Unmasking the tumourigenic role of SIN1/MAPKAP1 in the mTOR complex 2. [PDF]
SIN1 is a cornerstone subunit of mTORC2, stabilizing the complex and regulating its substrate specificity. SIN1 upregulation and overexpression are associated with many types of cancer and drive tumourigenesis. SIN1 is connected with other signaling pathways disrupted in cancer: Hippo, WNT, Notch, RAS and MAPK.
Ezine E, Lebbe C, Dumaz N.
europepmc +2 more sources
Developing small Cas9 hybrids using molecular modeling
Mangin A, Dion V, Menzies G.
europepmc +1 more source
Echocardiographic correlation of right ventricular-Pulmonary artery coupling to exercise tolerance in congenital heart disease-associated pulmonary hypertension. [PDF]
Ratri AK +7 more
europepmc +1 more source
Impact on increasing the bent angle in nickel dibenzoporphyrin(2.1.2.1) bows. Evaluation of structural and molecular features from computations. [PDF]
Paco-Chipana M, Muñoz-Castro A.
europepmc +1 more source
Essential and Toxic Mineral Content and Fatty Acid Profile of Colostrum in Dairy Sheep. [PDF]
Guiso MF +8 more
europepmc +1 more source
Walking to work: The role of walkability around the workplace in a Dutch adult commuting population. [PDF]
Osmënaj T +3 more
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Semen Quality in Rams Is Severely but Temporarily Affected by Bluetongue Virus Serotype 3 Infection. [PDF]
Martinelle L +5 more
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Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD. [PDF]
Lee S +13 more
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