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Antidepressants in bipolar depression: an enduring controversy
The proper place and the optimal use of antidepressants in treating bipolar depression continues to be an area of great interest and greater controversy with passionate opinions more common than good studies. Even the handful of meta-analyses in the area
Michael J. Gitlin
doaj +2 more sources
Antidepressants for the treatment of depression in people with cancer.
BACKGROUND Major depression and other depressive conditions are common in people with cancer. These conditions are not easily detectable in clinical practice, due to the overlap between medical and psychiatric symptoms, as described by diagnostic manuals
Giovanni Vita+4 more
semanticscholar +1 more source
Sustained effects of rapidly-acting antidepressants require BDNF-dependent MeCP2 phosphorylation
The rapidly acting antidepressants ketamine and scopolamine exert behavioral effects that can last from several days to more than a week in some patients.
Ji-Woon Kim+6 more
semanticscholar +1 more source
Depression, antidepressants and fall risk: therapeutic dilemmas—a clinical review
To summarize the existing knowledge on fall risk associated with antidepressant use in older adults, including the underlying pathophysiology, and assist clinicians in (de-) prescribing antidepressants.
E. V. van Poelgeest+3 more
semanticscholar +1 more source
Few studies have delineated the real-world, long-term trends of prescription patterns of antidepressants for patients with major depressive disorder (MDD).
Yan Luo+4 more
semanticscholar +1 more source
Antidepressants promote the spread of extracellular antibiotic resistance genes via transformation
The development of antibiotic resistance as an unavoidable consequence of the application of antimicrobials is a significant concern for human health. Antidepressants are being increasingly consumed globally.
Ji Lu+3 more
doaj +1 more source
BackgroundPost-stroke depression (PSD) is a common psychiatric complication of mental disorders after stroke. Acupuncture for PSD is effective and has few adverse effects. As a classical complementary and alternative therapy, acupuncture is often used in
Chun Li+4 more
doaj +1 more source
Background: Incomplete hippocampal inversion (IHI), also called malrotation, is a frequent atypical anatomical pattern of the hippocampus. Because of the crucial implication of the hippocampus in Major Depressive Disorder (MDD) and the neurodevelopmental
Romain Colle+9 more
doaj +1 more source
Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence [PDF]
Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of its attention to this problematic and many drugs have been developed and are currently ...
Berrocoso Domínguez, Esther María+4 more
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Nefazodone in psychotic unipolar and bipolar depression: A retrospective chart analysis and open prospective study on its efficacy and safety versus combined treatment with amitriptyline and haloperidol [PDF]
Although atypical antipsychotics are on the rise, traditional treatment of psychotic (or delusional) depression mostly includes the addition of classical antipsychotics to antidepressants. As there are only few data supporting this approach compared with
Born, Christoph+4 more
core +1 more source