Results 31 to 40 of about 1,519,564 (181)

Lithium Augmentation in Treatment‐Resistant Depression: A Qualitative Review of the Literature

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 688-701, October 2025.
ABSTRACT Depression is the leading cause of disability worldwide, affecting people of all ages. Both pharmacological and non‐pharmacological therapies are available for its treatment. However, some patients do not respond to first‐line pharmacological interventions, referred to as treatment‐resistant depression (TRD).
Angela Acero‐González   +8 more
wiley   +1 more source

Correlation of antidepressive agents and the mortality of end-stage renal disease

open access: yes, 2012
[[abstract]]Aim:Depression is one of the most common psychological disorders in end-stage renal disease (ESRD) patients and is associated with impaired quality of life and increased mortality and rate of hospitalization.
Tsai, CJ;Loh, EW;Lin, CH;Yu, TM;Chan, CH;Lan, TH
core   +1 more source

The Effect of ABCB1 Polymorphisms on the Efficacy of Antidepressants

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 137, Issue 4, October 2025.
ABSTRACT This scoping review investigates the association between ABCB1 polymorphisms and antidepressant efficacy in humans. A systematic search identified 630 records, of which 58 met the inclusion criteria, resulting in 42 unique studies (five randomised controlled trials (RCTs), two randomised studies (non‐RCTs), 30 prospective cohort studies, three
Sofie Voss Thorsen   +3 more
wiley   +1 more source

Depression, antidepressant use, and breast cancer incidence: results from the E3N prospective cohort

open access: yesPsychiatry and Clinical Neurosciences, Volume 79, Issue 9, Page 554-560, September 2025.
Aim Depression and antidepressant drugs may both impact breast cancer incidence, potentially in opposite directions. The few epidemiological studies attempting to disentangle their effects have been inconclusive. We aimed to assess within the same prospective cohort the association between depression, antidepressant use, and breast cancer risk, while ...
Romain Colle   +7 more
wiley   +1 more source

Mirtazapine versus other antidepressive agents for depression.

open access: yes, 2011
BACKGROUND: Mirtazapine has a unique mechanism of antidepressive action and is one of the commonly used antidepressants in clinical practice. OBJECTIVES: The aim of the present review was to assess the evidence on the efficacy and acceptability of ...
Churchill, R   +25 more
core   +1 more source

The Global Landscape of Neuropsychiatric Prescribing Practices of Nurses: A Scoping Review

open access: yesInternational Journal of Mental Health Nursing, Volume 34, Issue 4, July 2025.
ABSTRACT Mental healthcare service access in South Africa is currently strained due to, among others, shortages of specialised mental healthcare professionals. The National Strategic Plan for HIV, TB and STIs (2023‐2028) recommends enabling nurses to diagnose, prescribe and dispense neuropsychiatric medication for promoting mental health services.
M. Naidoo, C. J. Filmalter, W. Cordier
wiley   +1 more source

The Study of Clinical Finding, Complications and Management of 24 Patients with Overused T.C.A.

open access: yesپزشکی بالینی ابن سینا, 1999
The extensive use of tricyclic antidepression drugs, the approximation of the therapeutic levels of the drugs to toxic level and the availability of the drugs to depressed patients who have potentially the idea of committing suicide has made these drugs ...
Saeed Fallah   +2 more
doaj  

Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy

open access: yesMedComm, Volume 6, Issue 5, May 2025.
Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes   +4 more
wiley   +1 more source

Pharmacological Treatment of Neuropsychiatric Symptoms in Huntington's Disease: A Systematic Review

open access: yesMovement Disorders Clinical Practice, Volume 12, Issue 4, Page 418-431, April 2025.
ABSTRACT Background Studies focusing on the treatment of neuropsychiatric symptoms (NPS) in Huntington's disease (HD) are scarce and show a wide variation in design, outcome measures and methodological quality. The effectiveness of pharmacological treatment of NPS in HD has not been systematically reviewed so far.
Ruben L. Andriessen   +5 more
wiley   +1 more source

Sertraline versus other antidepressive agents for depression.

open access: yes, 2009
BACKGROUND: The National Institute for Health and Clinical Excellence clinical practice guideline on the treatment of depressive disorder recommended that selective serotonin reuptake inhibitors should be the first-line option when drug therapy is ...
Churchill, Rachel C   +24 more
core   +1 more source

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