Results 41 to 50 of about 44,755 (247)

Anticorps monoclonaux thérapeutiques [PDF]

open access: yesmédecine/sciences, 2019
Les anticorps monoclonaux thérapeutiques en dermatologie ont d’abord été utilisés pour la prise en charge du psoriasis, puis, plus récemment, de l’urticaire chronique spontanée et de la dermatite atopique. Trois exemples seront abordés dans cette revue: le dupilumab, l’omalizumab et le lanadélumab.
Aurélie Du-Thanh, Bernard Guillot
openaire   +1 more source

Péripneumonie contagieuse bovine : test immunoenzymatique et cinétique d'apparition des anticorps au cours d'une infection expérimentale. Relation entre la fixation du complément, l'excrétion et la recherche de l'antigène circulant

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1989
Un protocole d'infection expérimentale de la péripneumonie contagieuse bovine a été mis en place et les animaux ont fait l'objet d'un suivi sérologique sur quatre mois. Le test immunoenzymatique IgG présenté dose les anticorps, avec un retard de quelques
Christian Le Goff   +1 more
doaj   +1 more source

Anticorps et bioterrorisme [PDF]

open access: yesmédecine/sciences, 2009
Le risque d’utilisation d’armes biologiques pourrait conduire a la reemergence de graves pathologies, telles que la peste ou la variole, maintenant eradiquees des pays developpes. La prise en charge de ce risque, appele risque biologique provoque (RBP), comporte notamment le developpement d’anticorps recombinants - qui est une voie assez sure pour ...
Philippe Thullier   +2 more
openaire   +1 more source

Expression and ultrastructural localization of plasmin(ogen) in the terminally differentiated layers of normal human epidermis

open access: yesInternational Journal of Cosmetic Science, Volume 41, Issue 6, Page 624-628, December 2019., 2019
There exists a paucity of data on the subcellular localization of plasmin(ogen) within normal human epidermis. Immunoelectron transmission electron microscopy labelling revealed that the inflammatory serine protease is located in the terminally differentiated keratinocytes and was largely associated with the corneocyte envelopes and to some extent with
R. Voegeli, A.V. Rawlings, M. Haftek
wiley   +1 more source

Evaluation des tests immune-enzymatiques de détection des antigènes au moyen des anticorps mono- et polyclonaux pour le diagnostic de l’infection à Trypanosoma evansi chez le dromadaire (Camelus dromedarius)

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1992
L'aptitude de deux tests ELISA d'absorption immuno-enzymatique utilisant, l'un un anticorps monoclonal spécifique anti-Trypanosoma brucei obtenu sur souris, l'autre des anticorps polyclonaux spécifiques de Trypanosoma evansi produits sur lapin, a été ...
O. Diall   +4 more
doaj   +1 more source

Bispecific nanobody® as a new pharmacological drug for the selective inhibition of Trypsin‐3

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 19, Page 4578-4591, October 2025.
Abstract Background and Purpose Proteolytic balance is dysregulated in many diseases, with proteases playing critical roles in pathological pathways. A high level of Trypsin‐3 expression has been implicated as a significant mediator of tumour progression and metastasis, and this protease is associated with poor prognosis for patients in various cancers.
Melissa David   +9 more
wiley   +1 more source

Canadian Public Health Laboratory Network laboratory Guidelines for the Diagnosis of Neurosyphilis in Canada

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, Volume 26, Issue A, Page 18A-22A, 2015., 2015
Neurosyphilis refers to infection of the central nervous system by Treponema pallidum, which may occur at any stage. Neurosyphilis has been categorized in many ways including early and late, asymptomatic versus symptomatic and infectious versus non‐infectious. Late neurosyphilis primarily affects the central nervous system parenchyma, and occurs beyond
Tom Wong   +5 more
wiley   +1 more source

Detection of antibodies to Cowdria ruminantium in the serum of domestic ruminants by indirect ELISA [PDF]

open access: yes, 1993
Un test ELISA a été mis au point pour la détection d'anticorps contre Cowdria ruminantium dans le sérum de ruminants domestiques. Les micro-organismes cultivés dans des cellules bovines endothéliales ombilicales ont été utilisés comme antigène.
Coisne, S.   +3 more
core  

Updated insights into the molecular pathogenesis of canine atopic dermatitis

open access: yesVeterinary Dermatology, Volume 36, Issue 4, Page 375-384, August 2025.
Abstract Atopic dermatitis (AD) is a common and chronic inflammatory skin disease with frequent relapses. The genomics revolution has greatly contributed and revolutionised our knowledge of human AD; understanding the molecular skin fingerprint of AD and associated pathogenic immune pathways has led to preclinical assessments of several novel ...
Frane Banovic
wiley   +1 more source

Cutaneous Sarcoidosis in a Patient with Severe Asthma treated with Omalizumab

open access: yesCanadian Respiratory Journal, Volume 22, Issue 6, Page 315-316, 2015., 2015
Omalizumab, a monoclonal anti‐immunoglobulin E antibody, has been used as an effective treatment for severe asthma associated with atopy over the past decade. Sarcoidosis is an idiopathic granulomatous disorder in which first‐line treatment is usually glucocorticoids.
Samuel Yung, Duhyun Han, Jason K Lee
wiley   +1 more source

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