Results 161 to 170 of about 44,397 (250)

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Brainwaves under medication: revealing class-specific neural signatures of psychotropic medication from 24,000 EEGs. [PDF]

EBioMedicine
Szponar M, Dzianok P, Gmaj B, Jernajczyk W, Kamiński J.   +4 more
europepmc   +1 more source

Prophylactic antiseizure medication administration practices in neonates with hypoxic-ischaemic encephalopathy: a scoping review protocol. [PDF]

BMJ Open
Nalwanga LE, Ayesiga I, Ediamu TD.
europepmc   +1 more source

Bortezomib‐based chemotherapy in Chinese pediatric patients with relapsed/refractory acute lymphoblastic leukemia: A single‐center retrospective study

Pediatric Investigation, EarlyView.
Bortezomib‐based chemotherapy achieved an 88.9% remission rate in Chinese pediatric patients with relapsed/refractory B‐cell acute lymphoblastic leukemia, enabling 62.5% of responders to bridge to transplantation, while T‐cell acute lymphoblastic leukemia showed no response.
Xingyu Zhao, Jian Wang, Liping Que, Dunhua Zhou, Jianpei Fang, Luhong Xu   +5 more
wiley   +1 more source

Editorial: Experimental Models of Epilepsy and Related Comorbidities

Frontiers in Pharmacology, 2019
Ayanabha Chakraborti, Mohd. Farooq Shaikh, Annamaria Vezzani, Jafri Malin Abdullah   +3 more
doaj   +1 more source

Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting

PM&R, EarlyView.
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy, Joshua C. Wiener, Karen Pratt, Laura Brunton   +3 more
wiley   +1 more source

Hypovitaminosis D in acute inpatient cancer rehabilitation: Prevalence, predictors, and practical implications

PM&R, EarlyView.
Abstract Background Hypovitaminosis D is associated with adverse health outcomes, including increased mortality in patients with cancer. Although vitamin D insufficiency (23%–72%) and deficiency (20%–71%) are common among patients admitted to inpatient rehabilitation, their prevalence and predictors in cancer‐specific inpatient rehabilitation ...
Jegy M. Tennison, Minxing Chen, Areeba Hafeez, Ananya Krishnan, Sefia Khan, Rony Dev, Sonal Admane, Eduardo Bruera   +7 more
wiley   +1 more source

Modulation of Endoplasmic Reticulum Stress via CEBPB: A Potential Molecular Link to Therapeutic Action in Substance Use Disorders. [PDF]

CNS Neurosci Ther
Zhang C, Li H, Ho MF.
europepmc   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source

Potential value of slow‐wave sleep in management of chronic insomnia disorder

Sleep Research, EarlyView.
Abstract Chronic insomnia disorder (CID), acknowledged as the most common sleep disorder, has traditionally been diagnosed and managed with a focus on reducing sleep onset latency and extending total sleep duration. However, the critical importance of slow‐wave sleep (SWS), a key indicator of objective sleep quality, has been largely overlooked in ...
Liping Zhang, Qi Wu, Mengmeng Fan, Xianchao Zhao, Changjun Su   +4 more
wiley   +1 more source