Results 11 to 20 of about 5,762 (194)
Ferulic acid as a therapeutic agent in depression: Evidence from preclinical studies
CNS Neuroscience &Therapeutics, Volume 29, Issue 9, Page 2397-2412, September 2023., 2023 Abstract Depression is a common but severe mood disorder with a very high prevalence across the general population. Depression is of global concern and poses a threat to human physical and mental health. Ferulic acid (FA) is a natural active ingredient that has antioxidative, anti‐inflammatory, and free radical scavenging properties.
Xiaoyu Dong, Dongxue Zhao
wiley +1 more source
iMeta, Volume 2, Issue 3, August 2023., 2023 We successfully isolated Maca‐EVs using ultracentrifugation and tested its antidepressant effects in the unpredictable chronic mild stress mice. Maca‐EVs increased serum serotonin (5‐HT) levels probably via the gut microbiota and metabolism modulation.
Rui Hong +14 more
wiley +1 more source
Increased risk of depression after Guillain‐Barré syndrome
Muscle &Nerve, Volume 67, Issue 6, Page 497-505, June 2023., 2023 Abstract Introduction/Aims Guillain‐Barré syndrome (GBS) is a potentially life‐threatening disorder, and some patients may develop subsequent depression related to traumatic stress or permanent loss of motor function. We determined the short‐term (0 to 2 years) and long‐term (>2 years) risk of depression after GBS.
Lotte Sahin Levison +2 more
wiley +1 more source
Novel drug developmental strategies for treatment‐resistant depression
British Journal of Pharmacology, Volume 179, Issue 6, Page 1146-1186, March 2022., 2022 Major depressive disorder is a leading cause of disability worldwide. Because conventional therapies are ineffective in many patients, novel strategies are needed to overcome treatment‐resistant depression (TRD). Limiting factors of successful drug development in the last decades were the lack of (1) knowledge of pathophysiology, (2) translational ...
Éva Borbély +5 more
wiley +1 more source
Antidepressant use and stroke or mortality risk in the elderly
European Journal of Neurology, Volume 29, Issue 2, Page 469-477, February 2022., 2022 In real‐world data of the elderly population, it was found that the risk of experiencing stroke or death in antidepressant users during and up to 1 year after exposure was higher compared to non‐users, even after adjustment for possible confounders. Abstract Background and purpose Current evidence on antidepressant‐related stroke or mortality risk is ...
Begüm Irmak Ön +7 more
wiley +1 more source
BioMed Research International, Volume 2022, Issue 1, 2022., 2022 Green synthesis of nanoparticles has emerged as an effective and environmentally friendly method. Therefore, the current investigation is based on the green synthesis of zinc oxide nanoparticles (ZnO‐NPs) using plant extract of Sanvitalia procumbens (S. procumbens) that act as a capping and reducing agent. S.
Yasir Rashid +6 more
wiley +1 more source
The limited utility of electrocardiography variables used to predict arrhythmia in psychotropic drug overdose [PDF]
, 2003 The aim of the present study was to examine the relationship between serious arrhythmias in patients with psychotropic drug overdose and electrocardiography (ECG) findings that have been suggested previously to predict this complication.Thirty-nine ...
Buckley, Nicholas A. +5 more
core +1 more source
Automatic summarization of MEDLINE citations for evidence-based medical treatment: A topic-oriented evaluation [PDF]
, 2008 As the number of electronic biomedical textual resources increases, it becomes harder for physicians to find useful answers at the point of care. Information retrieval applications provide access to databases; however, little research has been done on ...
Fiszman, Marcelo +3 more
core +1 more source
Use of antidepressants and the risk of myocardial infarction in middle-aged and older adults: A matched case-control study [PDF]
, 2016 Purpose: Antidepressants, specifically selective serotonin reuptake-inhibiting antidepressants (SSRIs), decrease platelet activation and aggregation in in vitro experiments and could therefore decrease the risk of myocardial infarction (MI).
Aarts, N. (Nikkie) +7 more
core +3 more sources
Network reconstruction of platelet metabolism identifies metabolic signature for aspirin resistance. [PDF]
, 2014 Recently there has not been a systematic, objective assessment of the metabolic capabilities of the human platelet. A manually curated, functionally tested, and validated biochemical reaction network of platelet metabolism, iAT-PLT-636, was reconstructed
Bordbar, Aarash +4 more
core +2 more sources