Results 31 to 40 of about 276,787 (297)

Antidepressant Medications and Weight Change: A Narrative Review

open access: yesObesity, 2020
Antidepressant medications are the first‐line treatment option for moderate to severe major depressive disorder. However, most antidepressants have numerous documented adverse events, including cardiometabolic effects and weight gain, which are major ...
H. Gill   +13 more
semanticscholar   +1 more source

Serotonin antidepressants and atrial fibrillation burden from cardiac implantable electronic devices

open access: yesJournal of Arrhythmia, 2023
Objective Depression and anxiety show a bidirectional relationship with atrial fibrillation (AF). Antidepressant use is associated with a reduction in the incidence of AF.
Youlin Koh   +4 more
doaj   +1 more source

Therapeutic characteristics of patients followed for bipolar disorder with rapid cycles: Study on a Tunisian population

open access: yesEuropean Psychiatry, 2022
Introduction Bipolar disorder is a frequent and particularly severe psychiatric pathology that causes significant morbidity and mortality. The rapid cycling forms are more severe in terms of their expression, evolutionary course, therapeutic responses ...
M. Karoui   +4 more
doaj   +1 more source

Rapid‐acting antidepressant ketamine, its metabolites and other candidates: A historical overview and future perspective

open access: yesPsychiatry and Clinical Neurosciences, 2019
Major depressive disorder (MDD) is one of the most disabling psychiatric disorders. Approximately one‐third of the patients with MDD are treatment resistant to the current antidepressants.
K. Hashimoto
semanticscholar   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Soluble Epoxide Hydrolase Inhibitor: A Novel Potential Therapeutic or Prophylactic Drug for Psychiatric Disorders

open access: yesFrontiers in Pharmacology, 2019
Psychiatric disorders, including depression and schizophrenia, affect millions of individuals worldwide. However, the precise neurobiology of psychiatric disorders remains unclear. Accumulating evidence suggests that various inflammatory processes play a
Qian Ren, Qian Ren
doaj   +1 more source

Treatment of the depressive patients at clinical high-risk for psychosis

open access: yesEuropean Psychiatry, 2022
Introduction At present, there is no universally approach to treating patients at clinical high-risk for psychosis (CHR) without comorbid mental disorders.
M. Omelchenko
doaj   +1 more source

Modulation of the antidepressant effects of ketamine by the mTORC1 inhibitor rapamycin

open access: yesNeuropsychopharmacology, 2020
Twenty-four hours after administration, ketamine exerts rapid and robust antidepressant effects that are thought to be mediated by activation of the mechanistic target of rapamycin complex 1 (mTORC1).
C. Abdallah   +13 more
semanticscholar   +1 more source

Prophylactic Management of Vestibular Migraine: A Systematic Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Vestibular migraine (VM) is a neurological disorder characterized by episodic vertigo in patients with migraine, contributing to substantial functional impairment. Although VM is relatively common, a consensus on effective prophylactic treatments is lacking.
Hussain Ali Almohammed   +11 more
wiley   +1 more source

Functional connectivity of brain structures correlates with treatment outcome in Major Depressive Disorder

open access: yesFrontiers in Psychiatry, 2011
Identifying biosignatures to assess the probability of response to an antidepressant for patients with Major Depressive Disorder (MDD) is critically needed. Functional connectivity MRI (fcMRI) offers the promise to provide such a measure.
F. Andrew eKozel   +10 more
doaj   +1 more source

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