Results 11 to 20 of about 78,261 (230)

Cytokine transcriptome profiling in acute experimental canine atopic dermatitis skin lesions after IL‐31 inhibition with lokivetmab

open access: yesVeterinary Dermatology, Volume 34, Issue 4, Page 327-338, August 2023., 2023
Background – The caninised monoclonal antibody lokivetmab (LKV), directed at interleukin (IL)‐31, is very effective at controlling pruritus in most dogs with atopic dermatitis (AD). However, evidence exists that IL‐31 is not required for the induction of acute allergic skin inflammation, which might explain why this treatment is less efficacious in ...
Chie Tamamoto‐Mochizuki   +4 more
wiley   +1 more source

A masked, randomised clinical trial evaluating the efficacy and safety of lokivetmab compared to saline control in client‐owned dogs with allergic dermatitis

open access: yesVeterinary Dermatology, Volume 32, Issue 5, Page 477-e131, October 2021., 2021
Background – Interleukin (IL)‐31 is an important mediator in canine atopic dermatitis (cAD) and also may be dysregulated in other allergic diseases. Hypothesis/Objectives – To demonstrate the efficacy and safety of lokivetmab (canine anti‐IL‐31 monoclonal antibody) for treatment of pruritus associated with allergic dermatitis in dogs.
Leen Van Brussel   +4 more
wiley   +1 more source

Immunopathogenesis of the feline atopic syndrome

open access: yesVeterinary Dermatology, Volume 32, Issue 1, Page 13-e4, February 2021., 2021
Résumé Contexte Les maladies félines supposées d’origine allergique avec des phénotypes cliniques semblables, peuvent avoir de nombreuses pathogénies différentes sous jacentes. Le phénotype clinque, l’étiologie précise et l’immunopathogénie sous jacente doivent tous être considérés si des avancées veulent être faites dans ces domaines négligés de la ...
Richard Halliwell   +3 more
wiley   +1 more source

Serum canine thymus and activation‐regulated chemokine (TARC/CCL17) concentrations correlate with disease severity and therapeutic responses in dogs with atopic dermatitis

open access: yesVeterinary Dermatology, Volume 31, Issue 6, Page 446-455, December 2020., 2020
Background – Thymus and activation‐regulated chemokine (TARC/CCL17) has been implicated in the pathogenesis of canine atopic dermatitis (cAD). Serum TARC concentrations are a reliable biomarker for human atopic dermatitis; however, their potential as a biomarker for cAD has not been investigated.
Ryota Asahina   +8 more
wiley   +1 more source

Detection and Inhibition of IgE for cross‐reactive carbohydrate determinants evident in an enzyme‐linked immunosorbent assay for detection of allergen‐specific IgE in the sera of dogs and cats

open access: yesVeterinary Dermatology, Volume 31, Issue 6, Page 439-e116, December 2020., 2020
Background It has been demonstrated recently that immunoglobulin (Ig)E specific for cross‐reactive carbohydrate determinants (CCD) is present in the serum of allergen‐sensitized dogs and cats, and that these CCD‐specific antibodies might confound serological testing. Hypothesis/Objective The objective was to document the prevalence of CCD detectable in
Kenneth W. Lee   +3 more
wiley   +1 more source

Discrepancies in the bilateral intradermal test and serum tests in atopic horses

open access: yesVeterinary Dermatology, Volume 31, Issue 5, Page 390-e104, October 2020., 2020
Background – In equine atopic patients intradermal testing (IDT) and immunoglobulin (Ig)E serology are used frequently. There is little evidence regarding the reproducibility of the IDT and IgE serology in horses. Objectives – To compare the results of a simultaneously performed IDT on the left and right side of the neck in atopic horses, and to ...
Catharina M. M. van Damme   +2 more
wiley   +1 more source

Rechazo crónico mediado por anticuerpos

open access: yesRevista Colombiana de Nefrología, 2022
Contexto: el rechazo crónico mediado por anticuerpos (cABMR, chronic antibody-mediated rejection) se considera una de las principales causas de disfunción crónica del injerto. Objetivo: profundizar en la comprensión de los mecanismos que la ocasionan para diseñar tratamientos efectivos, dado que es muy poco lo que se ha avanzado en el tratamiento de ...
Jessica Pinto Ramírez   +4 more
openaire   +2 more sources

The African swine fever virus isolate Belgium 2018/1 shows high virulence in European wild boar

open access: yesTransboundary and Emerging Diseases, Volume 67, Issue 4, Page 1654-1659, July 2020., 2020
Abstract African swine fever (ASF) is one of the most important and complex viral diseases in domestic pigs and wild boar. Over the last decade, the disease has spread to several European and Asian countries and is now one of the major threats to profitable pig production worldwide. One of the more recently affected western countries is Belgium.
Jutta Pikalo   +9 more
wiley   +1 more source

Successful capture of Toxocara canis larva antigens from human serum samples

open access: yesParasites & Vectors, 2015
Background Toxocara canis is a nematode that parasitizes dogs, while humans are paratenic hosts. When humans are infected the migrating larvae damage the liver, lungs and even the nervous system.
Aarón Rodríguez-Caballero   +7 more
doaj   +1 more source

Estudio longitudinal de la respuesta de anticuerpos tras la vacunación contra el SARS-CoV-2 con la vacuna BNT162b2 de Pfizer-BioNtech

open access: yesAdvances in Laboratory Medicine, 2023
Se realizó un estudio para evaluar la inmunidad de trabajadores sanitarios y no sanitarios del área de salud de Alcoy (España), tras haber recibido tres dosis de la vacuna de Pfizer-BioNTech y analizar su relación con factores individuales.
Robles Navas Leandra J.   +5 more
doaj   +1 more source

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