Results 1 to 10 of about 75 (68)
Some of the next articles are maybe not open access.

Anticuerpos monoclonales. Aspectos básicos

open access: yesNeurología, 2011
Resumen: Introducción: Los anticuerpos monoclonales son una poderosa herramienta para el diagnóstico de laboratorio y un instrumento cada vez más utilizado en el tratamiento de diversas enfermedades. Desarrollo: El descubrimiento y caracterización de los anticuerpos tiene una larga historia, que es la de la propia inmunología.
exaly   +3 more sources

Anticuerpos monoclonales en cáncer infantil.

open access: yesThe Ecuador Journal of Medicine, 2022
Resumen Introducción: El cáncer infantil es poco frecuente, se presenta en diversas edades, etnias y posición económica, su tratamiento en la mayoría de ellos tiene una alta toxicidad por lo que se analizarán los anticuerpos monoclonales como terapia alternativa, los mismos que han sido estudiados desde 1974 por Jerne, Köhler y Milstein, en la ...
Mayra Viviana Jaramillo Toapanta   +1 more
openaire   +1 more source

Cytokine transcriptome profiling in acute experimental canine atopic dermatitis skin lesions after IL‐31 inhibition with lokivetmab

open access: yesVeterinary Dermatology, Volume 34, Issue 4, Page 327-338, August 2023., 2023
Background – The caninised monoclonal antibody lokivetmab (LKV), directed at interleukin (IL)‐31, is very effective at controlling pruritus in most dogs with atopic dermatitis (AD). However, evidence exists that IL‐31 is not required for the induction of acute allergic skin inflammation, which might explain why this treatment is less efficacious in ...
Chie Tamamoto‐Mochizuki   +4 more
wiley   +1 more source

A masked, randomised clinical trial evaluating the efficacy and safety of lokivetmab compared to saline control in client‐owned dogs with allergic dermatitis

open access: yesVeterinary Dermatology, Volume 32, Issue 5, Page 477-e131, October 2021., 2021
Background – Interleukin (IL)‐31 is an important mediator in canine atopic dermatitis (cAD) and also may be dysregulated in other allergic diseases. Hypothesis/Objectives – To demonstrate the efficacy and safety of lokivetmab (canine anti‐IL‐31 monoclonal antibody) for treatment of pruritus associated with allergic dermatitis in dogs.
Leen Van Brussel   +4 more
wiley   +1 more source

Anticuerpos monoclonales

open access: yesDiagnóstico, 2021
Complejos glico-protéicos idénticos producidos y secretadas por un específico “clon o familia” de linfocitos B especializadas conocidas como células plasmáticas. Son producidas en respuesta a moléculas o micro organismos (denominados antígenos) y son reconocidas como primera línea de respuesta del sistema inmune adaptativo(1).
openaire   +1 more source

Detection and Inhibition of IgE for cross‐reactive carbohydrate determinants evident in an enzyme‐linked immunosorbent assay for detection of allergen‐specific IgE in the sera of dogs and cats

open access: yesVeterinary Dermatology, Volume 31, Issue 6, Page 439-e116, December 2020., 2020
Background It has been demonstrated recently that immunoglobulin (Ig)E specific for cross‐reactive carbohydrate determinants (CCD) is present in the serum of allergen‐sensitized dogs and cats, and that these CCD‐specific antibodies might confound serological testing. Hypothesis/Objective The objective was to document the prevalence of CCD detectable in
Kenneth W. Lee   +3 more
wiley   +1 more source

Discrepancies in the bilateral intradermal test and serum tests in atopic horses

open access: yesVeterinary Dermatology, Volume 31, Issue 5, Page 390-e104, October 2020., 2020
Background – In equine atopic patients intradermal testing (IDT) and immunoglobulin (Ig)E serology are used frequently. There is little evidence regarding the reproducibility of the IDT and IgE serology in horses. Objectives – To compare the results of a simultaneously performed IDT on the left and right side of the neck in atopic horses, and to ...
Catharina M. M. van Damme   +2 more
wiley   +1 more source

Endothelium capture‐based liver segment imaging using vascular endothelial growth factor receptor 2 in preclinical ex vivo models

open access: yesBJS Open, Volume 4, Issue 2, Page 332-341, April 2020., 2020
Imaging of liver segments provides substantial information for surgeons when performing liver resection. The anti‐vascular endothelial growth factor receptor (VEGFR) 2 antibody ramucirumab conjugated with near‐infrared dye could visualize selected liver segments using an endothelial capture‐based approach in an isolated perfusion liver model.
D. Kyuno   +4 more
wiley   +1 more source

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