Results 281 to 290 of about 111,563 (381)

Low back pain and radicular pain : assessment and management [PDF]

open access: yes, 2017
Ailiet, Luc   +23 more
core   +1 more source

Pharmacokinetics and tolerability of single‐dose Staccato® alprazolam in adolescents with epilepsy, and population pharmacokinetic analysis to support dose selection in adolescents

open access: yesEpilepsia, EarlyView.
This is a graphical representation of the abstract and article highlights. Abstract Objective Staccato® alprazolam is a hand‐held inhalation device that provides rapid systemic delivery of alprazolam through the intrapulmonary route. This trial explored the pharmacokinetics and tolerability of single‐dose Staccato alprazolam 2 mg in adolescents with ...
Pavel Klein   +12 more
wiley   +1 more source

Artificial intelligence‐driven closed‐loop devices in sudden unexpected death in epilepsy prediction and prevention: Insights from persons with epilepsy and caregivers

open access: yesEpilepsia, EarlyView.
Abstract Objective The absence of strategies for predicting and preventing sudden unexpected death in epilepsy (SUDEP) is intertwined with the lack of studies measuring users' attitudes toward potential innovative interventions. The NEUROSENSE Project (http://www.neurosense‐project.eu) aims to evaluate novel SUDEP‐predictive neuroendocrine biomarkers ...
João Ferreira   +16 more
wiley   +1 more source

Synthesis, Anticonvulsant, Antinociceptive Activity and Preliminary Safety Evaluations of Novel Hybrid Imidazolidine‐2,4‐Dione Derivatives with Morpholine Moiety

open access: green
Anna Czopek   +8 more
openalex   +2 more sources

Respiratory dysfunction and fatal apnea during pilocarpine‐induced status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is second only to sudden unexpected death in epilepsy as a cause of seizure‐related mortality. The progression of respiratory dysfunction during experimental SE remains poorly characterized. We investigated how pilocarpine‐induced SE affects respiration in mice.
Chengsan Sun   +6 more
wiley   +1 more source

Visualizing Real-World Pain Treatment Pathways in Chronic Disease: A Sequence-Based Analysis of Polypharmacy in Systemic Lupus Erythematosus. [PDF]

open access: yesACR Open Rheumatol
Le N   +8 more
europepmc   +1 more source

Family Game Show-style Didactic for Teaching Nervous System Disorders during Emergency Medicine Training [PDF]

open access: yes, 2020
Boysen Osborn, Megan   +3 more
core  

C1q neutralization during epileptogenesis attenuates complement‐mediated synaptic elimination and epileptiform activity

open access: yesEpilepsia, EarlyView.
Abstract Objective Accumulating evidence indicates that aberrant C1q‐C3 complement signaling in microglia and astrocytes drives synaptic dysfunction and neuronal loss. C1q‐mediated synaptic dysfunction disrupts neuronal circuitry balance and can lead to network hyperexcitability in epilepsy.
Yoonyi Jeong   +5 more
wiley   +1 more source

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