Results 11 to 20 of about 286,539 (338)

Antidepressants in bipolar depression: an enduring controversy

International Journal of Bipolar Disorders, 2018
The proper place and the optimal use of antidepressants in treating bipolar depression continues to be an area of great interest and greater controversy with passionate opinions more common than good studies. Even the handful of meta-analyses in the area
Michael J. Gitlin
doaj   +2 more sources

Pharmacogenetics of antidepressants [PDF]

Frontiers in Pharmacology, 2011
Up to 60% of depressed patients do not respond completely to antidepressants (AD) and up to 30% do not respond at all. Genetic factors contribute for about 50% of the AD response. During the recent years the possible influence of a set of candidate genes
Concetta eCrisafulli, Chiara eFabbri, Stefano ePorcelli, Antonio eDrago, Edoardo eSpina, Diana eDe Ronchi, Alessandro eSerretti   +6 more
doaj   +6 more sources

Antidepressants for the treatment of depression in people with cancer.

Cochrane Database of Systematic Reviews, 2023
BACKGROUND Major depression and other depressive conditions are common in people with cancer. These conditions are not easily detectable in clinical practice, due to the overlap between medical and psychiatric symptoms, as described by diagnostic manuals
Giovanni Vita, Beatrice Compri, F. Matcham, C. Barbui, G. Ostuzzi   +4 more
semanticscholar   +1 more source

Antidepressants fluoxetine and amitriptyline induce alterations in intestinal microbiota and gut microbiome function in rats exposed to chronic unpredictable mild stress

Translational Psychiatry, 2021
Antidepressant medications are known to modulate the central nervous system, and gut microbiota can play a role in depression via microbiota–gut–brain axis.
Weijie Zhang, Wan Qu, Hua Wang, He Yan
semanticscholar   +1 more source

Depression and Pain: Use of Antidepressants

Current Neuropharmacology, 2021
Background: Emotional disorders are common comorbid affectations that exacerbate the severity and persistence of chronic pain. Specifically, depressive symptoms can lead to an excessive duration and intensity of pain.
J. A. Sánchez-Salcedo, Maribel Maetizi Estevez Cabrera, Tania Molina-Jiménez, J. Cortes-Altamirano, A. Alfaro-Rodríguez, H. Bonilla-Jaime   +5 more
semanticscholar   +1 more source

Sustained effects of rapidly-acting antidepressants require BDNF-dependent MeCP2 phosphorylation

Nature Neuroscience, 2021
The rapidly acting antidepressants ketamine and scopolamine exert behavioral effects that can last from several days to more than a week in some patients.
Ji-Woon Kim, Anita E. Autry, E. Na, M. Adachi, C. Björkholm, E. Kavalali, L. Monteggia   +6 more
semanticscholar   +1 more source

Depression, antidepressants and fall risk: therapeutic dilemmas—a clinical review

European Geriatric Medicine, 2021
To summarize the existing knowledge on fall risk associated with antidepressant use in older adults, including the underlying pathophysiology, and assist clinicians in (de-) prescribing antidepressants.
E. V. van Poelgeest, A. Pronk, D. Rhebergen, N. van der Velde   +3 more
semanticscholar   +1 more source

Safety of 80 antidepressants, antipsychotics, anti‐attention‐deficit/hyperactivity medications and mood stabilizers in children and adolescents with psychiatric disorders: a large scale systematic meta‐review of 78 adverse effects

World Psychiatry, 2020
Mental disorders frequently begin in childhood or adolescence. Psychotropic medications have various indications for the treatment of mental disorders in this age group and are used not infrequently off‐label.
M. Solmi, M. Fornaro, E. Ostinelli, Caroline Zangani, Giovanni Croatto, Francesco Monaco, Damir Krinitski, P. Fusar-Poli, C. Correll   +8 more
semanticscholar   +1 more source

National Prescription Patterns of Antidepressants in the Treatment of Adults With Major Depression in the US Between 1996 and 2015: A Population Representative Survey Based Analysis

Frontiers in Psychiatry, 2020
Few studies have delineated the real-world, long-term trends of prescription patterns of antidepressants for patients with major depressive disorder (MDD).
Yan Luo, Yuki Kataoka, E. Ostinelli, A. Cipriani, T. Furukawa   +4 more
semanticscholar   +1 more source

Hippocampal volume predicts antidepressant efficacy in depressed patients without incomplete hippocampal inversion

NeuroImage: Clinical, 2016
Background: Incomplete hippocampal inversion (IHI), also called malrotation, is a frequent atypical anatomical pattern of the hippocampus. Because of the crucial implication of the hippocampus in Major Depressive Disorder (MDD) and the neurodevelopmental
Romain Colle, Claire Cury, Marie Chupin, Eric Deflesselle, Patrick Hardy, Ghaidaa Nasser, Bruno Falissard, Denis Ducreux, Olivier Colliot, Emmanuelle Corruble   +9 more
doaj   +1 more source