Results 11 to 20 of about 1,519,564 (181)

The Brugada Type 1 Electrocardiogram and Ventricular Tachycardia With High-Dose Amitriptyline

open access: yesJACC: Case Reports, 2021
A 32-year-old woman with anorexia nervosa experienced ventricular tachycardia while on therapeutic-dose amitriptyline despite normal blood tests, imaging, and intracardiac recordings.
Ji-Jian Chow, MRCP   +2 more
doaj   +1 more source

Antidepressant Use and the Risk of Major Adverse Cardiovascular Events in Patients Without Known Cardiovascular Disease: A Retrospective Cohort Study

open access: yesFrontiers in Pharmacology, 2020
Aims: Conflicting data exist on whether an association exists between antidepressants and the risk of major adverse cardiovascular events (MACEs) in patients with depression.
Ha Young Jang   +8 more
doaj   +1 more source

Polycitorols A and B, New Tricyclic Alkaloids from an Ascidian [PDF]

open access: yes, 2005
Two new tricyclic alkaloids, polycitorols A (1) and B (2) have been isolated along with the known lepadiformine (3) from a marine ascidian of the family Polycitoridae.
Setiawan, Andi   +5 more
core   +2 more sources

Evaluating the effects of physical activity and antidepressive agents on depressive symptoms in older adults: a meta-analysis of existing evidence. [PDF]

open access: yesBMC Geriatr
Background Although a wide range of treatments for depression are currently available, the condition continues to pose a substantial threat to the physical health of older adults.
Zhang S, Miao C.
europepmc   +2 more sources

Ferulic acid as a therapeutic agent in depression: Evidence from preclinical studies

open access: yesCNS Neuroscience &Therapeutics, Volume 29, Issue 9, Page 2397-2412, September 2023., 2023
Abstract Depression is a common but severe mood disorder with a very high prevalence across the general population. Depression is of global concern and poses a threat to human physical and mental health. Ferulic acid (FA) is a natural active ingredient that has antioxidative, anti‐inflammatory, and free radical scavenging properties.
Xiaoyu Dong, Dongxue Zhao
wiley   +1 more source

Lepidium meyenii Walp (Maca)‐derived extracellular vesicles ameliorate depression by promoting 5‐HT synthesis via the modulation of gut–brain axis

open access: yesiMeta, Volume 2, Issue 3, August 2023., 2023
We successfully isolated Maca‐EVs using ultracentrifugation and tested its antidepressant effects in the unpredictable chronic mild stress mice. Maca‐EVs increased serum serotonin (5‐HT) levels probably via the gut microbiota and metabolism modulation.
Rui Hong   +14 more
wiley   +1 more source

Increased risk of depression after Guillain‐Barré syndrome

open access: yesMuscle &Nerve, Volume 67, Issue 6, Page 497-505, June 2023., 2023
Abstract Introduction/Aims Guillain‐Barré syndrome (GBS) is a potentially life‐threatening disorder, and some patients may develop subsequent depression related to traumatic stress or permanent loss of motor function. We determined the short‐term (0 to 2 years) and long‐term (>2 years) risk of depression after GBS.
Lotte Sahin Levison   +2 more
wiley   +1 more source

Novel drug developmental strategies for treatment‐resistant depression

open access: yesBritish Journal of Pharmacology, Volume 179, Issue 6, Page 1146-1186, March 2022., 2022
Major depressive disorder is a leading cause of disability worldwide. Because conventional therapies are ineffective in many patients, novel strategies are needed to overcome treatment‐resistant depression (TRD). Limiting factors of successful drug development in the last decades were the lack of (1) knowledge of pathophysiology, (2) translational ...
Éva Borbély   +5 more
wiley   +1 more source

Antidepressant use and stroke or mortality risk in the elderly

open access: yesEuropean Journal of Neurology, Volume 29, Issue 2, Page 469-477, February 2022., 2022
In real‐world data of the elderly population, it was found that the risk of experiencing stroke or death in antidepressant users during and up to 1 year after exposure was higher compared to non‐users, even after adjustment for possible confounders. Abstract Background and purpose Current evidence on antidepressant‐related stroke or mortality risk is ...
Begüm Irmak Ön   +7 more
wiley   +1 more source

Expedient Single Step Access to Strained Tricyclic Ketals [PDF]

open access: yes, 2021
The synthesis of cyclopropyl methyl ketones and highly strained fused substituted dihydrobenzopyran cyclopropyl lactones derived from coumarin carboxylates and chloroacetone in the presence of potassium carbonate is reported. One step synthetic access to
Jered, Garrison   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy