Results 21 to 30 of about 191,413 (246)

A magic pill? A qualitative analysis of patients’ views on the role of antidepressant therapy in inflammatory bowel disease (IBD)

BMC Gastroenterology, 2012
Background Studies with healthy volunteers have demonstrated that antidepressants can improve immunoregulatory activity and thus they may have a potential to positively impact the disease course in inflammatory bowel disease (IBD), a chronic and ...
Mikocka-Walus Antonina A, Gordon Andrea L, Stewart Benjamin J, Andrews Jane M   +3 more
doaj   +1 more source

Non-Adherence to Antidepressant Treatment and Related Factors in a Region of Spain: A Population-Based Registry Study

Pharmaceutics, 2022
Antidepressants are a commonly prescribed psychotropic medication, and their use has increased in recent years. Medication non-adherence in patients with mental disorders is associated with worse health outcomes.
M. Aránzazu Pedrosa-Naudín, Eduardo Gutiérrez-Abejón, Francisco Herrera-Gómez, Diego Fernández-Lázaro, F. Javier Álvarez   +4 more
doaj   +1 more source

Antidepressants vs. Placebo for the Treatment of Functional Gastrointestinal Disorders in Adults: A Systematic Review and Meta-Analysis

Frontiers in Psychiatry, 2018
Objective: To integrate high-quality evidence of the efficacy of antidepressants across different subtypes of functional gastrointestinal disorders (FGIDs).Methods: The Medline, PsycINFO, EMBASE, the Cochrane Library, and Chinese local database were ...
Nana Xiong, Yanping Duan, Jing Wei, Ricarda Mewes, Rainer Leonhart   +4 more
doaj   +1 more source

Antidepressant Screening Demonstrated Non-Monotonic Responses to Amitriptyline, Amoxapine and Sertraline in Locomotor Activity Assay in Larval Zebrafish

Cells, 2021
Antidepressants are well-known drugs to treat depression and major depressive disorder for humans. However, the misuse and abuse of antidepressants keep increasing with several side effects reported.
Michael Edbert Suryanto, Gilbert Audira, Boontida Uapipatanakul, Akhlaq Hussain, Ferry Saputra, Petrus Siregar, Kelvin H.-C. Chen, Chung-Der Hsiao   +7 more
doaj   +1 more source

Antidepressants affect gut microbiota and Ruminococcus flavefaciens is able to abolish their effects on depressive-like behavior

Translational Psychiatry, 2019
Accumulating evidence demonstrates that the gut microbiota affects brain function and behavior, including depressive behavior. Antidepressants are the main drugs used for treatment of depression. We hypothesized that antidepressant treatment could modify
I. Lukic, Dmitriy Getselter, O. Ziv, O. Oron, E. Reuveni, O. Koren, E. Elliott   +6 more
semanticscholar   +1 more source

Antidepressants have Anti-inflammatory Effects that may be Relevant to Dermatology: A Systematic Review

Acta Dermato-Venereologica, 2017
There is increasing evidence of clinically relevant anti-inflammatory effects of monoaminergic antidepressants. PubMed and Ovid databases were searched systematically for the use and efficacy of antidepressants in association with 5 common inflammatory ...
Shirin Eskeland, Jon Anders Halvorsen, Lars Tanum   +2 more
doaj   +1 more source

Molecular mechanisms of rapid-acting antidepressants: New perspectives for developing antidepressants

Pharmacological Research, 2023
Major depressive disorder (MDD) is a chronic relapsing psychiatric disorder. Conventional antidepressants usually require several weeks of continuous administration to exert clinically significant therapeutic effects, while about two-thirds of the ...
Tao Chen, Ling Cheng, Jingwen Ma, Jiyuan Yuan, Chao Pi, Linjin Xiong, Jinglin Chen, Huiyang Liu, Jia Tang, Yueting Zhong, Xiaomei Zhang, Zerong Liu, Ying Zuo, Hongping Shen, Yumeng Wei, Ling Zhao   +15 more
doaj   +1 more source

Effects of Antidepressants on Sleep

Current Psychiatry Reports, 2017
Purpose of ReviewThe aim of this review article was to summarize recent publications on effects of antidepressants on sleep and to show that these effects not only depend on the kind of antidepressant drugs but are also related to the dose, the time of ...
A. Wichniak, A. Wierzbicka, Małgorzata Walęcka, W. Jernajczyk   +3 more
semanticscholar   +1 more source

‘Never change a winning team’: GPs’ perspectives on discontinuation of long-term antidepressants

Scandinavian Journal of Primary Health Care, 2021
Background Long-term antidepressant use, much longer than recommended by guidelines, can harm patients and generate unnecessary costs. Most antidepressants are prescribed by general practitioners (GPs) but it remains unclear why they do not discontinue ...
Van Leeuwen Ellen, Sibyl Anthierens, Mieke L. van Driel, An De Sutter, Evelien van den Branden, Thierry Christiaens   +5 more
doaj   +1 more source

Understanding Side Effects of Antidepressants: Large-scale Longitudinal Study on Social Media Data

JMIR Mental Health, 2021
BackgroundAntidepressants are known to show heterogeneous effects across individuals and conditions, posing challenges to understanding their efficacy in mental health treatment.
Saha, Koustuv, Torous, John, Kiciman, Emre, De Choudhury, Munmun   +3 more
doaj   +1 more source