Results 11 to 20 of about 105,937 (401)

Prophylactic Anticonvulsants in Intracerebral Hemorrhage [PDF]

open access: yesNeurocritical Care, 2017
Background and Purpose Prophylactic anticonvulsants are routinely prescribed in the acute setting for intracerebral hemorrhage (ICH) patients, but some studies have reported an association with worse outcomes.
J. Mackey   +10 more
semanticscholar   +3 more sources

Familial Bainbridge‐Ropers syndrome: Report of familial ASXL3 inheritance and a milder phenotype

open access: yesAmerican Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 29-36, January 2023., 2023
Abstract De novo truncating and splicing pathogenic variants in the Additional Sex Combs‐Like 3 (ASXL3) gene are known to cause neurodevelopmental delay, intellectual disability, behavioral difficulties, hypotonia, feeding problems and characteristic facial features.
Schaida Schirwani   +10 more
wiley   +1 more source

Genetic and phenotypic spectrum in the NONO‐associated syndromic disorder

open access: yesAmerican Journal of Medical Genetics Part A, Volume 191, Issue 2, Page 469-478, February 2023., 2023
Abstract The non‐POU domain‐containing octamer‐binding (NONO) protein is involved in multiple steps of gene regulation such as RNA metabolism and DNA repair. Hemizygous pathogenic variants in the NONO gene were confirmed to cause a rare X‐linked syndromic disorder. Through our in‐house diagnostics and subsequent matchmaking, we identified six unrelated
Franziska Roessler   +21 more
wiley   +1 more source

Anticonvulsants in neuropathic pain: rationale and clinical evidence

open access: yesEuropean Journal of Pain, 2002
Troels Staehelin Jensen, Dirk J Duncker
exaly   +2 more sources

Comparative vascular effects of levetiracetam and valproate with hyperhomocysteinemia in rat models

open access: yesTürk Biyokimya Dergisi, 2023
Hyperhomocysteinemia (HHcy) a significant risk factor for vascular disease, often emerges in epilepsy with the use of antiepileptic drugs. In this relationship, our study investigates the combined effects of HHcy and antiepileptics on vascular function ...
Gökdemir Selim   +6 more
doaj   +1 more source

Role of Anticonvulsants in the Management of AIDS related Seizures

open access: yesFrontiers in Neurology, 2014
Seventy percent of the AIDS patients have neurological complications. Seizures are one of the complications and can occur at any stage. Seizures can be life–threatening and treatment with anticonvulsants is warranted.
BATOOL F. KIRMANI   +1 more
doaj   +1 more source

Anticonvulsants in the treatment of low back pain and lumbar radicular pain: a systematic review and meta-analysis

open access: yesCanadian Medical Association Journal, 2018
BACKGROUND: The use of anticonvulsants (e.g., gabapentin, pregabalin) to treat low back pain has increased substantially in recent years despite limited supporting evidence.
Oliver Enke   +7 more
semanticscholar   +1 more source

Early Administration of Gabapentinoids Improves Motor Recovery after Human Spinal Cord Injury

open access: yesCell Reports, 2017
The anticonvulsant pregabalin promotes neural regeneration in a mouse model of spinal cord injury (SCI). We have also previously observed that anticonvulsants improve motor outcomes following human SCI.
Freda M. Warner   +10 more
doaj   +1 more source

Cognitive Effects of Anticonvulsants

open access: yesPediatric Neurology Briefs, 1990
The neuropsychological effects of carbamazepine, phenobarbital, and phenytoin in 15 patients with partial complex epilepsy were investigated at the Department of Neurology, Medical College of Georgia, Augusta, GA.
J Gordon Millichap
doaj   +1 more source

Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants

open access: yesThe Journal of General Physiology, 2017
Local anesthetics, antiarrhythmics, and anticonvulsants include both charged and electroneutral compounds that block voltage-gated sodium channels. Prior studies have revealed a common drug-binding region within the pore, but details about the binding ...
D. Tikhonov, B. Zhorov
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy