open access: yes, 2014
Seizures are clinically significant manifestations associated with 79%-90% of patients with tuberous sclerosis complex. Often occurring within the first year of life in the form of infantile spasms, seizures interfere with neuropsychiatric, social, and ...
Fallah, Aria, Wang, Shelly
core   +2 more sources

Assessing neurotropic effects of new antiepileptic nitrogen-containing drugs

open access: yesЭпилепсия и пароксизмальные состояния, 2023
Objective: to evaluate an effectiveness of new nitrogen-containing compounds for alleviating epileptiform conditions in animal experimental study, and conduct molecular modeling of a new neurotropic drug.Material and methods.
R. G. Paronikyan   +3 more
doaj   +1 more source

NGX-4010, a capsaicin 8% patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: integrated analysis of two phase III, randomized, controlled trials [PDF]

open access: yes, 2013
BACKGROUND HIV-associated distal sensory polyneuropathy (HIV-DSP) is the most frequently reported neurologic complication associated with HIV infection.
Brew, Bruce J   +9 more
core   +1 more source

Study of anticonvulsant properties of 1,2,4-triazole derivatives and prospects for their use in pharmacy

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
Anticonvulsant drugs (antiepileptic drugs) are a group of medications used to treat epilepsy and to control other disorders associated with seizures or convulsive episodes. The choice of a particular drug depends on the type of seizure, the patient’s age,
N. M. Borysenko   +3 more
doaj   +1 more source

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