Results 81 to 90 of about 46,422 (312)

Epilepsy and pregnancy

open access: yesНеврология, нейропсихиатрия, психосоматика
There are currently about 15 million women of childbearing age worldwide who suffer from epilepsy. Overall, 0.3–0.4% of newborns are born to mothers with epilepsy, and almost half of these women experience recurrent seizures. The article discusses issues
P. N. Vlasov   +3 more
doaj   +1 more source

Thin-Layer Chromatography of Anticonvulsant Drugs [PDF]

open access: bronze, 1969
C. E. Pippenger   +2 more
openalex   +1 more source

Multigram‐Scale Organic Synthesis by Resonant Acoustic Mixing: Application to the Sustainable Preparation of Active Pharmaceutical Ingredients

open access: yesChemSusChem, EarlyView.
Knoevenagel condensation, Biginelli three‐component reaction and benzylic rearrangement are investigated at multi‐gram scale, by resonance acoustic mixing (RAM), to prepare biologically active molecules, also including the marketed Phenytoin (antiepileptic drug). Chem21 and DOZN 3.0 tools were used to assess the greenness of the RAM‐assisted syntheses,
Christos M. Chatzigiannis   +3 more
wiley   +1 more source

Multianalyte Approach—Including Automated Preparation of Calibrators—for Validated Quantification of 82 Drugs in Whole Blood by Liquid Chromatography–Tandem Mass Spectrometry

open access: yesDrug Testing and Analysis, EarlyView.
In forensic bioanalysis, often multianalyte approaches are used given their increased effectiveness but can be difficult to develop and maintain in the laboratory, for example, in terms of calibrator solution preparation. A fast, simple, and robust liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for the quantification of 82 classic ...
Andrea E. Steuer   +3 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

open access: yes, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

The study of risk factors for osteoporosis with prolonged use of anticonvulsants: intermediate results

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева
The mechanisms of anticonvulsant effects on bone metabolism are not studied sufficiently. This determines the relevance of research on factors that influence the development of osteoporosis in patients taking long-term anticonvulsants.
N. A. Sivakova   +8 more
doaj   +1 more source

Waxy‐ or Putty‐Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity

open access: yesDrug Testing and Analysis, EarlyView.
Waxy‐ or putty‐like materials has emerged as a novel drug preparation for synthetic cannabinoids and other drugs in UK prisons. An in vitro CB1 bioassay was used to evaluate the CB1 activating potential of MDMB‐INACA and extracts from eight seized samples. MDMB‐INACA had moderate efficacy but low potency at CB1.
Axelle Timmerman   +9 more
wiley   +1 more source

Anticonvulsants impacting bone metabolism: interim results from a cross-sectional study

open access: yesЭпилепсия и пароксизмальные состояния
Background. Despite a wide range of antiepileptic drugs (AEDs) with an improved pharmacological profile, patients often experience a variety of side effects during long-trem anticonvulsant therapy, among which are osteoporotic disorders.
N. A. Sivakova   +7 more
doaj   +1 more source

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