Lithium Augmentation in Treatment‐Resistant Depression: A Qualitative Review of the Literature
ABSTRACT Depression is the leading cause of disability worldwide, affecting people of all ages. Both pharmacological and non‐pharmacological therapies are available for its treatment. However, some patients do not respond to first‐line pharmacological interventions, referred to as treatment‐resistant depression (TRD).
Angela Acero‐González +8 more
wiley +1 more source
Correlation of antidepressive agents and the mortality of end-stage renal disease
[[abstract]]Aim:Depression is one of the most common psychological disorders in end-stage renal disease (ESRD) patients and is associated with impaired quality of life and increased mortality and rate of hospitalization.
Tsai, CJ;Loh, EW;Lin, CH;Yu, TM;Chan, CH;Lan, TH
core +1 more source
The Effect of ABCB1 Polymorphisms on the Efficacy of Antidepressants
ABSTRACT This scoping review investigates the association between ABCB1 polymorphisms and antidepressant efficacy in humans. A systematic search identified 630 records, of which 58 met the inclusion criteria, resulting in 42 unique studies (five randomised controlled trials (RCTs), two randomised studies (non‐RCTs), 30 prospective cohort studies, three
Sofie Voss Thorsen +3 more
wiley +1 more source
Depression, antidepressant use, and breast cancer incidence: results from the E3N prospective cohort
Aim Depression and antidepressant drugs may both impact breast cancer incidence, potentially in opposite directions. The few epidemiological studies attempting to disentangle their effects have been inconclusive. We aimed to assess within the same prospective cohort the association between depression, antidepressant use, and breast cancer risk, while ...
Romain Colle +7 more
wiley +1 more source
Mirtazapine versus other antidepressive agents for depression.
BACKGROUND: Mirtazapine has a unique mechanism of antidepressive action and is one of the commonly used antidepressants in clinical practice. OBJECTIVES: The aim of the present review was to assess the evidence on the efficacy and acceptability of ...
Churchill, R +25 more
core +1 more source
The Global Landscape of Neuropsychiatric Prescribing Practices of Nurses: A Scoping Review
ABSTRACT Mental healthcare service access in South Africa is currently strained due to, among others, shortages of specialised mental healthcare professionals. The National Strategic Plan for HIV, TB and STIs (2023‐2028) recommends enabling nurses to diagnose, prescribe and dispense neuropsychiatric medication for promoting mental health services.
M. Naidoo, C. J. Filmalter, W. Cordier
wiley +1 more source
The Study of Clinical Finding, Complications and Management of 24 Patients with Overused T.C.A.
The extensive use of tricyclic antidepression drugs, the approximation of the therapeutic levels of the drugs to toxic level and the availability of the drugs to depressed patients who have potentially the idea of committing suicide has made these drugs ...
Saeed Fallah +2 more
doaj
Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes +4 more
wiley +1 more source
Pharmacological Treatment of Neuropsychiatric Symptoms in Huntington's Disease: A Systematic Review
ABSTRACT Background Studies focusing on the treatment of neuropsychiatric symptoms (NPS) in Huntington's disease (HD) are scarce and show a wide variation in design, outcome measures and methodological quality. The effectiveness of pharmacological treatment of NPS in HD has not been systematically reviewed so far.
Ruben L. Andriessen +5 more
wiley +1 more source
Sertraline versus other antidepressive agents for depression.
BACKGROUND: The National Institute for Health and Clinical Excellence clinical practice guideline on the treatment of depressive disorder recommended that selective serotonin reuptake inhibitors should be the first-line option when drug therapy is ...
Churchill, Rachel C +24 more
core +1 more source

