Results 1 to 10 of about 75 (68)
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Anticuerpos monoclonales. Aspectos básicos
Resumen: Introducción: Los anticuerpos monoclonales son una poderosa herramienta para el diagnóstico de laboratorio y un instrumento cada vez más utilizado en el tratamiento de diversas enfermedades. Desarrollo: El descubrimiento y caracterización de los anticuerpos tiene una larga historia, que es la de la propia inmunología.
exaly +3 more sources
Anticuerpos monoclonales en cáncer infantil.
Resumen Introducción: El cáncer infantil es poco frecuente, se presenta en diversas edades, etnias y posición económica, su tratamiento en la mayoría de ellos tiene una alta toxicidad por lo que se analizarán los anticuerpos monoclonales como terapia alternativa, los mismos que han sido estudiados desde 1974 por Jerne, Köhler y Milstein, en la ...
Mayra Viviana Jaramillo Toapanta +1 more
openaire +1 more source
Background – The caninised monoclonal antibody lokivetmab (LKV), directed at interleukin (IL)‐31, is very effective at controlling pruritus in most dogs with atopic dermatitis (AD). However, evidence exists that IL‐31 is not required for the induction of acute allergic skin inflammation, which might explain why this treatment is less efficacious in ...
Chie Tamamoto‐Mochizuki +4 more
wiley +1 more source
Background – Interleukin (IL)‐31 is an important mediator in canine atopic dermatitis (cAD) and also may be dysregulated in other allergic diseases. Hypothesis/Objectives – To demonstrate the efficacy and safety of lokivetmab (canine anti‐IL‐31 monoclonal antibody) for treatment of pruritus associated with allergic dermatitis in dogs.
Leen Van Brussel +4 more
wiley +1 more source
Complejos glico-protéicos idénticos producidos y secretadas por un específico “clon o familia” de linfocitos B especializadas conocidas como células plasmáticas. Son producidas en respuesta a moléculas o micro organismos (denominados antígenos) y son reconocidas como primera línea de respuesta del sistema inmune adaptativo(1).
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Background It has been demonstrated recently that immunoglobulin (Ig)E specific for cross‐reactive carbohydrate determinants (CCD) is present in the serum of allergen‐sensitized dogs and cats, and that these CCD‐specific antibodies might confound serological testing. Hypothesis/Objective The objective was to document the prevalence of CCD detectable in
Kenneth W. Lee +3 more
wiley +1 more source
Discrepancies in the bilateral intradermal test and serum tests in atopic horses
Background – In equine atopic patients intradermal testing (IDT) and immunoglobulin (Ig)E serology are used frequently. There is little evidence regarding the reproducibility of the IDT and IgE serology in horses. Objectives – To compare the results of a simultaneously performed IDT on the left and right side of the neck in atopic horses, and to ...
Catharina M. M. van Damme +2 more
wiley +1 more source
Imaging of liver segments provides substantial information for surgeons when performing liver resection. The anti‐vascular endothelial growth factor receptor (VEGFR) 2 antibody ramucirumab conjugated with near‐infrared dye could visualize selected liver segments using an endothelial capture‐based approach in an isolated perfusion liver model.
D. Kyuno +4 more
wiley +1 more source

