Results 81 to 90 of about 105,937 (401)

Emerging pharmacotherapy of tinnitus [PDF]

open access: yes, 2009
Tinnitus, the perception of sound in the absence of an auditory stimulus, is perceived by about 1 in 10 adults, and for at least 1 in 100, tinnitus severely affects their quality of life.
Ana Belén Elgoyhen   +43 more
core   +1 more source

A companion to the preclinical common data elements for phenotyping seizures and epilepsy in rodent models. A report of the TASK3‐WG1C: Phenotyping working group of the ILAE/AES joint translational task force

open access: yesEpilepsia Open, EarlyView., 2022
Abstract Epilepsy is a heterogeneous disorder characterized by spontaneous seizures and behavioral comorbidities. The underlying mechanisms of seizures and epilepsy across various syndromes lead to diverse clinical presentation and features. Similarly, animal models of epilepsy arise from numerous dissimilar inciting events.
Melissa Barker‐Haliski   +3 more
wiley   +1 more source

Pain management and stroke prevention in HHV-3-associated infection

open access: yesКлиническая практика, 2019
The modern information on the epidemiology, pathogenesis, clinical manifestations, diagnosis and pain management in HHV-3-associated neuro-infection is presented. The criteria for the phased diagnostics and approaches to the rational therapy for shingles
O. V. Kolokolov   +6 more
doaj   +1 more source

Headaches [PDF]

open access: yes, 2006
A 30 year old lady was seen by her family doctor during a busy clinic complaining of three episodes of left-sided headache over the previous four months.
Camilleri, Myriam
core   +1 more source

Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain. An observational analysis [PDF]

open access: yes, 2016
INTRODUCTION: Cancer-related pain has a severe negative impact on quality of life. Combination analgesic therapy with oxycodone and pregabalin is effective for treating neuropathic cancer pain.
Borghesi, Cristina   +6 more
core   +2 more sources

Enaminone‐Based Push–Pull Chromophores: Synthesis, Optical Properties, and Computational Insights

open access: yesAsian Journal of Organic Chemistry, EarlyView.
Enaminones, known for their pharmacophoric properties, were combined with alkyne units to create complex chromophore structures through click‐type [2 + 2] cycloaddition‐retroelectrocyclization reactions. The ICT characteristics of the synthesized compounds were analyzed using both experimental and computational approaches.
Mehmet Mart   +2 more
wiley   +1 more source

Sodium valproate induced necrotising pancreatitis: A case report [PDF]

open access: yesMalaysian Family Physician, 2013
Sodium valproate is one of the most common first-line antiepileptics prescribed for primary and secondary generalised seizures. However, serious complications associated with sodium valproate, such as acute pancreatitis, need to be considered when ...
Mohd Fairuz Ali, Loh Keng Yin
doaj  

Toxic Epidermal Necrolysis after Pemetrexed and Cisplatin for Non-Small Cell Lung Cancer in a Patient with Sharp Syndrome [PDF]

open access: yes, 2012
Background: Pemetrexed is an antifolate drug approved for maintenance and second-line therapy, and, in combination with cisplatin, for first-line treatment of advanced nonsquamous non-small cell lung cancer.
Aguiar D   +28 more
core   +1 more source

Animal models of cisplatin‐induced neuropathic pain

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This article illustrates the modeling process of a cisplatin‐induced neuropathic pain model in rats or mice. Multiple modeling tests are required for rats or mice before, during, and after modeling. The appropriate injection method, dose, and modeling method are selected, and multiple assays are chosen for evaluation and comparison.
Ningxin Li   +9 more
wiley   +1 more source

Status epilepticus: modern views on classification, typology, methods of diagnosis and treatment with third-generation anticonvulsants (review)

open access: yesМедицина неотложных состояний
Status epilepticus (SE) is a medical emergency associated with high morbidity and mortality. The guidelines of the International League Against Epilepsy use a stepwise approach to the treatment of SE depending on the response to treatment ...
L.B. Maryenko   +2 more
doaj   +1 more source

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