Results 11 to 20 of about 15,207 (293)

Integration of production and financial models to analyse the financial impact of livestock diseases: a case study of Schmallenberg virus disease on British and French dairy farms [PDF]

open access: yesVeterinary Record Open, Volume 2, Issue 1, January 2015., 2015
AIMS AND OBJECTIVES: The aim of the study was to investigate and compare the financial impact of Schmallenberg disease for different dairy production types in the United Kingdom and France.
Alarcon, P   +4 more
core   +3 more sources

Minimizing carry-over PCR contamination in expanded CAG/CTG repeat instability applications. [PDF]

open access: yesSci Rep, 2017
Expanded CAG/CTG repeats underlie the aetiology of 14 neurological and neuromuscular disorders. The size of the repeat tract determines in large part the severity of these disorders with longer tracts causing more severe phenotypes.
Aeschbach L, Dion V.
europepmc   +6 more sources

Adaptation des systèmes d’élevage ovin aux changements climatiques : impacts sur la composante pastorale dans le Haut Atlas central du Maroc [PDF]

open access: goldAgricultures
Les changements climatiques constituent une menace sérieuse pour les ressources pastorales, dégradant les parcours et impactant les populations qui en dépendent.
Soufiane El Aayadi   +5 more
openalex   +2 more sources

The Seizure-Associated Genes Across Species (SAGAS) database offers insights into epilepsy genes, pathways and treatments. [PDF]

open access: yesEpilepsia, 2022
Abstract Objective Decades of genetic studies on people with many different epilepsies, and on many nonhuman species, using many different technologies, have generated a huge body of literature about the genes associated with seizures/epilepsy. Collating these data can help uncover epilepsy genes, pathways, and treatments that would otherwise be ...
Gracie L   +4 more
europepmc   +2 more sources

Statins as antiepileptogenic drugs: Analyzing the evidence and identifying the most promising statin. [PDF]

open access: yesEpilepsia, 2022
Abstract Many brain insults and injuries are “epileptogenic”: they increase the risk of developing epilepsy. It is desirable to identify treatments that are “antiepileptogenic”: treatments that prevent the development of epilepsy, if administered after the occurrence of an epileptogenic insult. Current antiepileptic drugs are not antiepileptogenic, but
Hufthy Y   +12 more
europepmc   +2 more sources

Unmasking the tumourigenic role of SIN1/MAPKAP1 in the mTOR complex 2. [PDF]

open access: yesClin Transl Med, 2023
SIN1 is a cornerstone subunit of mTORC2, stabilizing the complex and regulating its substrate specificity. SIN1 upregulation and overexpression are associated with many types of cancer and drive tumourigenesis. SIN1 is connected with other signaling pathways disrupted in cancer: Hippo, WNT, Notch, RAS and MAPK.
Ezine E, Lebbe C, Dumaz N.
europepmc   +2 more sources

Assessment of information as regards the toxicity of T-2 and HT-2 toxin for ruminants. [PDF]

open access: yesEFSA J, 2022
Abstract In 2011, the EFSA Panel on Contaminants in the Food Chain (CONTAM) adopted a Scientific Opinion on the risks for animal health related to the presence of T‐2 (T2) and HT‐2 (HT2) toxin in food and feed. No observed adverse effect levels (NOAELs) and lowest observed adverse effect levels (LOAELs) were derived for different animal species.
EFSA Panel on Contaminants in the Food Chain (CONTAM)   +21 more
europepmc   +2 more sources

The Inflation Reduction Act: A boon for the generic and biosimilar industry. [PDF]

open access: yesJ Clin Pharm Ther, 2022
The Inflation Reduction Act gives a significant boost to generics and biosimilars!Soon lowered out‐of‐pocket costBiosimilars promoted and adopted Abstract What is Known and Objective After more than a year of negotiation, a $740 billion climate and health care bill known as The Inflation Reduction Act (IRA) became law on 16 August 2022.
Niazi SK.
europepmc   +2 more sources

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