Results 41 to 50 of about 174,749 (313)

Design, Synthesis, and In Vivo and In Silico Evaluation of Coumarin Derivatives with Potential Antidepressant Effects

open access: yesMolecules, 2021
In this study, a series of coumarin derivatives were designed and synthesized, their structures were characterized using nuclear magnetic resonance (NMR) and high-resolution mass spectrometry (HRMS) testing methods. In the pharmacological experiment, two
Xuekun Wang   +4 more
doaj   +1 more source

Why antidepressants are not antidepressants

open access: yesMental Health Clinician, 2012
This statement begins Dr. Ghaemi’s review of “Why antidepressants are not antidepressants: STEP-BD, STAR*D, and the return of neurotic depression“ published in Bipolar Disorders in 2008. The article addresses a segment of the controversial evidence to be presented as part of Annual Meeting recertification programming surrounding the use of ...
openaire   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Ectopic pregnancy, its potential links to dementia risk and interactions with depression: insights from a nationwide cohort study

open access: yesFrontiers in Psychiatry
BackgroundDementia poses a growing global mental health impact, with variations in prevalence by gender, possibly influenced by reproductive factors. Ectopic pregnancy (EP), known for its association with cardiovascular diseases and depression, which are
Chia-Yi Yao   +15 more
doaj   +1 more source

Acneiform eruption associated with the use of vortioxetine

open access: yesPsychiatry and Clinical Psychopharmacology, 2019
Acneiform is used to describe eruptions that resemble acne vulgaris, but are not aetiologically similar. A number of drugs that can be responsible for acneiform eruptions exist.
Rukiye Ay, Ozgur Aytas
doaj   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli   +13 more
wiley   +1 more source

The utility of PET imaging in depression

open access: yesFrontiers in Psychiatry
This educational review article aims to discuss growing evidence from PET studies in the diagnosis and treatment of depression. PET has been used in depression to explore the neurotransmitters involved, the alterations in neuroreceptors, non ...
Shashi B. Singh   +11 more
doaj   +1 more source

Alopecia associated with agomelatine use: a case report

open access: yesPsychiatry and Clinical Psychopharmacology, 2018
Drug-induced alopecia, characterized by non-scarring hair loss of scalp and body, is a rare side effect of psychotropic drugs. It has previously been reported with the different antidepressant medications, but has not been described with agomelatine ...
Ibrahim Gundogmus   +4 more
doaj   +1 more source

The antidepressant debate [PDF]

open access: yesBritish Journal of Psychiatry, 2002
There has been an extensive debate recently in the North American medical literature and general press concerning the efficacy of antidepressant drugs. Little of this has reached the European press.
openaire   +2 more sources

Antidepressant-associated sexual dysfunction: impact, effects, and treatment

open access: yes, 2010
Agnes Higgins, Michael Nash, Aileen M LynchSchool of Nursing and Midwifery Studies, Trinity College Dublin, Dublin, IrelandAbstract: Sexual dysfunction is a common side effect of antidepressants and can have significant impact on the person’s ...
LYNCH, AILEEN   +5 more
core   +1 more source

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