Results 81 to 90 of about 168,234 (309)

Therapeutic Prospects of Ketamine for Cataplexy in Narcolepsy Type 1: Evidence from a Human Case and a Murine Model

open access: yesAnnals of Neurology, EarlyView.
Narcolepsy type 1 is characterized by cataplexy, for which current treatments targeting monoaminergic, histaminergic, and GABAergic pathways may be ineffective or poorly tolerated. We report the case of a 34‐year‐old man with narcolepsy type 1, intolerant to standard therapies, who experienced marked and sustained cataplexy reduction with morning ...
Francois Ricordeau   +8 more
wiley   +1 more source

Risk of manic switch with antidepressants use in patients with bipolar disorder in a Nigerian neuropsychiatric hospital

open access: yesSouth African Journal of Psychiatry, 2018
Background: Depressive disorders are common among those with bipolar affective disorder (BAD) and may necessitate the use of antidepressants. This has been suggested to precipitate manic episodes in some patients.
Ayodele L. Fela-Thomas   +2 more
doaj   +1 more source

Envolvimento do sistema monoaminérgico no efeito antidepressivo do extrato das folhas de Schinus Molle L. em camundongos [PDF]

open access: yes, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.Schinus molle L. (Anacardiaceae), among other uses, is popularly employed for the treatment of depression.
Machado, Daniele Guilhermano
core  

CuO‐CuAl2O4 Catalyst for Synthesis of 1‐Methylindole by Alcohol Amine Method

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Cu‐based catalysts used for the vapor‐phase synthesis of 1‐methylindole from N‐methylaniline and ethylene glycol are prone to Cu sintering and deactivation under the reaction conditions. In this work, CuO‐CuAl2O4 catalysts were prepared by a coprecipitation method and applied to the synthesis of 1‐methylindole via alcohol amine route.
Qian Yue   +3 more
wiley   +1 more source

We can manage depression better with technology [PDF]

open access: yes, 2014
Provides a summary of the evidence for internet-delivered cognitive behaviour therapy, and looks at the three RACGP Handbook of Non-Drug Intervention (HANDI) recommendations for non-drug treatments for depression and arranged for the developers to ...
Gavin Andrews
core  

Loss of Reduction and Clavicle Fractures Commonly Occur in Patients Undergoing Acromioclavicular Joint Reconstruction and Female Sex Is Associated With Higher Fracture Risk

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To use a large, multi‐institutional database to characterize the outcomes and complication profile after primary acromioclavicular (AC) joint reconstruction and to evaluate potential sex‐related differences in outcomes and complications. Methods The TriNetX national database was queried for patients undergoing AC joint reconstruction between ...
Scott Fong   +10 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

Unravelling the efficacy of antidepressants as analgesics

open access: yes, 2016
Background: Chronic pain is a large and growing public health concern in Australia. Chronic pain is generally associated with physical, psychological, social and cultural risk factors.
Janakiraman, Raguraman   +2 more
core  

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm   +2 more
wiley   +1 more source

Augmentation with antidepressants in schizophrenia treatment: benefit or risk

open access: yes, 2015
Ye-Meng Mao, Ming-Dao Zhang Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, World Health Organization Collaborating Center for Research and Training in Mental Health, Shanghai, People’s Republic of China ...
Mao YM, Zhang MD
core  

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