Results 91 to 100 of about 276,787 (297)

Association of Antidepressant Use With Adverse Health Outcomes: A Systematic Umbrella Review.

open access: yesJAMA psychiatry, 2019
Importance Antidepressant use is increasing worldwide. Yet, contrasting evidence on the safety of antidepressants is available from meta-analyses, and the credibility of these findings has not been quantified.
E. Dragioti   +16 more
semanticscholar   +1 more source

A Comprehensive Overview of Cellulose and Its Derivatives: Structural Features and Emerging Applications

open access: yesJournal of Applied Polymer Science, EarlyView.
From plant cell wall architecture to advanced materials: cellulose and its derivatives as versatile building blocks. ABSTRACT Growing interest in cellulose as a versatile material has driven extensive research into its chemical architecture, processing methods, mechanical properties, aggregation behavior, and structural organization, both in solution ...
Denys M. M. Fertonani   +7 more
wiley   +1 more source

S-allyl Cysteine, a Garlic Compound, Produces an Antidepressant-Like Effect and Exhibits Antioxidant Properties in Mice [PDF]

open access: gold, 2020
Elizabeth Ruiz-Sánchez   +4 more
openalex   +1 more source

Cytokine pathways driving diverse tissue pathologies in rheumatoid arthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Rheumatoid arthritis is a complex systemic disorder characterised primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease e.g. of the lung with potentially devastating clinical consequences.
Aurelie Najm   +2 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

A synaptic locus for TrkB signaling underlying ketamine rapid antidepressant action [PDF]

open access: gold, 2021
Pei-Yi Lin   +4 more
openalex   +1 more source

Molecular and cellular mechanisms underlying the antidepressant effects of ketamine enantiomers and its metabolites

open access: yesTranslational Psychiatry, 2019
Although the robust antidepressant effects of the N-methyl-d-aspartate receptor (NMDAR) antagonist ketamine in patients with treatment-resistant depression are beyond doubt, the precise molecular and cellular mechanisms underlying its antidepressant ...
Chun Yang   +3 more
semanticscholar   +1 more source

Novel Sulfonylhydrazones With Sulfonate Ester Framework: Promising Dual Inhibitors of AChE and hCAs

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions of individuals worldwide. Treatment strategies for AD vary depending on cognitive and behavioral symptoms, with cholinergic replacement therapy using acetylcholinesterase (AChE) inhibitors being one of the primary approaches.
Cansu Öztürk   +3 more
wiley   +1 more source

Food-derived protein hydrolysates and peptides: anxiolytic and antidepressant activities, characteristics, and mechanisms

open access: yesFood Science and Human Wellness
Globally, the prevalence of anxiety and depression has reached epidemic proportions. Food-derived protein hydrolysates and peptides delivered through dietary supplementation can avoid the negative risks associated with traditional pharmaceuticals while ...
Wenhui Li   +5 more
doaj   +1 more source

Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022: A repeated cross‐sectional study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Analgesic medicines are an important component of pain management, with different medicines carrying different risks and benefits. The aim of this study was to examine trends in analgesic prescribing in Ireland and England between 2014 and 2022. Methods Monthly data on medicines prescribed and dispensed in primary care were used. For Ireland, data
Molly Mattsson   +8 more
wiley   +1 more source

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