Results 21 to 30 of about 108,057 (400)

Screening of conventional anticonvulsants in a genetic mouse model of epilepsy

open access: yesAnnals of Clinical and Translational Neurology, 2017
Epilepsy is a common neurological disorder that affects 1% of the population. Approximately, 30% of individuals with epilepsy are refractory to treatment, highlighting the need for novel therapies.
N. Hawkins   +5 more
semanticscholar   +1 more source

Neuropsychological Effects of Anticonvulsants

open access: yesPediatric Neurology Briefs, 2015
Investigators from 7 centers in Korea conducted a prospective, multicenter study with patients randomized into two open-label, parallel groups and treated with either levetiracetam (LVT) or carbamazepine (CBZ) monotherapy for newly diagnosed focal ...
Lindsey Morgan, Alexandra Shaw
doaj   +1 more source

Cognitive Effects of Anticonvulsants

open access: yesPediatric Neurology Briefs, 1990
The neuropsychological effects of carbamazepine, phenobarbital, and phenytoin in 15 patients with partial complex epilepsy were investigated at the Department of Neurology, Medical College of Georgia, Augusta, GA.
J Gordon Millichap
doaj   +1 more source

Antiepileptic drugs reduce serum uric acid [PDF]

open access: yes, 1987
Uric acid examination in 554 epileptic out-patients under long-term anticonvulsant medication revealed significantly lower serum concentrations compared to a group of normal controls.
Arab   +7 more
core   +1 more source

Multidrug Cocrystal of Anticonvulsants: Influence of Strong Intermolecular Interactions on Physiochemical Properties.

open access: yesCrystal Growth & Design, 2017
A drug-drug cocrystal of two anticonvulsants, lamotrigine and phenobarbital, is presented. In the crystal structure, molecules form heterodimers via N-H···O and N-H···N hydrogen bonding.
R. Kaur   +3 more
semanticscholar   +1 more source

New Anticonvulsants: Interchangeability Issues and the Use of Generic Anticonvulsants in Clinical Practice

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2019
This article looks into interchangeability and therapeutic equivalence of innovator and generic anticonvulsants — the first-generation and new antiepileptic drugs (AEDs).
V. V. Arkhipov   +4 more
doaj   +1 more source

Cyclic Vomiting Syndrome in Children

open access: yesFrontiers in Neurology, 2020
Cyclic Vomiting Syndrome (CVS) is an underdiagnosed episodic syndrome characterized by frequent hospitalizations, multiple comorbidities, and poor quality of life.
Umberto Raucci   +29 more
doaj   +1 more source

Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket

open access: yesNature Communications, 2018
Epilepsy has been treated for centuries with herbal remedies, including leaves of the African shrub Mallotus oppositifolius, yet the underlying molecular mechanisms have remained unclear.
Rían W. Manville, G. Abbott
semanticscholar   +1 more source

Status Epilepticus and Beyond: A Clinical Review of Status Epilepticus and an Update on Current Management Strategies in Super-refractory Status Epilepticus [PDF]

open access: yesKorean Journal of Critical Care Medicine, 2017
Status epilepticus and refractory status epilepticus represent some of the most complex conditions encountered in the neurological intensive care unit. Challenges in management are common as treatment options become limited and prolonged hospital courses
Roy Poblete, Gene Sung
doaj   +1 more source

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