Results 31 to 40 of about 3,750,719 (375)

Evaluating the effect of antiepileptic drugs on the function of the thyroid gland of children [PDF]

Cellular, Molecular and Biomedical Reports
Seizures are one of the most important sudden and uncontrolled electrical disorders in the brain, which in acute cases can lead to sudden loss of consciousness and muscle spasms.
Mohamad Hasan Mohamadi, Afsaneh Mirshekari   +1 more
doaj   +1 more source

Screening study of new thiazolidinone derivatives for anticonvulsant activity

Zaporožskij Medicinskij Žurnal, 2020
The search for new antiepileptic drugs that would have greater margins of safety and fewer adverse effects is relevant. Thiazolidinone are a promising class for the development of new anticonvulsants. Aim.
M. V. Mishchenko , S. Yu. Shtrygol, R. B. Lesyk, A. V. Lozynskyi, S. M. Holota   +4 more
doaj   +1 more source

Modulation of neural cell membrane conductance by the herbal anxiolytic and antiepileptic drug aswal [PDF]

, 2000
To evaluate the effects of aswal on ionic fluxes and neuronal excitation, we performed extracellular and whole cell patch clamp recordings on CA1 pyramidal neurons of guinea pigs and Long-Evans rats.
Grunze, Heinz, Langosch, J., Loewenich, C. von, Walden, Jörg   +3 more
core   +1 more source

Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus.

New England Journal of Medicine, 2019
BACKGROUND The choice of drugs for patients with status epilepticus that is refractory to treatment with benzodiazepines has not been thoroughly studied.
J. Kapur, J. Elm, J. Chamberlain, W. Barsan, J. Cloyd, D. Lowenstein, S. Shinnar, R. Conwit, Caitlyn Meinzer, Hannah R Cock, N. Fountain, J. Connor, R. Silbergleit   +12 more
semanticscholar   +1 more source

Zebrafish as a robust preclinical platform for screening plant-derived drugs with anticonvulsant properties—a review

Frontiers in Molecular Neuroscience, 2023
Traditionally, selected plant sources have been explored for medicines to treat convulsions. This continues today, especially in countries with low-income rates and poor medical systems.
Bartosz Knap, Dorota Nieoczym, Uday Kundap, Kamila Kusio-Targonska, Wirginia Kukula-Koch, Waldemar A. Turski, Kinga Gawel   +6 more
doaj   +1 more source

2015 ACVIM Small Animal Consensus Statement on Seizure Management in Dogs [PDF]

, 2016
This report represents a scientific and working clinical consensus statement on seizure management in dogs based on current literature and clinical expertise.
Bunch SE, Bunch SE, Cheuk DK, Cunningham JG, Dayrell‐Hart B, Durkes TE, Dyer KR, E.E. Patterson, Farnbach GC, Farnbach GC, Forrester SD, Frey HH, Gaskill CL, Gaskill CL, H.A. Volk, Jacobs G, Jennings PB, K. Muñana, Kantrowitz LB, M. Berendt, M. Podell, March PA, Masuda Y, Nichols ES, Patterson E, Pearce L, Pedersoli WM, Perrucca E, Poffenbarger EM, Ravis WR, S.R. Platt, Schwartz‐Porsche D, Schwartz‐Porsche D, Steinberg M, Thurman GD, Trepanier LA, Trepanier LA, W. Löscher   +37 more
core   +2 more sources

Effects Of 4-thiazolidinone Derivatives Les-2658 And Les-1205 On Sleep - Wakefulness Cycle In Kindled Rats [PDF]

, 2017
The research is dedicated to in-depth study of neurotrophic and antiepileptic properties of original potential anticonvulsant agents from 4-thiazolidinones – LES-2658 (5-(3-nitro-benzylidene)-2-(thiazol-2-ylimino)-thiazolidin-4-one) and LES-1205 ([2,4 ...
Lesyk, R. (Roman), Myronenko, S. (Solomija), Pinyazhko, O. (Oleh)   +2 more
core   +2 more sources

Nitrogen‐Centered Organic Persistent Radicals Catalyze Redox‐Neutral C─C Bond Forming Reactions

Angewandte Chemie, EarlyView.
Kuhn verdazyls, discovered over 60 years ago, are shown as effective catalysts for the first time. Their tunable redox properties enable organocatalytic redox‐neutral C─H arylation and C─H trifluoromethylation reactions without light activation.
Shrouq Mujahed, Jaysan Janabel, Kundan Shaw, Roberta Cagliani, Tynchtyk Amatov   +4 more
wiley   +2 more sources

Phenotype-Based Screening of Synthetic Cannabinoids in a Dravet Syndrome Zebrafish Model. [PDF]

, 2020
Dravet syndrome is a catastrophic epilepsy of childhood, characterized by cognitive impairment, severe seizures, and increased risk for sudden unexplained death in epilepsy (SUDEP).
Anvar, Mana, Baraban, Scott C, Griffin, Aliesha, Hamling, Kyla   +3 more
core   +1 more source

Phytocannabinoids as novel therapeutic agents in CNS disorders [PDF]

, 2012
The Cannabis sativa herb contains over 100 phytocannabinoid (pCB) compounds and has been used for thousands of years for both recreational and medicinal purposes.
Hill, Andrew J., Stephens, Gary J., Whalley, Benjamin J., Williams, Claire M.   +3 more
core   +1 more source