Results 31 to 40 of about 1,565,191 (184)
Contribution of physiological dynamics in predicting major depressive disorder severity
Abstract This study aimed to explore the physiological dynamics of cognitive stress in patients with Major Depressive Disorder (MDD) and design a multiparametric model for objectively measuring severity of depression. Physiological signal recordings from 40 MDD patients and 40 healthy controls were collected in a baseline stage, in a stress‐inducing ...
Esther García Pagès +11 more
wiley +1 more source
Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian [PDF]
Two new tricyclic alkaloids, polycitorols A (1) and B (2) have been isolated along with the known lepadiformine (3) from a marine ascidian of the family Polycitoridae.
Setiawan, Andi +5 more
core
Antiepileptic and antidepressive polypharmacy in patients with multiple sclerosis. [PDF]
Objective. Patients with multiple sclerosis (MS) are often suffering from neuropathic pain. Antiepileptic drugs (AEDs) and tricyclic antidepressants (TCAs) are commonly used and are susceptible to be involved in drug interactions.
Beiske, Antonie Giæver +4 more
core +1 more source
Drug‐induced rhabdomyolysis has become increasingly prevalent due to the rising use of medications such as statins, antidepressants, and antipsychotics. These can lead to muscle cell destruction and the release of myoglobin, potentially causing kidney damage.
Sebastian Hafner +5 more
wiley +1 more source
Synthesis and Transformation of Tricyclic KYNA Derivatives [PDF]
Kynurenic acid (KYNA) derivatives condensed with an aromatic ring (tricyclic KYNA derivatives) have been successfully synthesized, and the reactivity of these analogues has been investigated in the modified Mannich reaction resulting in new Mannich bases.
Bálint Lőrinczi +5 more
core +1 more source
Aims In many countries, pain is the most common indication for use of antidepressants in older adults. We reviewed the evidence from randomized controlled trials on the efficacy and safety of antidepressants, compared to all alternatives for pain in older adults (aged ≥65 years).
Sujita W. Narayan +10 more
wiley +1 more source
Rg1 exhibits antidepressant effects through diverse mechanisms, such as anti‐inflammation, synaptic protection, neurogenesis promotion, brain‐derived neurotrophic factor release, enhancement of astrocyte gap junction function, and regulation of hypothalamic–pituitary–adrenal axis and antioxidative stress. Experimental studies validate Rg1's efficacy in
Dong Han +5 more
wiley +1 more source
Oxazolidinone Antibacterial Agents. An Enantioselective Synthesis of the [6,5,5] Tricyclic Fused Oxazolidinone Ring System and Application to the Synthesis of a Rigid DuP 721 ...
D. Mark Gleave (3038250) +1 more
core +1 more source
Abstract Background The comparative effectiveness of selective serotonin reuptake inhibitors (SSRIs) has been subjected to relatively little research. However, a recent study based on target trial emulation suggested that sertraline may be more effective than escitalopram.
Christopher Rohde +2 more
wiley +1 more source
Combination Headache: Practical Experience with a Combination of a β-Blocker and an Antidepressive
In the prophylaxis of migraine β-blockers are commonly used. In the therapy of tension headache (TH) the use of tricyclic antidepressives is widespread.
U Kellhammer, W Pöllmann, V Pfaffenrath
core +1 more source

