Results 41 to 50 of about 121,953 (266)

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Ectopic pregnancy, its potential links to dementia risk and interactions with depression: insights from a nationwide cohort study

Frontiers in Psychiatry
BackgroundDementia poses a growing global mental health impact, with variations in prevalence by gender, possibly influenced by reproductive factors. Ectopic pregnancy (EP), known for its association with cardiovascular diseases and depression, which are
Chia-Yi Yao, Chi-Hsiang Chung, Chi-Hsiang Chung, Chi-Hsiang Chung, Wu-Chien Chien, Wu-Chien Chien, Wu-Chien Chien, Wu-Chien Chien, Sung-Tao Li, Siou-Ting Lee, Siou-Ting Lee, Chih-Chung Huang, Chuan-Chi Yang, Chuan-Chi Yang, Nian-Sheng Tzeng, Nian-Sheng Tzeng   +15 more
doaj   +1 more source

Acneiform eruption associated with the use of vortioxetine

Psychiatry and Clinical Psychopharmacology, 2019
Acneiform is used to describe eruptions that resemble acne vulgaris, but are not aetiologically similar. A number of drugs that can be responsible for acneiform eruptions exist.
Rukiye Ay, Ozgur Aytas
doaj   +1 more source

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

Arthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah, Cherish Wilson, Christine Hariz, Christie M. Bartels, Shanthini Kasturi, Wambui Machua, Amy Bennett, Kate Chiseri, Allison Plitman, Starla Hairston Blanks, April Jorge, Patti Katz, Jinoos Yazdany, Shivani Garg   +13 more
wiley   +1 more source

The utility of PET imaging in depression

Frontiers in Psychiatry
This educational review article aims to discuss growing evidence from PET studies in the diagnosis and treatment of depression. PET has been used in depression to explore the neurotransmitters involved, the alterations in neuroreceptors, non ...
Shashi B. Singh, Atit Tiwari, Maanya R. Katta, Riju Kafle, Cyrus Ayubcha, Cyrus Ayubcha, Krishna H. Patel, Yash Bhattarai, Thomas J. Werner, Abass Alavi, Mona-Elisabeth Revheim, Mona-Elisabeth Revheim   +11 more
doaj   +1 more source

Alopecia associated with agomelatine use: a case report

Psychiatry and Clinical Psychopharmacology, 2018
Drug-induced alopecia, characterized by non-scarring hair loss of scalp and body, is a rare side effect of psychotropic drugs. It has previously been reported with the different antidepressant medications, but has not been described with agomelatine ...
Ibrahim Gundogmus, Mustafa Ispir, Abdulkadir Karagoz, Ayhan Algul, Servet Ebrinc   +4 more
doaj   +1 more source

Water‐Compatible SuFEx‐Active Diazonium Linchpin Platform for Rapid Modular Diversification and On‐DNA Functionalization

Advanced Functional Materials, EarlyView.
Sulfur fluoride exchange (SuFEx) is a powerful click platform, yet water‐compatible multifunctional linchpins remain elusive. Here, we report decagram‐scalable diazonium linchpins that enable rapid Pd‐catalyzed diversification and direct, catalyst‐free on‐DNA ligation in aqueous media.
Seok Ju Hong, Dong Hyeon Kim, Yujin Lim, Yongseok Kwon, Sangkyu Lee, Han Yong Bae   +5 more
wiley   +1 more source

Surge in antidepressant usage among adolescents and young adults during the COVID-19 pandemic: insights from an interrupted time series analysis

Epidemiology and Psychiatric Sciences
Background Depressive disorders are a major public health issue in Western societies, particularly among adolescents, young adults and women. The COVID-19 pandemic has exacerbated mental health challenges, increasing depression and anxiety symptoms ...
Zeno Di Valerio, Daniela Fortuna, Marco Montalti, Lucia Alberghini, Anna Caterina Leucci, Alessio Saponaro, Elisa Sangiorgi, Elena Berti, Maurizia Rolli, Dario Tedesco   +9 more
doaj   +1 more source

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source