Results 1 to 10 of about 20,972 (210)
Imipramine inhibits feline infectious peritonitis virus infection by targeting host cholesterol metabolism via NPC1 [PDF]
Antimicrobial Agents and ChemotherapyFeline infectious peritonitis (FIP), a fatal disease caused by FIP virus (FIPV), currently lacks effective vaccines and treatments. Imipramine, a tricyclic antidepressant with known broad-spectrum antiviral properties, was investigated for its efficacy ...
Rui Jing +7 more
doaj +2 more sources
Time of Administration of Acute or Chronic Doses of Imipramine Affects its Antidepressant Action in Rats [PDF]
Journal of Circadian Rhythms, 2018 The pathogenesis and therapeutics of depression are linked to the operation of the circadian system. Here, we studied the chronopharmacological action of a tricyclic antidepressant, imipramine. Male adult Wistar–Hannover rats were administered imipramine
Hiroshi Kawai +6 more
doaj +4 more sources
The effect of imipramine on the behavior of albino mice in presence of selenium
Libyan International Medical University Journal, 2016 Introduction: Imipramine, a tricyclic antidepressant used in the treatment of depression, anxiety, and other mental condition. Selenium is useful in managing depression and anxiety.
S Aburawi, S Baayo
doaj +2 more sources
Neural Regeneration Research, 2016 Retinal ganglion cell (RGC) degeneration is irreversible in glaucoma and tyrosine kinase receptor B (TrkB)-associated signaling pathways have been implicated in the process.
Ming-lei Han +4 more
doaj +2 more sources
Journal of Aziz Fatimah Medical and Dental College, 2022 Objective: To assess the anti-depressant and anxiolytic effect of tramadol as compared to imipramine (approved antidepressant) in acute and chronic doses in rats.
Fiza Soomro +3 more
doaj +1 more source
PLoS ONE, 2021 We previously reported that treatment with the prototypical antidepressant imipramine induced a dose-dependent reduction of the ingestion of a 10% sucrose solution, due to reduction of the licking burst number, thus suggesting reduced motivation and/or ...
Paolo S D'Aquila, Adriana Galistu
doaj +1 more source
Frontiers in Oncology, 2021 BackgroundAnti-depressants have been reported to own anti-tumor potential types of cancers; however, the role of imipramine in non-small cell lung cancer (NSCLC) has not been elucidated.
Po-Fu Yueh +9 more
doaj +1 more source
Frontiers in Oncology, 2023 BackgroundTumor invasion and metastasis are responsible for the majority of cancer-related deaths. The identification of molecules involved in these processes is crucial to design effective treatments that can halt the progression of cancer.
Antonio Asensi-Cantó +8 more
doaj +1 more source
Modulation of 8-OH-DPAT-Induced Hypothermia by Imipramine in Rats
Journal of Pharmacological Sciences, 2003 : The effects of imipramine on 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT), the 5-hydroxytryptamine (5-HT)1A-receptor full agonist, -induced hypothermia was examined in rats.
Yoshihisa Kitamura +4 more
doaj +1 more source
Veterinary Sciences, 2021 Imipramine is a tricyclic antidepressant that has been approved for treating depression and anxiety in patients and animals and that has relatively mild side effects.
Geng-Ruei Chang +8 more
doaj +1 more source