Results 31 to 40 of about 1,565,191 (184)

Contribution of physiological dynamics in predicting major depressive disorder severity

open access: yesPsychophysiology, Volume 62, Issue 2, February 2025.
Abstract This study aimed to explore the physiological dynamics of cognitive stress in patients with Major Depressive Disorder (MDD) and design a multiparametric model for objectively measuring severity of depression. Physiological signal recordings from 40 MDD patients and 40 healthy controls were collected in a baseline stage, in a stress‐inducing ...
Esther García Pagès   +11 more
wiley   +1 more source

Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian [PDF]

open access: yes, 2005
Two new tricyclic alkaloids, polycitorols A (1) and B (2) have been isolated along with the known lepadiformine (3) from a marine ascidian of the family Polycitoridae.
Setiawan, Andi   +5 more
core  

Antiepileptic and antidepressive polypharmacy in patients with multiple sclerosis. [PDF]

open access: yes, 2015
Objective. Patients with multiple sclerosis (MS) are often suffering from neuropathic pain. Antiepileptic drugs (AEDs) and tricyclic antidepressants (TCAs) are commonly used and are susceptible to be involved in drug interactions.
Beiske, Antonie Giæver   +4 more
core   +1 more source

Use of Hemoadsorption and Continuous Venovenous Hemodialysis With Enhanced Middle Molecule Clearance in Drug‐Induced Rhabdomyolysis

open access: yesCase Reports in Critical Care, Volume 2025, Issue 1, 2025.
Drug‐induced rhabdomyolysis has become increasingly prevalent due to the rising use of medications such as statins, antidepressants, and antipsychotics. These can lead to muscle cell destruction and the release of myoglobin, potentially causing kidney damage.
Sebastian Hafner   +5 more
wiley   +1 more source

Synthesis and Transformation of Tricyclic KYNA Derivatives [PDF]

open access: yes
Kynurenic acid (KYNA) derivatives condensed with an aromatic ring (tricyclic KYNA derivatives) have been successfully synthesized, and the reactivity of these analogues has been investigated in the modified Mannich reaction resulting in new Mannich bases.
Bálint Lőrinczi   +5 more
core   +1 more source

Efficacy and safety of antidepressants for pain in older adults: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, Volume 90, Issue 12, Page 3097-3118, December 2024.
Aims In many countries, pain is the most common indication for use of antidepressants in older adults. We reviewed the evidence from randomized controlled trials on the efficacy and safety of antidepressants, compared to all alternatives for pain in older adults (aged ≥65 years).
Sujita W. Narayan   +10 more
wiley   +1 more source

Ginsenoside Rg1: A Neuroprotective Natural Dammarane‐Type Triterpenoid Saponin With Anti‐Depressive Properties

open access: yesCNS Neuroscience &Therapeutics, Volume 30, Issue 12, December 2024.
Rg1 exhibits antidepressant effects through diverse mechanisms, such as anti‐inflammation, synaptic protection, neurogenesis promotion, brain‐derived neurotrophic factor release, enhancement of astrocyte gap junction function, and regulation of hypothalamic–pituitary–adrenal axis and antioxidative stress. Experimental studies validate Rg1's efficacy in
Dong Han   +5 more
wiley   +1 more source

Oxazolidinone Antibacterial Agents. An Enantioselective Synthesis of the [6,5,5] Tricyclic Fused Oxazolidinone Ring System and Application to the Synthesis of a Rigid DuP 721 Analogue

open access: yes, 2016
Oxazolidinone Antibacterial Agents. An Enantioselective Synthesis of the [6,5,5] Tricyclic Fused Oxazolidinone Ring System and Application to the Synthesis of a Rigid DuP 721 ...
D. Mark Gleave (3038250)   +1 more
core   +1 more source

A target trial emulation comparing the antidepressant effectiveness of selective serotonin reuptake inhibitors (SSRIs) highlighting the importance of patent‐related confounding by indication

open access: yesActa Psychiatrica Scandinavica, Volume 150, Issue 4, Page 198-208, October 2024.
Abstract Background The comparative effectiveness of selective serotonin reuptake inhibitors (SSRIs) has been subjected to relatively little research. However, a recent study based on target trial emulation suggested that sertraline may be more effective than escitalopram.
Christopher Rohde   +2 more
wiley   +1 more source

Combination Headache: Practical Experience with a Combination of a β-Blocker and an Antidepressive

open access: yes, 1986
In the prophylaxis of migraine β-blockers are commonly used. In the therapy of tension headache (TH) the use of tricyclic antidepressives is widespread.
U Kellhammer, W Pöllmann, V Pfaffenrath
core   +1 more source

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