Results 31 to 40 of about 174,749 (313)

Treatment-Resistant Depression that Recovered after Toxoplasma Gondii Treatment: A Case Report

open access: yesPsychiatry and Behavioral Sciences, 2020
Toxoplasma Gondii is an obligate intracellular parasite which may infect all nucleated cells. Studies conducted in adult patients show that toxoplasmosis may be related to psychiatric diseases and there is a correlation between Toxoplasma Gondii and ...
Yekta Ozkan   +4 more
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

Agomelatin's Effect on Parkinson Disease Model on Rats

open access: yesJournal of Behçet Uz Children's Hospital, 2019
INTRODUCTION: Parkinson disease is one of the most common neurodegenerative disorders. This disease still have no exact cure. Agomelatin is the synthetic analog of melatonin hormone that is synthesized in pineal gland and then released from there ...
Pınar Ayvat   +2 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

Association of inflammation cytokines with cognitive function in first-episode major depressive disorder

open access: yesFrontiers in Psychiatry
ObjectiveAbnormal cognitive functioning is a core symptom of Major Depressive Disorder (MDD) and is strongly correlated with MDD prognosis. Current studies suggest that the occurrence of MDD may be related to oxidative stress-induced inflammation ...
Yan Qing Xi   +22 more
doaj   +1 more source

3D-ALMOND-QSAR Models to Predict the Antidepressant Effect of Some Natural Compounds

open access: yesPharmaceutics, 2021
The current treatment of depression involves antidepressant synthetic drugs that have a variety of side effects. In searching for alternatives, natural compounds could represent a solution, as many studies reported that such compounds modulate the ...
Speranta Avram   +5 more
doaj   +1 more source

Antidepressants in adolescence

open access: yesAustralian Prescriber, 2022
In adolescence, antidepressants are second-line treatment options after psychological therapy for anxiety and obsessive compulsive disorder. They may be first- or second-line options for severe cases of major depressive disorder. The response to antidepressant treatment is generally good for anxiety and obsessive compulsive disorder, but is less ...
openaire   +2 more sources

Utilization of antidepressants in Taiwan: a nationwide population-based survey from 2000 to 2009

open access: yes, 2014
Objective This study examined trends in antidepressant utilization in Taiwan between 2000 and 2009. Methods We collected data from the National Health Insurance Research Database of all incident antidepressant use. We described the incidence, prevalence,
賴美淑   +1 more
core   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma   +16 more
wiley   +1 more source

Emulating a randomized clinical trial with real-world data to evaluate the effect of antidepressant use in PTSD patients with high suicide risk

open access: yesFrontiers in Psychiatry
IntroductionPost-Traumatic Stress Disorder (PTSD) entails behavioral changes with increased risk of suicide, and there is no consensus on the preferred antidepressants for treatment of those PTSD patients who are at elevated risk for suicide.MethodsWe ...
Oshin Miranda   +10 more
doaj   +1 more source

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