Results 191 to 200 of about 43,686 (290)

High Doses of Melatonin Induce Seizure-like Cortical Activity: Electrophysiological and Behavioral Evidence. [PDF]

ACS Omega
Almeida L, Lins A, Eiró-Quirino L, de Souza LV, Hamoy MKO, Hartcoff PFP, Brito MVDS, Barbosa GB, Reis TS, Hamoy M.   +9 more
europepmc   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source

Visible‐light‐promoted catalyst‐free benzylic C‐H oxidation using molecular oxygen as a green oxidant

Smart Molecules, EarlyView.
A green and simple photo‐oxygenation of benzylic C‐H bond with molecular oxygen was developed for the preparation of a series of carbonyl compounds. The straightforward C‐H carbonylation strategy features catalyst‐ and additive‐free reaction conditions, only oxygen as a green oxidant, broad scope and scalable, and the simple‐operation nature.
Jianing Li, Suwen Wang, Huinan Sun, Zhunchao Liu, Xiangmin Tian, Qilei Liu, Qingwei Meng   +6 more
wiley   +1 more source

Sturge-Weber Syndrome: A Rare Clinical Presentation with Bilateral Port-Wine Stain and Leptomeningeal Angiomatosis. [PDF]

Indian J Dermatol
Gomes LLA, de Castro VB, Thien CI, de Oliveira Vieira E, Azulay-Abulafia L.   +4 more
europepmc   +1 more source

Comparative Efficacy of Elinzanetant Versus Other Non‐Hormonal Pharmaceutical Therapies for the Treatment of Moderate‐to‐Severe Vasomotor Symptoms Associated With Menopause: A Network Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Elinzanetant, a novel, dual neurokinin‐targeted therapy, has been approved in various geographies for the treatment of moderate‐to‐severe vasomotor symptoms (VMS) associated with menopause. Objective To compare the efficacy of elinzanetant with non‐hormonal pharmaceutical treatments (nHT) in alleviating VMS.
Piotr Wojciechowski, Klaudia Kolonko, Andromachi Giannopoulou, Beata Smela, Elżbieta Olewinska, Kristina Rosa Bolling, Jenifer Sassarini, Lee P. Shulman, Vikram Talaulikar   +8 more
wiley   +1 more source

Antibody-drug conjugates in brain metastases: evidence outpacing trial design. [PDF]

ESMO Open
Sarfraz Z, Tarantino P, Mahtani R, Ahluwalia MS.   +3 more
europepmc   +1 more source

Lithium Use in Pregnancy and the Risk of Spontaneous Preterm Birth: An Australian Statewide Retrospective Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To investigate whether lithium exposure in pregnancy is associated with spontaneous preterm birth, congenital malformations and abnormal fetal growth. Design Statewide retrospective cohort study. Setting Victoria, Australia. Population 867 454 births (2009–2020), including 234 (0.03%) exposed to lithium during pregnancy.
Alexandra Roddy Mitchell, Anthea Lindquist, Richard J. Hiscock, Anna Forsythe, Hannah Gordon, Caroline S. E. Homer, Natasha Pritchard, Jessica Atkinson, Susan P. Walker, Stephen Tong, Roxanne Hastie   +10 more
wiley   +1 more source

Psychotropic medication use and bone loss in men: longitudinal study. [PDF]

BJPsych Open
Weerasinghe DK, Stuart AL, Pasco JA, Mohebbi M, Hodge JM, Samarasinghe RM, Williams LJ.   +6 more
europepmc   +1 more source